Key Insights

Highlights

Success Rate

78% trial completion

Published Results

77 trials with published results (39%)

Research Maturity

119 completed trials (60% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

17.2%

34 terminated out of 198 trials

Success Rate

77.8%

-8.8% vs benchmark

Late-Stage Pipeline

1%

1 trials in Phase 3/4

Results Transparency

65%

77 of 119 completed with results

Key Signals

77 with results78% success34 terminated

Data Visualizations

Phase Distribution

197Total
Not Applicable (13)
Early P 1 (4)
P 1 (110)
P 2 (69)
P 3 (1)

Trial Status

Completed119
Terminated34
Active Not Recruiting18
Withdrawn11
Recruiting8
Unknown6

Trial Success Rate

77.8%

Benchmark: 86.5%

Based on 119 completed trials

Clinical Trials (198)

Showing 20 of 20 trials
NCT07003295Phase 2RecruitingPrimary

Testing the Anti-cancer Drug, Glofitamab, in Patients With Mantle Cell Lymphoma (A Type of Blood Cancer) Whose Disease Returned After CAR-T Cell Therapy

NCT01479842Phase 1Active Not Recruiting

Rituxan/Bendamustine/PCI-32765 in Relapsed DLBCL, MCL, or Indolent Non-Hodgkin's Lymphoma

NCT01695941Phase 1Active Not Recruiting

Alisertib, Bortezomib, and Rituximab in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma or B-cell Low Grade Non-Hodgkin Lymphoma

NCT01880567Phase 2Active Not Recruiting

Ibrutinib and Rituximab in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma or Older Patients With Newly Diagnosed Mantle Cell Lymphoma

NCT07673367Phase 2Not Yet RecruitingPrimary

Nemtabrutinib With CAR T Therapy in Relapsed/Refractory Mantle Cell Lymphoma

NCT04205409Phase 2Completed

Nivolumab for Relapsed, Refractory, or Detectable Disease Post Chimeric Antigen Receptor T-cell Treatment in Patients With Hematologic Malignancies

NCT01815749Phase 1Active Not Recruiting

Genetically Modified T-cell Infusion Following Peripheral Blood Stem Cell Transplant in Treating Patients With Recurrent or High-Risk Non-Hodgkin Lymphoma

NCT03277729Phase 1Active Not Recruiting

A Phase I/II Study to Evaluate the Safety of Cellular Immunotherapy Using Autologous T Cells Engineered to Express a CD20-Specific Chimeric Antigen Receptor for Patients With Relapsed or Refractory B Cell Non-Hodgkin Lymphomas

NCT05453396Phase 2Terminated

Loncastuximab Tesirine for the Treatment of Relapsed or Refractory B-Cell Malignancies

NCT04054167Phase 2Active Not RecruitingPrimary

Ultra Low Dose Radiation Delivered Before or After Chemotherapy-Free Targeted Therapy in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma

NCT02159755Phase 1Active Not RecruitingPrimary

Ibrutinib and Palbociclib in Treating Patients With Previously Treated Mantle Cell Lymphoma

NCT01955499Phase 1Active Not Recruiting

Lenalidomide and Ibrutinib in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

NCT07578077Phase 1Not Yet RecruitingPrimary

Golcadomide in Combination With Rituximab for the Treatment of Patients With Relapsed or Refractory Mantle Cell Lymphoma

NCT01318317Phase 1Active Not Recruiting

Genetically Engineered Lymphocyte Therapy After Peripheral Blood Stem Cell Transplant in Treating Patients With High-Risk, Intermediate-Grade, B-cell Non-Hodgkin Lymphoma

NCT03035331Phase 1Completed

Dendritic Cell Therapy, Cryosurgery, and Pembrolizumab in Treating Patients With Non-Hodgkin Lymphoma

NCT03479268Phase 1Active Not Recruiting

Pevonedistat and Ibrutinib in Treating Participants With Relapsed or Refractory CLL or Non-Hodgkin Lymphoma

NCT06839053Phase 2Recruiting

Sonrotoclax, Rituximab, and Zanubrutinib in Treating Participants With Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, and Mantle Cell Lymphoma

NCT04939272Phase 1Active Not RecruitingPrimary

Copanlisib and Venetoclax for the Treatment of Relapsed or Refractory Mantle Cell Lymphoma

NCT06859008Phase 1Recruiting

Zanubrutinib in Combination With Sonrotoclax for the Treatment of Underrepresented Ethnic and Racial Minorities With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma

NCT02051257Phase 1Active Not Recruiting

Memory Enriched T Cells Following Stem Cell Transplant in Treating Patients With Recurrent B-Cell Non-Hodgkin Lymphoma

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Research Network

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