Key Insights

Highlights

Success Rate

71% trial completion

Published Results

26 trials with published results (33%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 47/100

Termination Rate

13.9%

11 terminated out of 79 trials

Success Rate

71.1%

-15.5% vs benchmark

Late-Stage Pipeline

1%

1 trials in Phase 3/4

Results Transparency

96%

26 of 27 completed with results

Key Signals

26 with results71% success11 terminated

Data Visualizations

Phase Distribution

77Total
Early P 1 (4)
P 1 (45)
P 2 (27)
P 3 (1)

Trial Status

Completed27
Recruiting19
Active Not Recruiting14
Terminated11
Withdrawn5
Not Yet Recruiting1

Trial Success Rate

71.1%

Benchmark: 86.6%

Based on 27 completed trials

Clinical Trials (79)

Showing 20 of 20 trials
NCT03440567Phase 1CompletedPrimary

Avelumab, Utomilumab, Rituximab, Ibrutinib, and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma or Mantle Cell Lymphoma

NCT02153580Phase 1Active Not Recruiting

Cellular Immunotherapy Following Chemotherapy in Treating Patients With Recurrent Non-Hodgkin Lymphomas, Chronic Lymphocytic Leukemia, or B-Cell Prolymphocytic Leukemia

NCT07763210Phase 2Recruiting

Intrathecal Cytarabine and Hydrocortisone for the Early Treatment of ICANS in Patients Undergoing CAR T Therapy for Non Hodgkin Lymphoma

NCT06649812Phase 2Recruiting

Testing the Effectiveness of a Combination Targeted Therapy (ViPOR) for Patients With Relapsed and/or Refractory Aggressive B-cell Lymphoma

NCT03418038Phase 2Recruiting

Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic Leukemia

NCT02992522Phase 1Active Not Recruiting

Obinutuzumab, Venetoclax, and Lenalidomide in Treating Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma

NCT03015896Phase 1Completed

Nivolumab and Lenalidomide in Treating Patients With Relapsed or Refractory Non-Hodgkin or Hodgkin Lymphoma

NCT05359211Phase 1CompletedPrimary

NKTR-255 in Combination With CAR-T Cell Therapy for the Treatment of Relapsed or Refractory Large B-cell Lymphoma

NCT04665765Phase 2Active Not Recruiting

Polatuzumab Vedotin, Rituximab, Ifosfamide, Carboplatin, and Etoposide (PolaR-ICE) as Initial Salvage Therapy for the Treatment of Relapsed/Refractory Diffuse Large B-Cell Lymphoma

NCT07098364Phase 1SuspendedPrimary

ST-067 in Combination With CD19-Directed CAR T-Cell Therapy (Liso-cel) in Relapsed/Refractory Large B-Cell Lymphoma

NCT05272384Phase 1Recruiting

Testing the Combination of Nivolumab and ASTX727 for Relapsed or Refractory B-Cell Lymphoma

NCT06784726Phase 2RecruitingPrimary

Odronextamab for Relapsed and Refractory Large B-cell Lymphomas Before CAR-T

NCT01959698Phase 1Active Not Recruiting

Carfilzomib, Rituximab, Ifosfamide, Carboplatin, and Etoposide in Treating Patients With Relapsed or Refractory Stage I-IV Diffuse Large B-cell Lymphoma

NCT06536049Phase 1RecruitingPrimary

Epcoritamab Plus Ibrutinib for the Treatment of Relapsed or Refractory Aggressive B-Cell Non-Hodgkin Lymphoma

NCT03150329Phase 1Active Not Recruiting

Pembrolizumab and Vorinostat in Patients With Relapsed or Refractory DLBCL, FCL or HL.

NCT04007029Phase 1Active Not Recruiting

Modified Immune Cells (CD19/CD20 CAR-T Cells) in Treating Patients With Recurrent or Refractory B-Cell Lymphoma or Chronic Lymphocytic Leukemia

NCT05075603Phase 1Completed

Relapsed/Refractory Large B-cell Lymphoma With NT-I7 Post-CD19 CAR T-cell Therapy

NCT03259503Phase 1CompletedPrimary

Olaparib and High-Dose Chemotherapy in Treating Patients With Relapsed or Refractory Lymphomas Undergoing Stem Cell Transplant

NCT05052528Phase 1RecruitingPrimary

Fludarabine and Cyclophosphamide With or Without Rituximab Before CD19 Chimeric Antigen Receptor T Cells for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma

NCT05077527Phase 1Recruiting

Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma

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