Key Insights

Highlights

Success Rate

100% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Low Risk

Score: 27/100

Termination Rate

0.0%

0 terminated out of 24 trials

Success Rate

100.0%

+13.5% vs benchmark

Late-Stage Pipeline

13%

3 trials in Phase 3/4

Results Transparency

41%

7 of 17 completed with results

Key Signals

7 with results100% success

Data Visualizations

Phase Distribution

23Total
P 1 (15)
P 2 (5)
P 3 (2)
P 4 (1)

Trial Status

Completed17
Active Not Recruiting3
Recruiting2
Withdrawn1
Unknown1

Trial Success Rate

100.0%

Benchmark: 86.5%

Based on 17 completed trials

Clinical Trials (24)

Showing 20 of 20 trials
NCT06615375Phase 2Active Not RecruitingPrimary

A Human Challenge Study to Assess Protection of a Shigella Tetravalent Bioconjugate Vaccine

NCT06523231Phase 2CompletedPrimary

Study to Expand Safety and Immunogenicity Data With Shigella Bioconjugate Vaccine (Shigella4V2) in 9-month-old Infants.

NCT05121974Phase 2Active Not RecruitingPrimary

Tebipenem Trial in Children With Shigellosis

NCT05182749Phase 1Active Not RecruitingPrimary

Safety and Efficacy of the Bacteriophage Preparation, ShigActive™, in a Human Experimental Model of Shigellosis

NCT05959616Phase 1RecruitingPrimary

Shigella Sonnei 53G Human Infection Study in Kenyan Adults

NCT04992520Phase 1CompletedPrimary

Controlled Human Infection Model Challenge/Rechallenge

NCT05961059Phase 1RecruitingPrimary

InvaplexAR-Detox and DmLT Adjuvant in the Netherlands and Zambia

NCT04056117Phase 1CompletedPrimary

A Study to Determine If a New Shigella Vaccine is Safe, Induces Immunity and The Best Dose Among Kenyan Infants

NCT03854929Phase 4Completed

Ciprofloxacin Versus Azithromycin for Children Hospitalised With Dysentery

NCT05156528Phase 3Unknown

Efficacy, Immunogenicity and Safety of S. Flexneriza-S. Sonnei Bivalent Conjugate Vaccine in Volunteers Aged From 6 Months to 5 Years

NCT01509846Phase 1CompletedPrimary

Safety Study of Inactivated Shigella Whole Cell Vaccine in Adults

NCT02445963Phase 1CompletedPrimary

Safety and Immunogenicity of Artificial Invaplex (Shigella Flexneri 2a InvaplexAR)

NCT02646371Phase 2CompletedPrimary

Phase 2b Challenge Study With the Bioconjugate Vaccine Flexyn2a

NCT01369927Phase 1Completed

Shigella Sonnel O-SPC/rBRU Conjugate Vaccine

NCT02017899Phase 1CompletedPrimary

A Phase 1, Dose Escalation Study, to Evaluate a New Shigella Sonnei Vaccine in Healthy Adults.

NCT02797236Phase 1CompletedPrimary

SF2a-TT15 Conjugate Vaccine in Healthy Adult Volunteers

NCT00485134Phase 1CompletedPrimary

Shigella Flexneri 2a Invaplex 50 Vaccine Dose Finding and Assessment of Protection

NCT01399424Phase 1WithdrawnPrimary

Shigella Sonnei OSPC-rDT Conjugate Vaccine

NCT02105714Completed

Diagnosis of Neglected Tropical Diseases Among Patients With Persistent Digestive Disorders

NCT02034500Phase 1CompletedPrimary

Evaluate a New Shigella Sonnei Vaccine Administered Either by Intradermal, Intranasal or Intramuscular Route in Healthy Adults

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