Key Insights

Highlights

Success Rate

86% trial completion

Published Results

32 trials with published results (15%)

Research Maturity

102 completed trials (48% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

7.6%

16 terminated out of 211 trials

Success Rate

86.4%

-0.1% vs benchmark

Late-Stage Pipeline

6%

12 trials in Phase 3/4

Results Transparency

31%

32 of 102 completed with results

Key Signals

32 with results86% success16 terminated

Data Visualizations

Phase Distribution

144Total
Not Applicable (53)
Early P 1 (4)
P 1 (49)
P 2 (26)
P 3 (11)
P 4 (1)

Trial Status

Completed102
Recruiting29
Unknown26
Active Not Recruiting23
Terminated16
Not Yet Recruiting6

Trial Success Rate

86.4%

Benchmark: 86.6%

Based on 102 completed trials

Clinical Trials (211)

Showing 20 of 20 trials
NCT03999021Phase 1Active Not RecruitingPrimary

FIGHT-RP 1 Extension Study

NCT01432847Recruiting

Cell Collection to Study Eye Diseases

NCT02617966Recruiting

Rod and Cone Mediated Function in Retinal Disease

NCT04127006CompletedPrimary

Rate of Progression in EYS Related Retinal Degeneration

NCT05203939Phase 1Active Not RecruitingPrimary

Study to Assess the Safety and Efficacy of OCU400 for Retinitis Pigmentosa and Leber Congenital Amaurosis

NCT06574997UnknownPrimary

Expanded Access Program for RP in Adults

NCT06388200Phase 3Active Not RecruitingPrimary

A Phase 3 Study Of OCU400 Gene Therapy for the Treatment Of Retinitis Pigmentosa

NCT06912633Phase 2Active Not RecruitingPrimary

Safety of a Single, Intravitreal Injection of 6.0M jCell (Famzeretcel) in Retinitis Pigmentosa (RP)

NCT07509229Phase 1Enrolling By InvitationPrimary

9-cis Beta-Carotene-Rich Extract of Dunaliella Alga in Retinitis Pigmentosa Patients

NCT05926583Phase 3Active Not RecruitingPrimary

A Study of AAV5-hRKp.RPGR for the Treatment of Japanese Participants With X-linked Retinitis Pigmentosa

NCT03944239Phase 1Active Not RecruitingPrimary

Safety and Efficacy of Subretinal Transplantation of Clinical Human Embryonic Stem Cell Derived Retinal Pigment Epitheliums in Treatment of Retinitis Pigmentosa

NCT03011541Not ApplicableRecruiting

Stem Cell Ophthalmology Treatment Study II

NCT05589714Recruiting

Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants

NCT06628947Phase 2RecruitingPrimary

A Phase II Study of Intravitreal KIO-301 in Patients With Late-stage Retinitis Pigmentosa

NCT06952842Phase 1RecruitingPrimary

Safety and Efficacy of ZVS203e in the Treatment of Retinitis Pigmentosa Caused by RHO Gene Mutation

NCT05537220Phase 3Active Not RecruitingPrimary

Oral N-acetylcysteine for Retinitis Pigmentosa

NCT03374657Phase 1CompletedPrimary

A First-in-human, Proof of Concept Study of CPK850 in Patients With RLBP1 Retinitis Pigmentosa

NCT00254605RecruitingPrimary

Retinal Imaging in Patients With Inherited Retinal Degenerations

NCT07408232Phase 1Active Not RecruitingPrimary

A Phase 1/2 Study in Healthy Volunteers and Participants With Autosomal Dominant Retinitis Pigmentosa (RHO-adRP)

NCT02435940Recruiting

Inherited Retinal Degenerative Disease Registry

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