Key Insights

Highlights

Success Rate

70% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 37/100

Termination Rate

9.4%

3 terminated out of 32 trials

Success Rate

70.0%

-16.5% vs benchmark

Late-Stage Pipeline

3%

1 trials in Phase 3/4

Results Transparency

143%

10 of 7 completed with results

Key Signals

10 with results70% success

Data Visualizations

Phase Distribution

30Total
Not Applicable (4)
Early P 1 (4)
P 1 (8)
P 2 (13)
P 3 (1)

Trial Status

Active Not Recruiting9
Completed7
Unknown5
Recruiting5
Terminated3
Not Yet Recruiting2

Trial Success Rate

70.0%

Benchmark: 86.5%

Based on 7 completed trials

Clinical Trials (32)

Showing 20 of 20 trials
NCT02465060Phase 2Active Not Recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

NCT05859334Phase 2RecruitingPrimary

Testing the Anti-cancer Drug Erdafitinib for Brain Cancers That Have Returned or Progressed Following Treatment

NCT03213704Phase 2Active Not Recruiting

Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial)

NCT05676489Early Phase 1Not Yet Recruiting

MeFAMP for Imaging System A Amino Acid Transport in Primary and Metastatic Brain Tumors

NCT06397560Not ApplicableRecruiting

PrOton Pulsed reduCed dOse Rate Radiotherapy for Recurrent CNS maligNancies Trial

NCT03155620Phase 2Active Not Recruiting

Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

NCT03698994Phase 2Active Not Recruiting

Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)

NCT07553520Not ApplicableWithdrawn

Dietary Cysteine and Methionine Deprivation (CMD) in Glioma Patients

NCT07541781Phase 1Not Yet Recruiting

Sitagliptin in Recurrent/Progressive Grade 4 Glioma

NCT03213678Phase 2Completed

Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial)

NCT03213665Phase 2Completed

Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial)

NCT07074756Not ApplicableRecruiting

A Digital Treatment Platform for the Delivery of Home-Based Sequential Therapy in Patients With Glioma

NCT03796273Early Phase 1Terminated

Ketoconazole Before Surgery in Treating Patients With Recurrent Glioma or Breast Cancer Brain Metastases

NCT03212274Phase 2Active Not Recruiting

Olaparib in Treating Patients With Advanced Glioma, Cholangiocarcinoma, or Solid Tumors With IDH1 or IDH2 Mutations

NCT05406700Early Phase 1Active Not Recruiting

Niraparib In Recurrent IDH 1/2 Gliomas

NCT05660369Phase 1Recruiting

CARv3-TEAM-E T Cells in Glioblastoma

NCT03389230Phase 1Active Not Recruiting

Memory-Enriched T Cells in Treating Patients With Recurrent or Refractory Grade III-IV Glioma

NCT05045027Early Phase 1Active Not Recruiting

Simultaneous Multinuclear Metabolic MRI in Newly Diagnosed or Recurrent Glioma

NCT04794972Phase 1RecruitingPrimary

A Study of GNC-039, a Tetra-specific Antibody, in Participants With Relapsed/Refractory or Metastatic Solid Tumors

NCT04740190Phase 2CompletedPrimary

Talazoparib - Carboplatin for Recurrent High-grade Glioma With DDRd

Scroll to load more

Research Network

Activity Timeline