Key Insights

Highlights

Success Rate

55% trial completion

Published Results

33 trials with published results (29%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 60/100

Termination Rate

18.3%

21 terminated out of 115 trials

Success Rate

55.3%

-31.3% vs benchmark

Late-Stage Pipeline

1%

1 trials in Phase 3/4

Results Transparency

127%

33 of 26 completed with results

Key Signals

33 with results55% success21 terminated

Data Visualizations

Phase Distribution

115Total
Not Applicable (1)
Early P 1 (1)
P 1 (81)
P 2 (31)
P 3 (1)

Trial Status

Recruiting32
Completed26
Terminated21
Active Not Recruiting20
Withdrawn11
Suspended3

Trial Success Rate

55.3%

Benchmark: 86.6%

Based on 26 completed trials

Clinical Trials (115)

Showing 20 of 20 trials
NCT06484062Phase 1Recruiting

Testing the Anti-cancer Drug, Cirtuvivint, and Its Combination With ASTX727 to Improve Outcomes in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndromes

NCT06763341Phase 1RecruitingPrimary

A Phase 1 Study of AOH1996 in Patients With Relapsed/Refractory Acute Myeloid Leukemia

NCT03629171Phase 2RecruitingPrimary

Liposome-encapsulated Daunorubicin-Cytarabine and Venetoclax in Treating Participants With Relapsed, Refractory or Untreated Acute Myeloid Leukemia

NCT03661307Phase 1Recruiting

Quizartinib, Decitabine, and Venetoclax in Treating Participants With Untreated or Relapsed Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome

NCT06871410Phase 1RecruitingPrimary

Genetically Engineered Cells (CD83 CAR T Cells) for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia

NCT03874052Phase 1Recruiting

Ruxolitinib in Combination With Venetoclax With and Without Azacitidine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

NCT07012044Phase 1Recruiting

A Study to Find the Highest Dose of Cedazuridine and Decitabine Combination With Filgrastim as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With High-Risk Acute Myeloid Leukemia

NCT05035706Early Phase 1Active Not Recruiting

Anti-Leukemia Immune Responses After Irradiation of Extramedullary Tumors

NCT02530034Phase 1Active Not Recruiting

Hu8F4 in Treating Patients With Advanced Hematologic Malignancies

NCT03214562Phase 1Recruiting

Venetoclax With Combination Chemotherapy in Treating Patients With Newly Diagnosed or Relapsed or Refractory Acute Myeloid Leukemia

NCT03630991Phase 1Recruiting

Edetate Calcium Disodium or Succimer in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Undergoing Chemotherapy

NCT04375631Phase 1RecruitingPrimary

CLAG-M or FLAG-Ida Chemotherapy and Reduced-Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelomonocytic Leukemia

NCT03816319Phase 1Active Not Recruiting

TAK-243 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndromes With Increased Blasts

NCT03471260Phase 1Recruiting

Ivosidenib and Venetoclax With or Without Azacitidine in Treating Patients With IDH1 Mutated Hematologic Malignancies

NCT03683433Phase 2Recruiting

Enasidenib and Azacitidine in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia and IDH2 Gene Mutation

NCT03953898Phase 2Active Not Recruiting

Using the Anticancer Drug Olaparib to Treat Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome With an Isocitrate Dehydrogenase (IDH) Mutation

NCT02890329Phase 1Active Not Recruiting

Ipilimumab and Decitabine in Treating Patients With Relapsed or Refractory Myelodysplastic Syndrome or Acute Myeloid Leukemia

NCT07022678Phase 3Recruiting

Xylitol Dental Wipes for the Reduction of Bloodstream Infection Risk in Children With Acute Myeloid Leukemia

NCT05010122Phase 1Recruiting

ASTX727, Venetoclax, and Gilteritinib for the Treatment of Newly Diagnosed, Relapsed or Refractory FLT3-Mutated Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

NCT04746235Phase 2Active Not Recruiting

Venetoclax and ASTX727 for the Treatment of Relapsed, Refractory, or Newly Diagnosed Acute Myeloid Leukemia

Scroll to load more

Research Network

Activity Timeline