Key Insights

Highlights

Success Rate

88% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Low Risk

Score: 15/100

Termination Rate

5.9%

1 terminated out of 17 trials

Success Rate

87.5%

+1.0% vs benchmark

Late-Stage Pipeline

18%

3 trials in Phase 3/4

Results Transparency

71%

5 of 7 completed with results

Key Signals

5 with results88% success

Data Visualizations

Phase Distribution

14Total
P 1 (5)
P 2 (6)
P 3 (2)
P 4 (1)

Trial Status

Completed7
Recruiting5
Unknown3
Terminated1
Active Not Recruiting1

Trial Success Rate

87.5%

Benchmark: 86.5%

Based on 7 completed trials

Clinical Trials (17)

Showing 17 of 17 trials
NCT07357727Phase 3RecruitingPrimary

A Phase 3 Study of Pelabresib (DAK539) and Ruxolitinib in Myelofibrosis (MF)

NCT07469891Phase 1Recruiting

A Phase 1 Study of PRT12396 in Participants With Select Myeloproliferative Neoplasms

NCT07340138Phase 1RecruitingPrimary

Study of Pelabresib add-on to Ruxolitinib in Japanese Adult Patients With Myelofibrosis

NCT03441113Phase 2Active Not Recruiting

Extended Access of Momelotinib in Adults With Myelofibrosis

NCT07362225Recruiting

MPN PROGRESSion Registry: Observational Study Tracking Symptoms, Treatments, and Disease Progression in People With Myeloproliferative Neoplasms (MPNs)

NCT07319026CompletedPrimary

Role of Myeloid-derived Suppressor Cells In Primary Myelofibrosis

NCT04745637UnknownPrimary

Managed Access Programs for INC424, Ruxolitinib

NCT06770842Phase 2RecruitingPrimary

Ropeginterferon Alfa 2b Plus Ruxolitinib for Myelofibrosis

NCT03136185Phase 1Completed

Bomedemstat (IMG-7289/MK-3543) in Participants With Myelofibrosis (IMG-7289-CTP-102/MK-3543-002)

NCT02515630Phase 2CompletedPrimary

Momelotinib in Transfusion-Dependent Adults With Primary Myelofibrosis (PMF) or Post-polycythemia Vera or Post-essential Thrombocythemia Myelofibrosis (Post-PV/ET MF)

NCT02101268Phase 3CompletedPrimary

Efficacy of Momelotinib Versus Best Available Therapy in Anemic or Thrombocytopenic Subjects With Primary Myelofibrosis (MF), Post-polycythemia Vera MF, or Post-essential Thrombocythemia MF

NCT03662126Phase 2UnknownPrimary

KRT-232 Versus Best Available Therapy for the Treatment of Subjects With Myelofibrosis Who Are Relapsed or Refractory to JAK Inhibitor Treatment

NCT04217993Phase 2CompletedPrimary

Jaktinib for the Treatment of Ruxolitinib Intolerance of Myelofibrosis

NCT03935555Phase 1TerminatedPrimary

Assess the Safety, Tolerability Oral PU-H71 in Subjects Taking Ruxolitinib

NCT04878003Phase 2UnknownPrimary

Study of KRT-232 or TL-895 in Janus Associated Kinase Inhibitor Treatment-Naïve Myelofibrosis

NCT00910728Phase 1CompletedPrimary

Study to Assess the Safety of AZD1480 in Patients With Myeloproliferative Diseases

NCT01558739Phase 4CompletedPrimary

Exploratory Phase II Study of INC424 Patients With Primary Myelofibrosis (PMF) or Post Polycythaemia Myelofibrosis (PPV MF) or Post Essential Thrombocythaemia Myelofibrosis (PET-MF)

Showing all 17 trials

Research Network

Activity Timeline