Key Insights

Highlights

Success Rate

95% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 40/100

Termination Rate

2.2%

1 terminated out of 46 trials

Success Rate

94.7%

+8.2% vs benchmark

Late-Stage Pipeline

13%

6 trials in Phase 3/4

Results Transparency

0%

0 of 18 completed with results

Key Signals

95% success

Data Visualizations

Phase Distribution

30Total
Not Applicable (18)
P 1 (2)
P 2 (4)
P 3 (6)

Trial Status

Completed18
Unknown8
Recruiting7
Not Yet Recruiting7
Active Not Recruiting4
Terminated1

Trial Success Rate

94.7%

Benchmark: 86.6%

Based on 18 completed trials

Clinical Trials (46)

Showing 20 of 20 trials
NCT07753681Recruiting

Domestication and Implementation of the PEN-Plus Clinical Model in the Zambian Health System

NCT07606131Not ApplicableNot Yet RecruitingPrimary

Testing a Registry-Based Strategy (ACT+) to Reduce Loss to Follow-Up in Rheumatic Heart Disease Screening in Uganda

NCT05693545Phase 2Active Not RecruitingPrimary

GOALIE: Intramuscular vs. Enteral Penicillin Prophylaxis to Prevent Progression of Latent RHD Trial

NCT07146048Phase 3RecruitingPrimary

A Non-Inferiority Trial of Stopping Penicillin in Early Rheumatic Heart Disease: GOAL-Stop

NCT07599956Not ApplicableNot Yet RecruitingPrimary

Artificial Intelligence to Scale Early Rheumatic Heart Disease Detection

NCT05783375Not ApplicableRecruitingPrimary

Accelerating Delivery of rheUmatic Heart Disease Preventive iNterventions in Northern Uganda

NCT04936815Not ApplicableActive Not Recruiting

Echocardiographic Screening of Pregnant Women During Antenatal Care

NCT07146282Not Yet RecruitingPrimary

Vitamin K Antagonist in Rheumatic Heart Disease Patients With Mechanical Heart Valves: Our Current Status

NCT07078357Phase 1Not Yet RecruitingPrimary

Clinical Trial Phase I/IIa to Evaluate the Safety and Immunogenicity of StreptInCor

NCT07068633Not Yet Recruiting

Korea VHD Echo Study: Surveillance of Aortic, Mitral & Tricuspid Patients - Insights From Real-world Practice

NCT07065474Not ApplicableNot Yet RecruitingPrimary

Effectiveness of Edutainment-Based Interventions in Increasing Knowledge of Rheumatic Fever and Rheumatic Heart Disease Among School-Going Children in Nepal: Study Protocol for Colors to Save Hearts Quasi-Experimental Pretest-Posttest Study

NCT04556188RecruitingPrimary

The Clinical Influence of Developing a Sustainable Cardiac Surgery Service to Reduce the Burden of Rheumatic Heart Disease in Sub-Saharan Africa

NCT06952374Not ApplicableRecruiting

Treating Severe Mitral Valve Annular or Valvular Calcification Using Shockwave Balloon SMARTWAVE

NCT05211024CompletedPrimary

A Long-term Follow up Study for Patients Who Participated in the GOAL Trial (GOAL-Post)

NCT02118818CompletedPrimary

RhEumatiC Heart diseAse Genetics

NCT06150274Not ApplicableCompletedPrimary

Comparison of Wire Assisted Percutaneous Balloon Mitral Valvulotomy With Standard Inoue Balloon Valvulotomy

NCT05276999Not ApplicableCompletedPrimary

Rheumatic Heart Disease Community Streptococcal Treatment Program "RESET"

NCT06002243Not ApplicableNot Yet RecruitingPrimary

Non-Expert Acquisition & Remote Expert Review of Screening Echocardiography Images From Child Health & AnteNatal Clinics

NCT05668611Not ApplicableCompletedPrimary

Train the Trainer Curriculum to Scale up AI Supported Echo for RHD Screening in a Public Health System

NCT05502042Not ApplicableCompletedPrimary

Case Management and Peer Support Groups for Prophylaxis Adherence in Rheumatic Heart Disease

Scroll to load more

Research Network

Activity Timeline