Key Insights

Highlights

Success Rate

76% trial completion

Published Results

24 trials with published results (29%)

Research Maturity

54 completed trials (66% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 74/100

Termination Rate

20.7%

17 terminated out of 82 trials

Success Rate

76.1%

-10.5% vs benchmark

Late-Stage Pipeline

7%

6 trials in Phase 3/4

Results Transparency

44%

24 of 54 completed with results

Key Signals

24 with results76% success17 terminated

Data Visualizations

Phase Distribution

78Total
Not Applicable (10)
Early P 1 (1)
P 1 (33)
P 2 (28)
P 3 (6)

Trial Status

Completed54
Terminated17
Withdrawn4
Unknown3
Recruiting2
Not Yet Recruiting1

Trial Success Rate

76.1%

Benchmark: 86.5%

Based on 54 completed trials

Clinical Trials (82)

Showing 20 of 20 trials
NCT00826540Phase 2Completed

Sorafenib and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer

NCT04827732Not ApplicableTerminatedPrimary

Hypofractionated Pencil-Beam Scanning Intensity-modulated Proton Therapy (IMPT) in Recurrent Rectal Cancer

NCT01814501Phase 2Completed

Panitumumab and Chemotherapy in Patients With Advanced Colorectal Cancer After Prior Therapy With Bevacizumab

NCT06751394Phase 2Not Yet RecruitingPrimary

Preoperative Chemoradiotherapy and Toripalimab in Locally Recurrent Rectal Cancer

NCT05628038Phase 2RecruitingPrimary

The Combination of Hypofractionated Radiotherapy and Immunotherapy in Locally Recurrent Rectal Cancer

NCT02132858Completed

Genetic Mutations in Blood and Tissue Samples in Predicting Response to Treatment in Patients With Locally Advanced Rectal Cancer Undergoing Chemoradiation

NCT00407654Phase 2Completed

VEGF Trap in Treating Patients With Previously Treated Metastatic Colorectal Cancer

NCT00019006Phase 1Completed

Vaccine Therapy in Treating Patients With Colon, Pancreatic, or Lung Cancer

NCT01769222Phase 1Terminated

Ipilimumab and Local Radiation for Selected Solid Tumors

NCT02528175Not ApplicableCompletedPrimary

Magnetic Resonance-Guided High Intensity Focused Ultrasound for Recurrent Rectal Cancer

NCT00019760Phase 2Completed

Isolated Hepatic Perfusion With Melphalan Followed By Chemotherapy in Treating Patients With Unresectable Colorectal Cancer That is Metastatic to the Liver

NCT01740648Phase 1CompletedPrimary

Trametinib, Fluorouracil, and Radiation Therapy Before Surgery in Treating Patients With Stage II-III Rectal Cancer

NCT02232152Phase 1Completed

CPI-613 and Fluorouracil in Treating Patients With Metastatic Colorectal Cancer That Cannot Be Removed by Surgery

NCT04389086Phase 3RecruitingPrimary

Induction Chemotherapy for Locally Recurrent Rectal Cancer

NCT01285102Phase 1Terminated

Chemoembolization Using Irinotecan in Treating Patients With Liver Metastases From Metastatic Colon or Rectal Cancer

NCT04065984Not ApplicableActive Not Recruiting

Body Composition Manipulation in CoLorectal cancEr (BiCyCLE): Neuromuscular Electrical Stimulation (NMES)

NCT01987726Completed

Comprehensive Gene Sequencing in Guiding Treatment Recommendations Patients With Metastatic or Recurrent Solid Tumors

NCT05076305Unknown

PelvEx 4: Advanced Pelvic Malignancy and the Role of the Multi-disciplinary Team Meeting

NCT02270606Phase 1Completed

Phase I Study of Neoadjuvant Radiotherapy With 5-Fluorouracil for Rectal Cancer

NCT01807117Not ApplicableCompleted

PET-MRI in Diagnosing Patients With Colon or Rectal Cancer

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Research Network

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