Key Insights

Highlights

Success Rate

93% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 40/100

Termination Rate

3.8%

1 terminated out of 26 trials

Success Rate

93.3%

+6.8% vs benchmark

Late-Stage Pipeline

23%

6 trials in Phase 3/4

Results Transparency

36%

5 of 14 completed with results

Key Signals

5 with results93% success

Data Visualizations

Phase Distribution

23Total
Not Applicable (1)
Early P 1 (1)
P 1 (13)
P 2 (2)
P 3 (6)

Trial Status

Completed14
Recruiting4
Unknown3
Active Not Recruiting3
Terminated1
Not Yet Recruiting1

Trial Success Rate

93.3%

Benchmark: 86.5%

Based on 14 completed trials

Clinical Trials (26)

Showing 20 of 20 trials
NCT06834035Phase 1Recruiting

Targeting Collagen VII Antibodies With IV IgG in Dystrophic Epidermolysis Bullosa

NCT07011589Phase 1Not Yet Recruiting

Targeting Collagen VII Antibodies in Bullous Diseases Using Efgartigimod IV (VYVGART)

NCT07193134Phase 1Recruiting

GMEB-SASS: A Gene-Modified Skin Substitute for RDEB Treatment

NCT04213261Phase 3Active Not RecruitingPrimary

A Study of FCX-007 for Recessive Dystrophic Epidermolysis Bullosa

NCT07016750Phase 3Recruiting

A Study Comparing KB803 and Matched Placebo in Patients With Dystrophic Epidermolysis Bullosa

NCT01874769CompletedPrimary

Study of Immune Tolerance and Capacity for Wound Healing of Patients With Recessive Dystrophic Epidermolysis Bullosa (RDEB)

NCT06713434Phase 1Active Not Recruiting

Pilot Study of ELK-003 Eye Drops for Treating Ocular Manifestations of Epidermolysis Bullosa

NCT05944250Not ApplicableCompletedPrimary

A Pilot Study to Evaluate a Temporary Skin Substitute (Spincare® Matrix) for Wound Healing in RDEB Patients

NCT04177498Early Phase 1CompletedPrimary

Rigosertib in Patients With Recessive Dystrophic Epidermolysis Bullosa Associated SCC

NCT05725018Phase 3Active Not Recruiting

A Phase 3b Study for the Treatment of Dystrophic Epidermolysis Bullosa (DEB) in New and Previously EB-101 Treated Patients

NCT04917874Phase 3Completed

A Long-term Treatment With B-VEC for Dystrophic Epidermolysis Bullosa

NCT04491604Phase 3Completed

Ph 3 Efficacy and Safety of B-VEC for the Treatment of DEB

NCT04227106Phase 3Completed

Phase 3, Open-label Clinical Trial of EB-101 for the Treatment of Recessive Dystrophic Epidermolysis Bullosa (RDEB)

NCT05143190Phase 2CompletedPrimary

Extension Study to PTR-01-002 (A Study in Recessive Dystrophic Epidermolysis Bullosa (RDEB) Patients Previously Treated With PTR-01)

NCT03392909Phase 1UnknownPrimary

Intravenous Gentamicin Therapy for Recessive Dystrophic Epidermolysis Bullosa (RDEB)

NCT03529877Phase 1CompletedPrimary

Allogeneic ABCB5-positive Stem Cells for Treatment of Epidermolysis Bullosa

NCT02984085Phase 1TerminatedPrimary

Clinical Trial to Assess Safety and Efficacy of Autologous Cultured Epidermal Grafts Containing Epidermal Stem Cells Genetically Modified in Patients With RDEB.

NCT04599881Phase 2CompletedPrimary

A Study of PTR-01 in Recessive Dystrophic Epidermolysis Bullosa

NCT04917887Recruiting

Long-Term Follow-up Protocol

NCT03752905Phase 1CompletedPrimary

A Phase 1/2 Trial of PTR-01 in Adult Patients With Recessive Dystrophic Epidermolysis Bullosa (RDEB)

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