Key Insights

Highlights

Success Rate

76% trial completion

Published Results

30 trials with published results (45%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 74/100

Termination Rate

22.4%

15 terminated out of 67 trials

Success Rate

75.8%

-10.7% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

64%

30 of 47 completed with results

Key Signals

30 with results76% success15 terminated

Data Visualizations

Phase Distribution

66Total
Not Applicable (7)
Early P 1 (1)
P 1 (36)
P 2 (22)

Trial Status

Completed47
Terminated15
Withdrawn3
Active Not Recruiting2

Trial Success Rate

75.8%

Benchmark: 86.5%

Based on 47 completed trials

Clinical Trials (67)

Showing 20 of 20 trials
NCT01384513Phase 2Completed

A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies

NCT01199562Active Not Recruiting

Infection Prophylaxis and Management in Treating Cytomegalovirus (CMV) Infection in Patients With Hematologic Malignancies Previously Treated With Donor Stem Cell Transplant

NCT01815749Phase 1Active Not Recruiting

Genetically Modified T-cell Infusion Following Peripheral Blood Stem Cell Transplant in Treating Patients With Recurrent or High-Risk Non-Hodgkin Lymphoma

NCT01769222Phase 1Terminated

Ipilimumab and Local Radiation for Selected Solid Tumors

NCT01523223Phase 1Completed

Donor Peripheral Stem Cell Transplant in Treating Patients With Hematolymphoid Malignancies

NCT01044745Phase 2Terminated

Rituximab in Preventing Acute Graft-Versus-Host Disease in a Donor Stem Cell Transplant for Hematologic Cancer

NCT01805037Phase 1Terminated

Brentuximab Vedotin + Rituximab as Frontline Therapy for Pts w/ CD30+ and/or EBV+ Lymphomas

NCT02037256Not ApplicableCompleted

Bortezomib and Filgrastim to Promote Stem Cell Mobilization in Patients With Non-Hodgkin Lymphoma or Multiple Myeloma

NCT00536601Not ApplicableCompleted

High-Dose Chemotherapy With or Without Total-Body Irradiation Followed by Autologous Stem Cell Transplant in Treating Patients With Hematologic Cancer or Solid Tumors

NCT01678443Phase 1Terminated

Monoclonal Antibody Therapy Before Stem Cell Transplant in Treating Patients With Relapsed or Refractory Lymphoid Malignancies

NCT00489203Phase 2Completed

Beclomethasone Dipropionate in Preventing Acute Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer

NCT01258998Phase 2Completed

Study of Akt Inhibitor MK2206 in Patients With Relapsed Lymphoma

NCT00040846Phase 2Completed

Alemtuzumab, Fludarabine Phosphate, and Low-Dose Total Body Irradiation Before Donor Stem Cell Transplantation in Treating Patients With Hematological Malignancies

NCT00089011Phase 2Completed

Tacrolimus and Mycophenolate Mofetil in Preventing Graft-Versus-Host Disease in Patients Who Have Undergone Total-Body Irradiation With or Without Fludarabine Phosphate Followed by Donor Peripheral Blood Stem Cell Transplant for Hematologic Cancer

NCT00014235Not ApplicableCompleted

Fludarabine Phosphate and Total-Body Radiation Followed by Donor Peripheral Blood Stem Cell Transplant and Immunosuppression in Treating Patients With Hematologic Malignancies

NCT00006251Phase 1Completed

Fludarabine Phosphate, Low-Dose Total-Body Irradiation, and Donor Stem Cell Transplant Followed by Cyclosporine, Mycophenolate Mofetil, Donor Lymphocyte Infusion in Treating Patients With Hematopoietic Cancer

NCT00078858Phase 1Completed

Mycophenolate Mofetil and Cyclosporine in Reducing Graft-Versus-Host Disease in Patients With Hematologic Malignancies or Metastatic Kidney Cancer Undergoing Donor Stem Cell Transplant

NCT00003196Not ApplicableCompleted

Low-Dose Total Body Irradiation and Donor Peripheral Blood Stem Cell Transplant Followed by Donor Lymphocyte Infusion in Treating Patients With Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, or Multiple Myeloma

NCT01326702Phase 1Completed

Veliparib, Bendamustine Hydrochloride, and Rituximab in Treating Patients With Relapsed or Refractory Lymphoma, Multiple Myeloma, or Solid Tumors

NCT00856388Not ApplicableCompleted

Fludarabine Phosphate, Melphalan, Total-Body Irradiation, Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Bone Marrow Failure Disorders

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