Recessive Dystrophic Epidermolysis Bullosa
26
4
7
14
Key Insights
Highlights
Success Rate
93% trial completion (above average)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 40/100
3.8%
1 terminated out of 26 trials
93.3%
+6.8% vs benchmark
23%
6 trials in Phase 3/4
36%
5 of 14 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 14 completed trials
Clinical Trials (26)
Targeting Collagen VII Antibodies With IV IgG in Dystrophic Epidermolysis Bullosa
Targeting Collagen VII Antibodies in Bullous Diseases Using Efgartigimod IV (VYVGART)
GMEB-SASS: A Gene-Modified Skin Substitute for RDEB Treatment
A Study of FCX-007 for Recessive Dystrophic Epidermolysis Bullosa
A Study Comparing KB803 and Matched Placebo in Patients With Dystrophic Epidermolysis Bullosa
Study of Immune Tolerance and Capacity for Wound Healing of Patients With Recessive Dystrophic Epidermolysis Bullosa (RDEB)
Pilot Study of ELK-003 Eye Drops for Treating Ocular Manifestations of Epidermolysis Bullosa
A Pilot Study to Evaluate a Temporary Skin Substitute (Spincare® Matrix) for Wound Healing in RDEB Patients
Rigosertib in Patients With Recessive Dystrophic Epidermolysis Bullosa Associated SCC
A Phase 3b Study for the Treatment of Dystrophic Epidermolysis Bullosa (DEB) in New and Previously EB-101 Treated Patients
A Long-term Treatment With B-VEC for Dystrophic Epidermolysis Bullosa
Ph 3 Efficacy and Safety of B-VEC for the Treatment of DEB
Phase 3, Open-label Clinical Trial of EB-101 for the Treatment of Recessive Dystrophic Epidermolysis Bullosa (RDEB)
Extension Study to PTR-01-002 (A Study in Recessive Dystrophic Epidermolysis Bullosa (RDEB) Patients Previously Treated With PTR-01)
Intravenous Gentamicin Therapy for Recessive Dystrophic Epidermolysis Bullosa (RDEB)
Allogeneic ABCB5-positive Stem Cells for Treatment of Epidermolysis Bullosa
Clinical Trial to Assess Safety and Efficacy of Autologous Cultured Epidermal Grafts Containing Epidermal Stem Cells Genetically Modified in Patients With RDEB.
A Study of PTR-01 in Recessive Dystrophic Epidermolysis Bullosa
Long-Term Follow-up Protocol
A Phase 1/2 Trial of PTR-01 in Adult Patients With Recessive Dystrophic Epidermolysis Bullosa (RDEB)