Key Insights

Highlights

Success Rate

57% trial completion

Published Results

33 trials with published results (29%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 60/100

Termination Rate

17.4%

20 terminated out of 115 trials

Success Rate

56.5%

-30.0% vs benchmark

Late-Stage Pipeline

1%

1 trials in Phase 3/4

Results Transparency

127%

33 of 26 completed with results

Key Signals

33 with results57% success20 terminated

Data Visualizations

Phase Distribution

115Total
Not Applicable (1)
Early P 1 (1)
P 1 (81)
P 2 (31)
P 3 (1)

Trial Status

Recruiting30
Completed26
Active Not Recruiting20
Terminated20
Withdrawn11
Suspended5

Trial Success Rate

56.5%

Benchmark: 86.6%

Based on 26 completed trials

Clinical Trials (115)

Showing 20 of 20 trials
NCT06492707Phase 1Suspended

DR-18 to Prevent or Treat Acute Myeloid Leukemia or Myelodysplastic Syndrome Relapse After Hematopoietic Cell Transplantation, the DR. DREAM Trial

NCT02861417Phase 2Active Not Recruiting

Busulfan, Fludarabine Phosphate, and Post-Transplant Cyclophosphamide in Treating Patients With Blood Cancer Undergoing Donor Stem Cell Transplant

NCT02392572Phase 1Active Not Recruiting

ONC201 in Treating Patients With Relapsed or Refractory Acute Leukemia or High-Risk Myelodysplastic Syndrome

NCT07012044Phase 1Recruiting

A Study to Find the Highest Dose of Cedazuridine and Decitabine Combination With Filgrastim as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With High-Risk Acute Myeloid Leukemia

NCT06871410Phase 1RecruitingPrimary

Genetically Engineered Cells (CD83 CAR T Cells) for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia

NCT02727803Phase 2Recruiting

Personalized NK Cell Therapy in CBT

NCT04975919Phase 2Active Not Recruiting

Venetoclax in Combination With Decitabine and Cedazuridine for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia

NCT03816319Phase 1Recruiting

TAK-243 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndromes With Increased Blasts

NCT06763341Phase 1RecruitingPrimary

A Phase 1 Study of AOH1996 in Patients With Relapsed/Refractory Acute Myeloid Leukemia

NCT03672539Phase 2Completed

Liposome-encapsulated Daunorubicin-Cytarabine and Gemtuzumab Ozogamicin in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) or High Risk Myelodysplastic Syndrome

NCT07025564Phase 1SuspendedPrimary

MiRisten for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia

NCT03661307Phase 1Suspended

Quizartinib, Decitabine, and Venetoclax in Treating Participants With Untreated or Relapsed Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome

NCT05010122Phase 1Recruiting

ASTX727, Venetoclax, and Gilteritinib for the Treatment of Newly Diagnosed, Relapsed or Refractory FLT3-Mutated Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

NCT07022678Phase 3Recruiting

Xylitol Dental Wipes for the Reduction of Bloodstream Infection Risk in Children With Acute Myeloid Leukemia

NCT02530034Phase 1Active Not Recruiting

Hu8F4 in Treating Patients With Advanced Hematologic Malignancies

NCT03969446Phase 1Suspended

Pembrolizumab and Decitabine With or Without Venetoclax in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome That Is Newly-Diagnosed, Recurrent, or Refractory

NCT03874052Phase 1Recruiting

Ruxolitinib in Combination With Venetoclax With and Without Azacitidine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

NCT06399640Phase 1Recruiting

Eltanexor and Venetoclax in Relapsed or Refractory Myelodysplastic Syndrome and Acute Myeloid Leukemia

NCT03289910Phase 2Active Not Recruiting

Topotecan Hydrochloride and Carboplatin With or Without Veliparib in Treating Advanced Myeloproliferative Disorders and Acute Myeloid Leukemia or Chronic Myelomonocytic Leukemia

NCT03128034Phase 1Recruiting

211^At-BC8-B10 Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome, or Mixed-Phenotype Acute Leukemia

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