Key Insights

Highlights

Success Rate

64% trial completion

Published Results

27 trials with published results (61%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

29.5%

13 terminated out of 44 trials

Success Rate

63.9%

-22.6% vs benchmark

Late-Stage Pipeline

5%

2 trials in Phase 3/4

Results Transparency

117%

27 of 23 completed with results

Key Signals

27 with results64% success13 terminated

Data Visualizations

Phase Distribution

44Total
Not Applicable (3)
P 1 (18)
P 2 (21)
P 3 (2)

Trial Status

Completed23
Terminated13
Withdrawn4
Active Not Recruiting3
Unknown1

Trial Success Rate

63.9%

Benchmark: 86.5%

Based on 23 completed trials

Clinical Trials (44)

Showing 20 of 20 trials
NCT02206334Phase 1Completed

Stereotactic Body Radiation Therapy in Treating Patients With Metastatic Breast Cancer, Non-small Cell Lung Cancer, or Prostate Cancer

NCT02495896Phase 1Active Not Recruiting

Recombinant EphB4-HSA Fusion Protein With Standard Chemotherapy Regimens in Treating Patients With Advanced or Metastatic Solid Tumors

NCT02438722Phase 2Active Not RecruitingPrimary

S1403, Afatinib Dimaleate With or Without Cetuximab in Treating Patients With Newly Diagnosed Stage IV or Recurrent, EGFR Mutation Positive Non-small Cell Lung Cancer

NCT03137771Phase 2Active Not RecruitingPrimary

Maintenance Chemotherapy With or Without Local Consolidative Therapy in Treating Patients With Stage IV Non-small Cell Lung Cancer

NCT02823990Phase 2CompletedPrimary

TG4010 and Nivolumab in Patients With Lung Cancer

NCT03049618Phase 2Completed

Recombinant EphB4-HSA Fusion Protein and Pembrolizumab, MK-3475

NCT02186847Phase 2Completed

Chemotherapy and Radiation Therapy With or Without Metformin Hydrochloride in Treating Patients With Stage III Non-small Cell Lung Cancer

NCT01737502Phase 1Completed

Sirolimus and Auranofin in Treating Patients With Advanced or Recurrent Non-Small Cell Lung Cancer or Small Cell Lung Cancer

NCT02819024Not ApplicableCompletedPrimary

Dexamethasone Effects in Patients With Refractory Non-Small Cell Lung Cancer Using FLT Positron Emission Tomography

NCT02364609Phase 1CompletedPrimary

Pembrolizumab and Afatinib in Patients With Non-small Cell Lung Cancer With Resistance to Erlotinib

NCT02949843Phase 2Terminated

Targeted Therapy in Treating Patients With Incurable Non-Small Cell Lung Cancer With Genetic Mutations

NCT02073968Phase 2Completed

PET-Adjusted Intensity Modulated Radiation Therapy and Combination Chemotherapy in Treating Patients With Stage II-IV Non-small Cell Lung Cancer

NCT02581943Phase 2CompletedPrimary

Effect of Pembrolizumab With or Without Carboplatin and Paclitaxel on Immune Response in Patients With Recurrent or Stage IIIB-IV Non-small Cell Lung Cancer

NCT02947386Phase 1Completed

Nimotuzumab and Nivolumab in Treating Patients With Advanced Non-small Cell Lung Cancer

NCT00602797Phase 2CompletedPrimary

Vinorelbine Tartrate and Paclitaxel in Treating Older Patients With Advanced Non-Small Cell Lung Cancer

NCT03520842Phase 2Completed

Regorafenib and Methotrexate in Treating Participants With Recurrent or Metastatic KRAS Mutated Non-Small Cell Lung Cancer

NCT01971489Phase 1Withdrawn

Buparlisib, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Advanced Solid Tumors

NCT02400814Phase 1TerminatedPrimary

MPDL3280A and Stereotactic Ablative Radiotherapy in Patients With Non-small Cell Lung Cancer

NCT01854684Phase 1CompletedPrimary

Photodynamic Therapy During Surgery in Treating Patients With Non-small Cell Lung Cancer That Can Be Removed by Surgery

NCT00698815Phase 2CompletedPrimary

Pemetrexed and/or Sunitinib as Second-Line Therapy in Treating Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer

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