Key Insights

Highlights

Success Rate

85% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

11.8%

6 terminated out of 51 trials

Success Rate

85.0%

-1.5% vs benchmark

Late-Stage Pipeline

20%

10 trials in Phase 3/4

Results Transparency

26%

9 of 34 completed with results

Key Signals

9 with results85% success

Data Visualizations

Phase Distribution

40Total
Not Applicable (5)
Early P 1 (2)
P 1 (10)
P 2 (13)
P 3 (8)
P 4 (2)

Trial Status

Completed34
Terminated6
Recruiting5
Active Not Recruiting2
Withdrawn2
Not Yet Recruiting1

Trial Success Rate

85.0%

Benchmark: 86.5%

Based on 34 completed trials

Clinical Trials (51)

Showing 20 of 20 trials
NCT07299019Phase 3RecruitingPrimary

A Study of Orelabrutinib in Patients With Secondary Progressive Multiple Sclerosis

NCT06372145Phase 3Active Not Recruiting

A Study to Investigate Long-term Safety and Tolerability of Tolebrutinib in Participants With Multiple Sclerosis.

NCT05327322Not ApplicableRecruiting

Functional Outcomes From Diets in Multiple Sclerosis

NCT04047628Phase 3Recruiting

Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)

NCT06292923Phase 2RecruitingPrimary

A Study of Nasal Foralumab in Non-Active Secondary Progressive Multiple Sclerosis Patients

NCT07168694CompletedPrimary

A Real-world Study About the Impact of Siponimod Treatment on Secondary Progressive Multiple Sclerosis Patients in Russia

NCT03783416Phase 1Recruiting

SIZOMUS Safety of Ixazomib Targeting Plasma Cells in Multiple Sclerosis

NCT04688788Phase 3Active Not Recruiting

Non-inferiority Study of Ocrelizumab and Rituximab in Active Multiple Sclerosis

NCT03471338Not ApplicableCompleted

Neuropsychological Management of Multiple Sclerosis: Benefits of a Computerised Semi-autonomous At-home Cognitive Rehabilitation Programme

NCT05349474Early Phase 1CompletedPrimary

Metformin Treatment in Progressive Multiple Sclerosis

NCT03896217Phase 2CompletedPrimary

Simvastatin in Secondary Progressive Multiple Sclerosis

NCT06887426Not Yet Recruiting

Cladribine Tablets as an Exit Therapy Strategy

NCT01950234Phase 2TerminatedPrimary

ACTH in Progressive Forms of MS

NCT06588387CompletedPrimary

A Real-world Study to Assess the Use of Siponimod in Spain to Treat Patients With Secondary Progressive Multiple Sclerosis

NCT06526000Completed

Study to Assess Changes in Immunoglobulins in Patients With Relapsing Multiple Sclerosis Treated With Anti-CD20 Therapies

NCT04792567Phase 4CompletedPrimary

Exploring the Immune Response to SARS-CoV-2 modRNA Vaccines in Patients With Secondary Progressive Multiple Sclerosis (AMA-VACC)

NCT01665144Phase 3CompletedPrimary

Exploring the Efficacy and Safety of Siponimod in Patients With Secondary Progressive Multiple Sclerosis (EXPAND)

NCT06395909Completed

A Study to Assess the Effectiveness and Safety of Mayzent in Chinese Patients With Relapsing Forms of Multiple Sclerosis

NCT03283826Phase 1Terminated

Phase 1/2 Study to Evaluate the Safety and Efficacy of ATA188 in Subjects With Progressive Multiple Sclerosis

NCT05357833Early Phase 1CompletedPrimary

Novel Imaging Markers in SPMS

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Research Network

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