Key Insights

Highlights

Success Rate

72% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

10.2%

9 terminated out of 88 trials

Success Rate

71.9%

-14.7% vs benchmark

Late-Stage Pipeline

6%

5 trials in Phase 3/4

Results Transparency

43%

10 of 23 completed with results

Key Signals

10 with results72% success

Data Visualizations

Phase Distribution

66Total
Not Applicable (15)
Early P 1 (2)
P 1 (14)
P 2 (30)
P 3 (4)
P 4 (1)

Trial Status

Recruiting27
Completed23
Not Yet Recruiting12
Terminated9
Unknown8
Active Not Recruiting6

Trial Success Rate

71.9%

Benchmark: 86.6%

Based on 23 completed trials

Clinical Trials (88)

Showing 20 of 20 trials
NCT07143487Not ApplicableRecruiting

Family Communications After Genetic Testing

NCT06997497Phase 3Recruiting

A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

NCT06328361Not ApplicableRecruiting

Nordic ORgan Preservation Pilot Approach Nonrandomised Single-Arm Trial for Non-Operative Management of Rectal Cancer

NCT05081024RecruitingPrimary

Establishing a ctDNA Biomarker to Improve Organ Preserving Strategies in Patients With Rectal Cancer

NCT04165772Phase 2RecruitingPrimary

Study of Induction PD-1 Blockade in Subjects With Locally Advanced Mismatch Repair Deficient Solid Tumors

NCT05482516Phase 3Recruiting

Evaluating Novel Therapies in ctDNA Positive GI Cancers

NCT05059444Recruiting

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

NCT07802197Not ApplicableRecruitingPrimary

Neoadjuvant Radiotherapy vs Upfront Surgery in Locally Advanced Proximal Rectal Cancer

NCT07292298Phase 2RecruitingPrimary

Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

NCT02107105RecruitingPrimary

Evaluation of Quality of Life and Utilities Following Surgical Treatment of Stage I-IV Rectal Cancer

NCT07341126Not Yet Recruiting

Use of a Novel Camera to Check the Bowel After Polyp or Tumour Removal

NCT07765667Phase 2Not Yet RecruitingPrimary

NCT + PD1 + Ketogenic Diet and/or Vitamin C for LARC

NCT04104139Phase 1CompletedPrimary

TAS-102 With Concurrent Radiation for the Treatment of Untreated Resectable Stage II-III Rectal Cancer

NCT07209215Phase 2Not Yet RecruitingPrimary

ctDNA-Informed Management of Early-Stage Rectal Cancer

NCT06908031Phase 2CompletedPrimary

SCRT+mFOLFOX6+PD-1 Antibody and Targeted Therapy for High-Risk pMMR/MSS Rectal Cancer

NCT07695519Not Yet Recruiting

SCARLET - Italian proSpeCtionAl obseRvationaL multicEntre Study on Treatment for recTal pT1 Cancer

NCT07549399Phase 3RecruitingPrimary

SCRT + Chemo Targeted Immuno-neoadjuvant Therapy for High-risk pMMR/MSS RC

NCT06780787Phase 2RecruitingPrimary

FOLFOX, Botensilimab, and Balstilimab for the Treatment of Localized Rectal Cancer Before Surgery

NCT07669220Phase 2RecruitingPrimary

A Multicenter, Randomized Controlled Phase II Study of Short-Course Radiotherapy Followed by Sequential PD-1 Inhibitor and FOLFOX Chemotherapy Versus Long-Course Chemoradiotherapy for High-Risk Locally Advanced pMMR/MSS Lower Rectal Adenocarcinoma (STAR Trial)

NCT03594630Early Phase 1RecruitingPrimary

Active Surveillance and Chemotherapy Before Surgery in Treating Participants With Stage II-III Rectal Cancer

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