Key Insights

Highlights

Success Rate

89% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 60/100

Termination Rate

10.3%

3 terminated out of 29 trials

Success Rate

88.9%

+2.4% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

21%

5 of 24 completed with results

Key Signals

5 with results89% success

Data Visualizations

Phase Distribution

28Total
Not Applicable (1)
P 1 (20)
P 2 (7)

Trial Status

Completed24
Terminated3
Active Not Recruiting1
Withdrawn1

Trial Success Rate

88.9%

Benchmark: 86.5%

Based on 24 completed trials

Clinical Trials (29)

Showing 20 of 20 trials
NCT03210714Phase 2Active Not Recruiting

Erdafitinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With FGFR Mutations (A Pediatric MATCH Treatment Trial)

NCT00638898Phase 1Completed

Busulfan, Melphalan, Topotecan Hydrochloride, and a Stem Cell Transplant in Treating Patients With Newly Diagnosed or Relapsed Solid Tumor

NCT02444546Phase 1Completed

Wild-Type Reovirus in Combination With Sargramostim in Treating Younger Patients With High-Grade Relapsed or Refractory Brain Tumors

NCT02255461Phase 1Terminated

Palbociclib Isethionate in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors

NCT02271711Phase 1CompletedPrimary

Expanded Natural Killer Cell Infusion in Treating Younger Patients With Recurrent/Refractory Brain Tumors

NCT02684071Phase 2TerminatedPrimary

Phase II Study of Intraventricular Methotrexate in Children With Recurrent or Progressive Malignant Brain Tumors

NCT00919750Completed

Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain Tumors

NCT00381797Phase 2Completed

Bevacizumab and Irinotecan in Treating Young Patients With Recurrent, Progressive, or Refractory Glioma, Medulloblastoma, Ependymoma, or Low Grade Glioma

NCT02194452Not ApplicableWithdrawn

Efficacy of 68Ga-DOTATOC Positron Emission Tomography (PET) CT in Children and Young Adults With Brain Tumors

NCT00326664Phase 1Completed

AZD2171 in Treating Young Patients With Recurrent, Progressive, or Refractory Primary CNS Tumors

NCT01239316Phase 2CompletedPrimary

Vismodegib in Treating Younger Patients With Recurrent or Refractory Medulloblastoma

NCT01088763Phase 1Terminated

Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia

NCT00946335Phase 1Completed

ABT-888 and Temozolomide in Treating Young Patients With Recurrent or Refractory CNS Tumors

NCT00217412Phase 1Completed

Vorinostat With or Without Isotretinoin in Treating Young Patients With Recurrent or Refractory Solid Tumors, Lymphoma, or Leukemia

NCT00095940Phase 1Completed

Lapatinib in Treating Young Patients With Recurrent or Refractory Central Nervous System Tumors

NCT00822458Phase 1CompletedPrimary

GDC-0449 in Treating Young Patients With Medulloblastoma That is Recurrent or Did Not Respond to Previous Treatment

NCT00070525Phase 2Completed

Tipifarnib in Treating Young Patients With Recurrent or Progressive High-Grade Glioma, Medulloblastoma, Primitive Neuroectodermal Tumor, or Brain Stem Glioma

NCT00100880Phase 1Completed

Lenalidomide in Treating Young Patients With Recurrent, Progressive, or Refractory CNS Tumors

NCT00063973Phase 1Completed

Cilengitide in Treating Children With Refractory Primary Brain Tumors

NCT00052780Phase 1Completed

Temozolomide and O6-Benzylguanine in Treating Children With Recurrent Brain Tumors

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