Key Insights

Highlights

Success Rate

89% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

5.9%

2 terminated out of 34 trials

Success Rate

88.9%

+2.3% vs benchmark

Late-Stage Pipeline

3%

1 trials in Phase 3/4

Results Transparency

25%

4 of 16 completed with results

Key Signals

4 with results89% success

Data Visualizations

Phase Distribution

20Total
Not Applicable (13)
P 1 (2)
P 2 (4)
P 3 (1)

Trial Status

Completed16
Recruiting11
Withdrawn2
Unknown2
Terminated2
Active Not Recruiting1

Trial Success Rate

88.9%

Benchmark: 86.5%

Based on 16 completed trials

Clinical Trials (34)

Showing 20 of 20 trials
NCT07220226Not ApplicableRecruitingPrimary

Venous Compression in Fontan

NCT03322345Terminated

Characterizing the Effect of Dopamine on Markers of Lymph Re-circulation in Fontan-associated Protein-losing Enteropathy

NCT04901975Phase 1CompletedPrimary

Fibrosis and the Fontan

NCT04195451Not ApplicableCompletedPrimary

Re-Energize Fontan

NCT07087782Not ApplicableRecruitingPrimary

Impact of Early Fortini Initiation on Growth and Interstage Outcomes in Infants With Single Ventricle Physiology

NCT03404258Active Not RecruitingPrimary

ET1 Concentration, Metabolic Pathway Activation, and Pulmonary Blood Flow in Infants Undergoing Superior Cavo-Pulmonary Anastomosis

NCT06918795Not ApplicableRecruitingPrimary

Fontan Fitness Trial

NCT06434207Recruiting

Extracellular Vesicle Micro RNA Profiling in Congenital Heart Disease: Fetal-Maternal Regulation in Neonatal Thrombosis

NCT06613477Phase 1RecruitingPrimary

PK/PD of Digoxin in Infants With SVHD

NCT06150950Not ApplicableRecruiting

REHAB Fontan Failure: A Trial of Cardiac Rehabilitation

NCT05262907Not ApplicableRecruiting

Ventripoint Single Ventricle Study

NCT07073612RecruitingPrimary

Transcatheter Fontan Stenting: Impact on Hepatic Stiffness and Exercise Capacity

NCT04467671Phase 2Recruiting

Two-Year Study of the Safety and Efficacy of the Second-Generation Tissue Engineered Vascular Grafts

NCT04106479Recruiting

NIRS in Congenital Heart Defects - Correlation With Echocardiography

NCT05634226Not ApplicableCompletedPrimary

Simple Non-invasive Breathing Device to Improve Pulmonary Flow Pusatility in Single Ventricle Post Fontan

NCT05034354Not ApplicableCompleted

Virtual Remote Physiological Monitoring Program of Children With Heart Disease

NCT02975999Phase 2Completed

Use of Vasopressin Following the Fontan Operation

NCT06538571Not ApplicableRecruitingPrimary

Association of Near Infrared Spectroscopy With Interstage Outcomes

NCT05011565CompletedPrimary

Hemodynamic, Vascular and Muscular Parameters of Exercise Capacity in Single-Ventricle Patients With Fontan Procedure

NCT03339466Not ApplicableCompletedPrimary

Inspiratory Muscle Therapy in Subjects With Fontan Circulations

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