Key Insights

Highlights

Success Rate

81% trial completion

Published Results

20 trials with published results (47%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 47/100

Termination Rate

11.6%

5 terminated out of 43 trials

Success Rate

81.5%

-5.0% vs benchmark

Late-Stage Pipeline

5%

2 trials in Phase 3/4

Results Transparency

91%

20 of 22 completed with results

Key Signals

20 with results81% success

Data Visualizations

Phase Distribution

42Total
Early P 1 (2)
P 1 (20)
P 2 (18)
P 3 (2)

Trial Status

Completed22
Active Not Recruiting6
Recruiting5
Terminated5
Unknown3
Not Yet Recruiting1

Trial Success Rate

81.5%

Benchmark: 86.5%

Based on 22 completed trials

Clinical Trials (43)

Showing 20 of 20 trials
NCT05272384Phase 1Recruiting

Testing the Combination of Nivolumab and ASTX727 for Relapsed or Refractory B-Cell Lymphoma

NCT03057795Phase 2Active Not Recruiting

Nivolumab & Brentuximab Vedotin Consolidation After Autologous SCT in Patients With High-Risk Classical Hodgkin Lymphoma

NCT01231412Phase 3Completed

Graft-Versus-Host Disease Prophylaxis in Treating Patients With Hematologic Malignancies Undergoing Unrelated Donor Peripheral Blood Stem Cell Transplant

NCT04134325Early Phase 1Active Not Recruiting

Study of PD-1 Inhibitors After CD30.CAR T Cell Therapy in Relapsed/Refractory Hodgkin Lymphoma

NCT03213665Phase 2Completed

Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial)

NCT06487624Phase 1Recruiting

An Engineered Sirpα Fused to Anti-Pd-L1 And Tgf-β Fusion Protein (HCB301) in Subjects With Selected Advanced Tumors

NCT07021989Phase 2Not Yet Recruiting

ctDNA-Guided Therapy for Relapsed/Refractory Hodgkin Lymphoma

NCT06484920Phase 2Recruiting

A Phase II Study of the Combination of Pembrolizumab and ATRA Combination Treatment of Relapsed HL and B-NHL

NCT04938232Phase 2Active Not Recruiting

Ipilimumab With or Without Nivolumab in Relapsed/Refractory cHL

NCT04681105Phase 1Completed

Flotetuzumab for the Treatment of Relapsed or Refractory Advanced CD123-Positive Hematological Malignancies

NCT04640779Phase 1Active Not Recruiting

Low-Dose Selinexor and Choline Salicylate for Non-Hodgkin or Hodgkin Lymphoma, Histiocytic/Dendritic Cell Neoplasm, or Relapsed or Refractory Multiple Myeloma

NCT04871607Phase 2Recruiting

Yttrium-90 Labeled Anti-CD25 Monoclonal Antibody Combined With BEAM Chemotherapy Conditioning for the Treatment of Primary Refractory or Relapsed Hodgkin Lymphoma

NCT02227199Phase 1Completed

Brentuximab Vedotin, Ifosfamide, Carboplatin, and Etoposide in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma

NCT03259503Phase 1Completed

Olaparib and High-Dose Chemotherapy in Treating Patients With Relapsed or Refractory Lymphomas Undergoing Stem Cell Transplant

NCT03016871Phase 2Active Not Recruiting

Nivolumab, Ifosfamide, Carboplatin, and Etoposide as Second-Line Therapy in Treating Patients With Refractory or Relapsed HL

NCT03739619Phase 1Completed

Gemcitabine, Bendamustine, and Nivolumab in Patients With Relapsed or Refractory Classical Hodgkin Lymphoma

NCT01703949Phase 2Active Not Recruiting

Brentuximab Vedotin With or Without Nivolumab in Treating Patients With Relapsed or Refractory CD30+ Lymphoma

NCT03432741Phase 1Terminated

Direct Tumor Microinjection and FDG-PET in Testing Drug Sensitivity in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma, Hodgkin Lymphoma, or Stage IV Breast Cancer

NCT02744612Phase 2Completed

Ibrutinib and Brentuximab Vedotin in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma

NCT05595447Phase 2Recruiting

Treatment Strategy for Relapsed/Refractory Hodgkin Lymphoma

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Research Network

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