Key Insights

Highlights

Success Rate

77% trial completion

Published Results

42 trials with published results (43%)

Research Maturity

69 completed trials (70% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 74/100

Termination Rate

21.4%

21 terminated out of 98 trials

Success Rate

76.7%

-9.8% vs benchmark

Late-Stage Pipeline

1%

1 trials in Phase 3/4

Results Transparency

61%

42 of 69 completed with results

Key Signals

42 with results77% success21 terminated

Data Visualizations

Phase Distribution

97Total
Not Applicable (11)
Early P 1 (2)
P 1 (53)
P 2 (30)
P 3 (1)

Trial Status

Completed69
Terminated21
Withdrawn4
Active Not Recruiting3
Recruiting1

Trial Success Rate

76.7%

Benchmark: 86.5%

Based on 69 completed trials

Clinical Trials (98)

Showing 20 of 20 trials
NCT03504644Phase 1Active Not RecruitingPrimary

Venetoclax and Vincristine in Treating Patients With Relapsed or Refractory T-cell or B-cell Acute Lymphoblastic Leukemia

NCT03136146Phase 2Recruiting

Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma, Burkitt Lymphoma/Leukemia, or Double-Hit Lymphoma/Leukemia

NCT01199562Active Not Recruiting

Infection Prophylaxis and Management in Treating Cytomegalovirus (CMV) Infection in Patients With Hematologic Malignancies Previously Treated With Donor Stem Cell Transplant

NCT01815749Phase 1Active Not Recruiting

Genetically Modified T-cell Infusion Following Peripheral Blood Stem Cell Transplant in Treating Patients With Recurrent or High-Risk Non-Hodgkin Lymphoma

NCT05032183Phase 1TerminatedPrimary

Tagraxofusp and Low-Intensity Chemotherapy for the Treatment of CD123 Positive Relapsed or Refractory Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

NCT01588015Phase 1Completed

Vaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing Donor Stem Cell Transplant

NCT01769222Phase 1Terminated

Ipilimumab and Local Radiation for Selected Solid Tumors

NCT01523223Phase 1Completed

Donor Peripheral Stem Cell Transplant in Treating Patients With Hematolymphoid Malignancies

NCT01044745Phase 2Terminated

Rituximab in Preventing Acute Graft-Versus-Host Disease in a Donor Stem Cell Transplant for Hematologic Cancer

NCT01261247Phase 2Completed

Panobinostat in Treating Patients With Relapsed or Refractory Non-Hodgkin Lymphoma

NCT01805037Phase 1Terminated

Brentuximab Vedotin + Rituximab as Frontline Therapy for Pts w/ CD30+ and/or EBV+ Lymphomas

NCT02037256Not ApplicableCompleted

Bortezomib and Filgrastim to Promote Stem Cell Mobilization in Patients With Non-Hodgkin Lymphoma or Multiple Myeloma

NCT00536601Not ApplicableCompleted

High-Dose Chemotherapy With or Without Total-Body Irradiation Followed by Autologous Stem Cell Transplant in Treating Patients With Hematologic Cancer or Solid Tumors

NCT01678443Phase 1Terminated

Monoclonal Antibody Therapy Before Stem Cell Transplant in Treating Patients With Relapsed or Refractory Lymphoid Malignancies

NCT00489203Phase 2Completed

Beclomethasone Dipropionate in Preventing Acute Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer

NCT01258998Phase 2Completed

Study of Akt Inhibitor MK2206 in Patients With Relapsed Lymphoma

NCT01658007Early Phase 1Terminated

Pilot Study Of Sirolimus Plus Multiagent Chemotherapy For Relapsed/Refractory Acute Lymphoblastic Leukemia/Lymphoma

NCT00918333Phase 1Completed

Panobinostat and Everolimus in Treating Patients With Recurrent Multiple Myeloma, Non-Hodgkin Lymphoma, or Hodgkin Lymphoma

NCT00040846Phase 2Completed

Alemtuzumab, Fludarabine Phosphate, and Low-Dose Total Body Irradiation Before Donor Stem Cell Transplantation in Treating Patients With Hematological Malignancies

NCT00089011Phase 2Completed

Tacrolimus and Mycophenolate Mofetil in Preventing Graft-Versus-Host Disease in Patients Who Have Undergone Total-Body Irradiation With or Without Fludarabine Phosphate Followed by Donor Peripheral Blood Stem Cell Transplant for Hematologic Cancer

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Research Network

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