Key Insights

Highlights

Success Rate

78% trial completion

Published Results

73 trials with published results (39%)

Research Maturity

131 completed trials (70% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

19.4%

36 terminated out of 186 trials

Success Rate

78.4%

-8.1% vs benchmark

Late-Stage Pipeline

2%

4 trials in Phase 3/4

Results Transparency

56%

73 of 131 completed with results

Key Signals

73 with results78% success36 terminated

Data Visualizations

Phase Distribution

183Total
Not Applicable (13)
P 1 (106)
P 2 (60)
P 3 (4)

Trial Status

Completed131
Terminated36
Active Not Recruiting7
Withdrawn5
Recruiting4
Unknown2

Trial Success Rate

78.4%

Benchmark: 86.5%

Based on 131 completed trials

Clinical Trials (186)

Showing 20 of 20 trials
NCT02727803Phase 2Recruiting

Personalized NK Cell Therapy in CBT

NCT01384513Phase 2Completed

A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies

NCT00392353Phase 1Active Not Recruiting

Vorinostat and Azacitidine in Treating Patients With Myelodysplastic Syndromes or Acute Myeloid Leukemia

NCT01861314Phase 1Active Not Recruiting

Bortezomib, Sorafenib Tosylate, and Decitabine in Treating Patients With Acute Myeloid Leukemia

NCT03017820Phase 1Recruiting

A Vaccine (VSV-hIFNβ-NIS) With or Without Cyclophosphamide and Combinations of Ipilimumab, Nivolumab, and Cemiplimab in Treating Relapsed or Refractory Multiple Myeloma, Acute Myeloid Leukemia or Lymphoma

NCT02333162Phase 1Suspended

Intensity Modulated Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients With Relapsed Hematologic Cancers Undergoing a Second Donor Stem Cell Transplant

NCT05672147Phase 1Recruiting

CD33-CAR T Cell Therapy for the Treatment of Recurrent or Refractory Acute Myeloid Leukemia

NCT02381548Phase 1Terminated

Phase I Trial of AZD1775 and Belinostat in Treating Patients With Relapsed or Refractory Myeloid Malignancies or Untreated Acute Myeloid Leukemia

NCT01199562Active Not Recruiting

Infection Prophylaxis and Management in Treating Cytomegalovirus (CMV) Infection in Patients With Hematologic Malignancies Previously Treated With Donor Stem Cell Transplant

NCT01869114Phase 2Completed

Sirolimus and Azacitidine in Treating Patients With High Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia That is Recurrent or Not Eligible for Intensive Chemotherapy

NCT01139970Phase 1Completed

Veliparib and Temozolomide in Treating Patients With Acute Leukemia

NCT01760655Phase 2Completed

Reduced-Intensity Conditioning Before Donor Stem Cell Transplant in With High-Risk Hematologic Malignancies

NCT03513484Phase 1Active Not Recruiting

Nintedanib and Azacitidine in Treating Participants With HOX Gene Overexpression Relapsed or Refractory Acute Myeloid Leukemia

NCT02159495Phase 1Active Not Recruiting

Genetically Modified T-cell Immunotherapy in Treating Patients With Relapsed/Refractory Acute Myeloid Leukemia and Persistent/Recurrent Blastic Plasmacytoid Dendritic Cell Neoplasm

NCT02094794Phase 2Active Not Recruiting

Total Marrow and Lymphoid Irradiation and Chemotherapy Before DSCT in Treating Patients With High-Risk ALL or AML

NCT02446964Phase 1Completed

Total Marrow and Lymphoid Irradiation and Chemotherapy Before Donor Transplant in Treating Patients With Myelodysplastic Syndrome or Acute Leukemia

NCT03537599Phase 1Terminated

Daratumumab and Donor Lymphocyte Infusion in Treating Participants With Relapsed Acute Myeloid Leukemia After Stem Cell Transplant

NCT00588991Phase 1Completed

Veliparib and Topotecan With or Without Carboplatin in Treating Patients With Relapsed or Refractory Acute Leukemia, High-Risk Myelodysplasia, or Aggressive Myeloproliferative Disorders

NCT02204085Phase 1Active Not Recruiting

A Phase I/II Trial of the MUC1 Inhibitor, GO-203-2C in Patients With Relapsed or Refractory Acute Myeloid Leukemia

NCT02484391Phase 1Completed

CPI-613, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Granulocytic Sarcoma

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