Key Insights

Highlights

Success Rate

25% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 85/100

Termination Rate

17.6%

3 terminated out of 17 trials

Success Rate

25.0%

-61.5% vs benchmark

Late-Stage Pipeline

6%

1 trials in Phase 3/4

Results Transparency

0%

0 of 1 completed with results

Key Signals

25% success

Data Visualizations

Phase Distribution

14Total
P 1 (8)
P 2 (5)
P 3 (1)

Trial Status

Recruiting11
Terminated3
Unknown2
Completed1

Trial Success Rate

25.0%

Benchmark: 86.5%

Based on 1 completed trials

Clinical Trials (17)

Showing 17 of 17 trials
NCT06922591Phase 1Recruiting

Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients

NCT04678648Phase 1Recruiting

A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies

NCT06287463Phase 1Terminated

Study of DCC-3084 in Participants With Advanced Malignancies Driven by the Mitogen-Activated Protein Kinase (MAPK) Pathway

NCT07252479Phase 1Recruiting

Evaluation of RAS Inhibitor Treatment in Participants With Advanced or Metastatic Solid Tumors Harboring RAS Mutations

NCT04395495RecruitingPrimary

RASopathy Biorepository

NCT06299839Phase 1RecruitingPrimary

PAS-004 in Patients With Advanced Solid Tumors

NCT04776655Phase 3Recruiting

Study in mCRC Patients RAS/BRAF wt Tissue and RAS Mutated LIquid BIopsy to Compare FOLFIRI Plus CetuxiMAb or BevacizumaB

NCT07121829Phase 1Terminated

Tovorafenib (DAY101) or in Combination With Pimasertib for Participants With Melanoma and Other Solid Tumors

NCT05340621Phase 1CompletedPrimary

NAUTILUS: OKI-179 Plus Binimetinib in Patients with Advanced Solid Tumors in the RAS Pathway (Phase 1b) and NRAS-mutated Melanoma (Phase 2)

NCT05831995Phase 1Terminated

Safety and Effectiveness of ABM-168 in Adults with Advanced Solid Tumors.

NCT04286360RecruitingPrimary

Hematological Anomalies in Children With Rasopathy

NCT06206096Phase 2Recruiting

PD-1 Antibody Plus Bevacizumab and CAPOX as First-line Treatment for RAS-mut MSS mCRC

NCT06321081Phase 2RecruitingPrimary

ICE Study: Combination of Irinotecan Plus Cetuximab and Envafolimab as a Rechallenge Regimen in mCRC

NCT06229340Phase 2RecruitingPrimary

Leflunomide or Combination of MEK Inhibitor and Hydroxychloroquine for Refractory Patients With RAS Mutations

NCT06218810Phase 2Recruiting

Cadonilimab in Combination With Bevacizumab and FOLFOX Regimen for the First-Line Treatment of Advanced Unresectable MSS-Type, RAS-Mutated Metastatic Colorectal Cancer

NCT04194359Phase 2Unknown

Sintilimab (IBI308) Combined With Bevacizumab + XELOX Regimen in Metastatic Colorectal Cancer

NCT04852250Unknown

Centralized Tumour Board and Secondary Intervention Rate in mCRC

Showing all 17 trials

Research Network

Activity Timeline