Key Insights

Highlights

Success Rate

73% trial completion

Published Results

30 trials with published results (58%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

25.0%

13 terminated out of 52 trials

Success Rate

73.5%

-13.0% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

83%

30 of 36 completed with results

Key Signals

30 with results73% success13 terminated

Data Visualizations

Phase Distribution

51Total
Not Applicable (4)
Early P 1 (1)
P 1 (23)
P 2 (23)

Trial Status

Completed36
Terminated13
Withdrawn2
Recruiting1

Trial Success Rate

73.5%

Benchmark: 86.5%

Based on 36 completed trials

Clinical Trials (52)

Showing 20 of 20 trials
NCT03890952Phase 2CompletedPrimary

Translational Study of Nivolumab in Combination With Bevacizumab for Recurrent Glioblastoma

NCT02186509Phase 1Completed

Alisertib and Fractionated Stereotactic Radiosurgery in Treating Patients With Recurrent High Grade Gliomas

NCT00638898Phase 1Completed

Busulfan, Melphalan, Topotecan Hydrochloride, and a Stem Cell Transplant in Treating Patients With Newly Diagnosed or Relapsed Solid Tumor

NCT01894061Phase 2Completed

NovoTTF-100A With Bevacizumab (Avastin) in Patients With Recurrent Glioblastoma

NCT01814813Phase 2Terminated

Vaccine Therapy With Bevacizumab Versus Bevacizumab Alone in Treating Patients With Recurrent Glioblastoma Multiforme That Can Be Removed by Surgery

NCT06273176Recruiting

The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma

NCT01730950Phase 2Completed

Bevacizumab With or Without Radiation Therapy in Treating Patients With Recurrent Glioblastoma

NCT02015819Phase 1Completed

Genetically Modified Neural Stem Cells, Flucytosine, and Leucovorin for Treating Patients With Recurrent High-Grade Gliomas

NCT01125046Phase 2Completed

Bevacizumab in Treating Patients With Recurrent or Progressive Meningiomas

NCT01024907Phase 1Completed

Proton Beam Radiation Therapy in Treating Patients With Low Grade Gliomas

NCT01635283Phase 2Completed

Vaccine for Patients With Newly Diagnosed or Recurrent Low-Grade Glioma

NCT01806675Phase 1Completed

18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapy

NCT01103375Phase 1Terminated

Erlotinib Hydrochloride and Isotretinoin in Treating Patients With Recurrent Malignant Glioma

NCT01575275Phase 2Terminated

Aminolevulinic Acid in Visualizing a Tumor During Surgery in Patients With Glioblastoma Multiforme

NCT01234805Not ApplicableTerminated

Yoga Therapy in Treating Patients With Malignant Brain Tumors

NCT00335764Phase 1Completed

Sorafenib Combined With Erlotinib, Tipifarnib, or Temsirolimus in Treating Patients With Recurrent Glioblastoma Multiforme or Gliosarcoma

NCT01644955Phase 1Completed

Carboplatin in Treating Patients With Recurrent High-Grade Gliomas

NCT01234740Phase 1Completed

Bafetinib in Treating Patients With Recurrent High-Grade Glioma or Brain Metastases

NCT01342757Not ApplicableCompleted

Magnetic Resonance Spectroscopy Imaging in Predicting Response to Vorinostat and Temozolomide in Patients With Recurrent or Progressive Glioblastoma

NCT01753713Phase 2Completed

Dovitinib in Treating Patients With Recurrent or Progressive Glioblastoma

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Research Network

Activity Timeline