Key Insights

Highlights

Success Rate

69% trial completion

Published Results

25 trials with published results (32%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 47/100

Termination Rate

14.1%

11 terminated out of 78 trials

Success Rate

69.4%

-17.1% vs benchmark

Late-Stage Pipeline

1%

1 trials in Phase 3/4

Results Transparency

100%

25 of 25 completed with results

Key Signals

25 with results69% success11 terminated

Data Visualizations

Phase Distribution

76Total
Early P 1 (4)
P 1 (45)
P 2 (26)
P 3 (1)

Trial Status

Completed25
Recruiting19
Active Not Recruiting16
Terminated11
Withdrawn5
Unknown1

Trial Success Rate

69.4%

Benchmark: 86.5%

Based on 25 completed trials

Clinical Trials (78)

Showing 20 of 20 trials
NCT03259503Phase 1CompletedPrimary

Olaparib and High-Dose Chemotherapy in Treating Patients With Relapsed or Refractory Lymphomas Undergoing Stem Cell Transplant

NCT07098364Phase 1RecruitingPrimary

ST-067 in Combination With CD19-Directed CAR T-Cell Therapy (Liso-cel) in Relapsed/Refractory Large B-Cell Lymphoma

NCT05052528Phase 1RecruitingPrimary

Fludarabine and Cyclophosphamide With or Without Rituximab Before CD19 Chimeric Antigen Receptor T Cells for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma

NCT06649812Phase 2Recruiting

Testing the Effectiveness of a Combination Targeted Therapy (ViPOR) for Patients With Relapsed and/or Refractory Aggressive B-cell Lymphoma

NCT05077527Phase 1Recruiting

Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma

NCT05672251Phase 2RecruitingPrimary

Loncastuximab Tesirine and Mosunetuzumab for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma

NCT06854159Phase 2RecruitingPrimary

Odronextamab for the Treatment of Relapsed and Refractory Diffuse Large B-cell Lymphoma Before and After Chimeric Antigen Receptor T-cell Therapy

NCT06905509Phase 2RecruitingPrimary

Epcoritamab Plus Standard of Care Platinum-Based Chemotherapy and Autologous Hematopoietic Cell Transplant for the Treatment of Relapsed or Refractory Large B-cell Lymphoma

NCT07676877Phase 1Not Yet RecruitingPrimary

Lymphodepletion With Low Dose Total Body Irradiation Before Standard of Care Tisagenlecleucel for the Treatment of Relapsed and Recurrent Large B-cell Lymphoma

NCT04205409Phase 2Completed

Nivolumab for Relapsed, Refractory, or Detectable Disease Post Chimeric Antigen Receptor T-cell Treatment in Patients With Hematologic Malignancies

NCT03277729Phase 1Active Not Recruiting

A Phase I/II Study to Evaluate the Safety of Cellular Immunotherapy Using Autologous T Cells Engineered to Express a CD20-Specific Chimeric Antigen Receptor for Patients With Relapsed or Refractory B Cell Non-Hodgkin Lymphomas

NCT05453396Phase 2Terminated

Loncastuximab Tesirine for the Treatment of Relapsed or Refractory B-Cell Malignancies

NCT03321643Phase 1Active Not RecruitingPrimary

Testing the Addition of an Immunotherapy Agent, Atezolizumab, When Given With the Usual Chemo-Immunotherapy Drug Combination (Rituximab Plus Gemcitabine and Oxaliplatin) for Relapsed/Refractory (That Has Come Back or Not Responded to Treatment) Transformed Diffuse Large B-Cell Lymphoma

NCT06536049Phase 1RecruitingPrimary

Epcoritamab Plus Ibrutinib for the Treatment of Relapsed or Refractory Aggressive B-Cell Non-Hodgkin Lymphoma

NCT01955499Phase 1Active Not RecruitingPrimary

Lenalidomide and Ibrutinib in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

NCT05272384Phase 1Recruiting

Testing the Combination of Nivolumab and ASTX727 for Relapsed or Refractory B-Cell Lymphoma

NCT03038672Phase 2Active Not Recruiting

Nivolumab With or Without Varlilumab in Treating Patients With Relapsed or Refractory Aggressive B-cell Lymphomas

NCT06784726Phase 2RecruitingPrimary

Odronextamab for Relapsed and Refractory Large B-cell Lymphomas Before CAR-T

NCT03035331Phase 1Completed

Dendritic Cell Therapy, Cryosurgery, and Pembrolizumab in Treating Patients With Non-Hodgkin Lymphoma

NCT03479268Phase 1Active Not Recruiting

Pevonedistat and Ibrutinib in Treating Participants With Relapsed or Refractory CLL or Non-Hodgkin Lymphoma

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