Key Insights

Highlights

Success Rate

85% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 39/100

Termination Rate

7.3%

3 terminated out of 41 trials

Success Rate

85.0%

-1.5% vs benchmark

Late-Stage Pipeline

12%

5 trials in Phase 3/4

Results Transparency

59%

10 of 17 completed with results

Key Signals

10 with results85% success

Data Visualizations

Phase Distribution

31Total
Not Applicable (1)
P 1 (15)
P 2 (10)
P 3 (3)
P 4 (2)

Trial Status

Completed17
Recruiting9
Active Not Recruiting4
Withdrawn3
Terminated3
Unknown3

Trial Success Rate

85.0%

Benchmark: 86.5%

Based on 17 completed trials

Clinical Trials (41)

Showing 20 of 20 trials
NCT04868604Phase 1RecruitingPrimary

64Cu-SAR-bisPSMA and 67Cu-SAR-bisPSMA for Identification and Treatment of PSMA-expressing Metastatic Castrate Resistant Prostate Cancer (SECuRE)

NCT04597411Phase 1Active Not RecruitingPrimary

Study of 225Ac-PSMA-617 in Men With PSMA-positive Prostate Cancer

NCT06353386Phase 1RecruitingPrimary

Substudy 01A: Safety and Efficacy of Opevesostat (MK-5684)-Based Treatment Combinations or Opevesostat Alone in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-5684-01A)

NCT07225946Phase 3RecruitingPrimary

A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer

NCT03431350Phase 2Active Not RecruitingPrimary

A Study of Niraparib Combination Therapies for the Treatment of Metastatic Castration-Resistant Prostate Cancer

NCT06190899Phase 1Recruiting

Gedatolisib in Combination With Darolutamide in Metastatic Castration-Resistant Prostate Cancer

NCT06788509Phase 1Enrolling By Invitation

A Rollover Study for Continued Study Treatment and Ongoing Safety Monitoring

NCT02592317Phase 1Active Not RecruitingPrimary

A Study to Evaluate the Effect of Multiple Doses of JNJ-56021927 on the Pharmacokinetics of Multiple Cytochrome P450 and Transporter Substrates in Participants With Castration-Resistant Prostate Cancer

NCT05968599CompletedPrimary

A Study to Learn About the Study Medicines Called Enzalutamide and Abiraterone in People With Metastatic Castration-resistant Prostate Cancer

NCT07376057Not Yet RecruitingPrimary

Development and Prospective Validation of a Pathology-Based Artificial Intelligence Model for Predicting the Time to Castration Resistance of Prostate Cancer

NCT04717154Phase 2CompletedPrimary

Ipilimumab With Nivolumab for Molecular-selected Patients With Castration-resistant Prostate Cancer

NCT05743621Phase 1RecruitingPrimary

Study of TVB-2640 in Men With Metastatic Castration-Resistant Prostate Cancer

NCT04381832Phase 1CompletedPrimary

Adenosine Receptor Antagonist Combination Therapy for Metastatic Castrate Resistant Prostate Cancer

NCT02204072Phase 1CompletedPrimary

BI836845 Plus Enzalutamide in Castrate Resistant Prostate Cancer (CRPC)

NCT02803437CompletedPrimary

Drug Use Investigation of Xofigo, Castration Resistant Prostate Cancer With Bone Metastases

NCT05169684Phase 2TerminatedPrimary

A Study of BMS-986218 or BMS-986218 Plus Nivolumab in Combination With Docetaxel in Participants With Metastatic Castration-resistant Prostate Cancer

NCT05944237Phase 1Recruiting

HTL0039732 in Participants With Advanced Solid Tumours

NCT04104776Phase 1Recruiting

A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas

NCT03822845Phase 2Completed

Evaluating the Clinical Accuracy of Gallium-68 PSMA PET/CT Imaging in Patients With Biochemical Recurrence of Prostate Cancer

NCT04249947Phase 1TerminatedPrimary

P-PSMA-101 CAR-T Cells in the Treatment of Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC) and Advanced Salivary Gland Cancers (SGC)

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