Key Insights

Highlights

Success Rate

86% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

13.6%

3 terminated out of 22 trials

Success Rate

85.7%

-0.8% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

22%

4 of 18 completed with results

Key Signals

4 with results86% success

Data Visualizations

Phase Distribution

22Total
Not Applicable (2)
P 1 (17)
P 2 (3)

Trial Status

Completed18
Terminated3
Withdrawn1

Trial Success Rate

85.7%

Benchmark: 86.5%

Based on 18 completed trials

Clinical Trials (22)

Showing 20 of 20 trials
NCT00638898Phase 1Completed

Busulfan, Melphalan, Topotecan Hydrochloride, and a Stem Cell Transplant in Treating Patients With Newly Diagnosed or Relapsed Solid Tumor

NCT02415153Phase 1Completed

Pomalidomide in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors

NCT02255461Phase 1Terminated

Palbociclib Isethionate in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors

NCT00381797Phase 2Completed

Bevacizumab and Irinotecan in Treating Young Patients With Recurrent, Progressive, or Refractory Glioma, Medulloblastoma, Ependymoma, or Low Grade Glioma

NCT02194452Not ApplicableWithdrawn

Efficacy of 68Ga-DOTATOC Positron Emission Tomography (PET) CT in Children and Young Adults With Brain Tumors

NCT02175745Not ApplicableTerminated

18F-FDOPA PET/CT or PET/MRI in Measuring Tumors in Patients With Newly-Diagnosed or Recurrent Gliomas

NCT00326664Phase 1Completed

AZD2171 in Treating Young Patients With Recurrent, Progressive, or Refractory Primary CNS Tumors

NCT01088763Phase 1Terminated

Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia

NCT00946335Phase 1Completed

ABT-888 and Temozolomide in Treating Young Patients With Recurrent or Refractory CNS Tumors

NCT00095940Phase 1Completed

Lapatinib in Treating Young Patients With Recurrent or Refractory Central Nervous System Tumors

NCT00070525Phase 2Completed

Tipifarnib in Treating Young Patients With Recurrent or Progressive High-Grade Glioma, Medulloblastoma, Primitive Neuroectodermal Tumor, or Brain Stem Glioma

NCT00063973Phase 1Completed

Cilengitide in Treating Children With Refractory Primary Brain Tumors

NCT00052780Phase 1Completed

Temozolomide and O6-Benzylguanine in Treating Children With Recurrent Brain Tumors

NCT00929903Phase 1Completed

Pazopanib Hydrochloride in Treating Young Patients With Solid Tumors That Have Relapsed or Not Responded to Treatment

NCT00012181Phase 1CompletedPrimary

Flavopiridol in Treating Children With Relapsed or Refractory Solid Tumors or Lymphomas

NCT00994500Phase 1Completed

Vorinostat and Bortezomib in Treating Young Patients With Refractory or Recurrent Solid Tumors, Including Central Nervous System Tumors and Lymphoma

NCT00101270Phase 1Completed

Oxaliplatin and Irinotecan in Treating Young Patients With Refractory Solid Tumors or Lymphomas

NCT00091182Phase 2Completed

Oxaliplatin in Treating Young Patients With Recurrent Solid Tumors That Have Not Responded to Previous Treatment

NCT01076530Phase 1Completed

Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors

NCT00281944Phase 1Completed

Combination Chemotherapy in Treating Young Patients With Advanced Solid Tumors

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