Key Insights

Highlights

Success Rate

82% trial completion

Published Results

56 trials with published results (37%)

Research Maturity

69 completed trials (46% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 37/100

Termination Rate

10.0%

15 terminated out of 150 trials

Success Rate

82.1%

-4.4% vs benchmark

Late-Stage Pipeline

7%

11 trials in Phase 3/4

Results Transparency

81%

56 of 69 completed with results

Key Signals

56 with results82% success15 terminated

Data Visualizations

Phase Distribution

144Total
Not Applicable (8)
Early P 1 (5)
P 1 (54)
P 2 (66)
P 3 (10)
P 4 (1)

Trial Status

Completed69
Active Not Recruiting26
Recruiting17
Terminated15
Withdrawn13
Unknown7

Trial Success Rate

82.1%

Benchmark: 86.5%

Based on 69 completed trials

Clinical Trials (150)

Showing 20 of 20 trials
NCT02446600Phase 3Active Not Recruiting

Testing the Use of A Single Drug (Olaparib) or the Combination of Two Drugs (Cediranib and Olaparib) Compared to the Usual Chemotherapy for Women With Platinum Sensitive Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

NCT02627443Phase 1Active Not Recruiting

Carboplatin, Gemcitabine Hydrochloride, and Berzosertib in Treating Patients With Recurrent and Metastatic Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

NCT02595892Phase 2Active Not Recruiting

Gemcitabine Hydrochloride Alone or With M6620 in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

NCT05554328Phase 2Active Not Recruiting

Testing the Use of the Combination of Selumetinib and Olaparib or Selumetinib Alone Targeted Treatment for RAS Pathway Mutant Recurrent or Persistent Ovarian and Endometrial Cancers, A ComboMATCH Treatment Trial

NCT02839707Phase 2Active Not Recruiting

Pegylated Liposomal Doxorubicin Hydrochloride With Atezolizumab and/or Bevacizumab in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

NCT01012817Phase 1Active Not Recruiting

Veliparib and Topotecan Hydrochloride in Treating Patients With Solid Tumors, Relapsed or Refractory Ovarian Cancer, or Primary Peritoneal Cancer

NCT02101775Phase 2Active Not Recruiting

Gemcitabine Hydrochloride With or Without WEE1 Inhibitor MK-1775 in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

NCT02465060Phase 2Active Not Recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

NCT05564377Phase 2Recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

NCT02142803Phase 1Active Not Recruiting

TORC1/2 Inhibitor MLN0128 and Bevacizumab in Treating Patients With Recurrent Glioblastoma or Advanced Solid Tumors

NCT03586661Phase 1Completed

Niraparib and Copanlisib in Treating Patients With Recurrent Endometrial, Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

NCT06666218Not ApplicableSuspendedPrimary

Helping Ovarian Cancer Patients Cope With Their Illness (HOPE)

NCT04092270Phase 1Active Not Recruiting

A Study Combining the Peposertib (M3814) Pill With Standard Chemotherapy in Patients With Ovarian Cancer With an Expansion in High Grade Serous Ovarian Cancer and Low Grade Serous Ovarian Cancer

NCT04469764Phase 2Recruiting

Abemaciclib for the Treatment of Recurrent Ovarian or Endometrial Cancer

NCT03987555Suspended

Paclitaxel Therapeutic Drug Monitoring in Cancer Patients

NCT04550494Phase 2Active Not Recruiting

Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations

NCT03579316Phase 2Active Not Recruiting

Adavosertib With or Without Olaparib in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

NCT02068794Phase 1Active Not Recruiting

MV-NIS Infected Mesenchymal Stem Cells in Treating Recurrent Ovarian, Primary Peritoneal or Fallopian Tube Cancer

NCT01081262Phase 3Active Not Recruiting

Carboplatin and Paclitaxel or Oxaliplatin and Capecitabine With or Without Bevacizumab as First-Line Therapy in Treating Patients With Newly Diagnosed Stage II-IV or Recurrent Stage I Epithelial Ovarian or Fallopian Tube Cancer

NCT02502266Phase 2Active Not Recruiting

Testing the Combination of Cediranib and Olaparib in Comparison to Each Drug Alone or Other Chemotherapy in Recurrent Platinum-Resistant Ovarian Cancer

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Research Network

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