Key Insights

Highlights

Success Rate

85% trial completion

Published Results

44 trials with published results (48%)

Research Maturity

72 completed trials (79% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

14.3%

13 terminated out of 91 trials

Success Rate

84.7%

-1.8% vs benchmark

Late-Stage Pipeline

1%

1 trials in Phase 3/4

Results Transparency

61%

44 of 72 completed with results

Key Signals

44 with results85% success13 terminated

Data Visualizations

Phase Distribution

90Total
Not Applicable (9)
Early P 1 (1)
P 1 (49)
P 2 (30)
P 3 (1)

Trial Status

Completed72
Terminated13
Withdrawn3
Active Not Recruiting2
Unknown1

Trial Success Rate

84.7%

Benchmark: 86.5%

Based on 72 completed trials

Clinical Trials (91)

Showing 20 of 20 trials
NCT01384513Phase 2Completed

A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies

NCT01199562Active Not Recruiting

Infection Prophylaxis and Management in Treating Cytomegalovirus (CMV) Infection in Patients With Hematologic Malignancies Previously Treated With Donor Stem Cell Transplant

NCT02797470Phase 1Active Not Recruiting

Gene Therapy in Treating Patients With Human Immunodeficiency Virus-Related Lymphoma Receiving Stem Cell Transplant

NCT01476839Phase 1CompletedPrimary

Radiolabeled Monoclonal Antibody Therapy and Combination Chemotherapy Before Stem Cell Transplant in Treating Patients With Primary Refractory or Relapsed Hodgkin Lymphoma

NCT01588015Phase 1Completed

Vaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing Donor Stem Cell Transplant

NCT02168140Phase 1Completed

CPI-613 and Bendamustine Hydrochloride in Treating Patients With Relapsed or Refractory T-Cell Non-Hodgkin Lymphoma or Hodgkin Lymphoma

NCT01523223Phase 1Completed

Donor Peripheral Stem Cell Transplant in Treating Patients With Hematolymphoid Malignancies

NCT01535924Phase 1Completed

Gemcitabine and Bendamustine in Patients With Relapsed or Refractory Hodgkin's Lymphoma

NCT01780662Phase 1CompletedPrimary

Brentuximab Vedotin and Gemcitabine Hydrochloride in Treating Younger Patients With Relapsed or Refractory Hodgkin Lymphoma

NCT01805037Phase 1Terminated

Brentuximab Vedotin + Rituximab as Frontline Therapy for Pts w/ CD30+ and/or EBV+ Lymphomas

NCT00536601Not ApplicableCompleted

High-Dose Chemotherapy With or Without Total-Body Irradiation Followed by Autologous Stem Cell Transplant in Treating Patients With Hematologic Cancer or Solid Tumors

NCT01678443Phase 1Terminated

Monoclonal Antibody Therapy Before Stem Cell Transplant in Treating Patients With Relapsed or Refractory Lymphoid Malignancies

NCT00381940Phase 2Completed

Bortezomib, Ifosfamide, and Vinorelbine Tartrate in Treating Young Patients With Hodgkin's Lymphoma That is Recurrent or Did Not Respond to Previous Therapy

NCT00489203Phase 2Completed

Beclomethasone Dipropionate in Preventing Acute Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer

NCT01258998Phase 2Completed

Study of Akt Inhibitor MK2206 in Patients With Relapsed Lymphoma

NCT01075321Phase 1Completed

Everolimus and Lenalidomide in Treating Patients With Relapsed or Refractory Non-Hodgkin or Hodgkin Lymphoma

NCT00082888Phase 2Completed

Tipifarnib in Treating Patients With Relapsed or Refractory Lymphoma

NCT00918333Phase 1Completed

Panobinostat and Everolimus in Treating Patients With Recurrent Multiple Myeloma, Non-Hodgkin Lymphoma, or Hodgkin Lymphoma

NCT00005803Phase 1Completed

Autologous Stem Cell Transplant Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory Lymphoma

NCT00089011Phase 2Completed

Tacrolimus and Mycophenolate Mofetil in Preventing Graft-Versus-Host Disease in Patients Who Have Undergone Total-Body Irradiation With or Without Fludarabine Phosphate Followed by Donor Peripheral Blood Stem Cell Transplant for Hematologic Cancer

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Research Network

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