Key Insights

Highlights

Success Rate

100% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 40/100

Termination Rate

0.0%

0 terminated out of 23 trials

Success Rate

100.0%

+13.5% vs benchmark

Late-Stage Pipeline

13%

3 trials in Phase 3/4

Results Transparency

38%

6 of 16 completed with results

Key Signals

6 with results100% success

Data Visualizations

Phase Distribution

13Total
Not Applicable (1)
P 1 (2)
P 2 (7)
P 3 (3)

Trial Status

Completed16
Recruiting4
Unknown2
Withdrawn1

Trial Success Rate

100.0%

Benchmark: 86.5%

Based on 16 completed trials

Clinical Trials (23)

Showing 20 of 20 trials
NCT05001269Phase 2CompletedPrimary

Nedosiran in Pediatric Patients From Birth to 11 Years of Age With PH and Relatively Intact Renal Function

NCT05687474Completed

Baby Detect : Genomic Newborn Screening

NCT02026388RecruitingPrimary

Rare Kidney Stone Consortium Biobank

NCT04152200Phase 3Completed

A Study to Evaluate Lumasiran in Patients With Advanced Primary Hyperoxaluria Type 1

NCT00588562RecruitingPrimary

Rare Kidney Stone Consortium Patient Registry

NCT03905694Phase 3CompletedPrimary

A Study of Lumasiran in Infants and Young Children With Primary Hyperoxaluria Type 1

NCT03392896Phase 1CompletedPrimary

Study of DCR-PHXC-101 in Normal Healthy Volunteers and Patients With Primary Hyperoxaluria

NCT03350451Phase 2Completed

An Extension Study of an Investigational Drug, Lumasiran (ALN-GO1), in Participants With Primary Hyperoxaluria Type 1

NCT04125472UnknownPrimary

Expanded Access Protocol to Provide Lumasiran to Patients With Primary Hyperoxaluria Type 1

NCT06065852Recruiting

National Registry of Rare Kidney Diseases

NCT05843851Not ApplicableRecruiting

Genetic Newborn Screening for Cystinosis and Primary Hyperoxaluria

NCT02124395CompletedPrimary

Health-related Quality of Life in Rare Kidney Stone

NCT02000219Phase 2CompletedPrimary

Study to Evaluate the Efficacy and Safety of Oxabact (OC5) in Primary Hyperoxaluria Patients Who Are on Dialysis

NCT03116685Phase 3CompletedPrimary

A Study to Evaluate the Efficacy and Safety of Oxabact in Patients With Primary Hyperoxaluria

NCT05107830UnknownPrimary

Phenotyping of Primary Hyperoxaluria

NCT03819647Phase 2CompletedPrimary

Evaluation of the Efficacy of Stiripentol (Diacomit) as Monotherapy for the Treatment of Primary Hyperoxaluria

NCT03391804Phase 2Completed

Study of ALLN-177 in Patients Aged 12 Years or Older With Enteric or Primary Hyperoxaluria and Hyperoxalemia

NCT02340689CompletedPrimary

Primary Hyperoxaluria Mutation Genotyping/Phenotyping

NCT00589225CompletedPrimary

Primary Hyperoxaluria Mutation Genotyping

NCT02012985Phase 1CompletedPrimary

Study to Evaluate the Efficacy and Safety of Oxabact (OC5) in Patients With Primary Hyperoxaluria

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Research Network

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