Key Insights

Highlights

Success Rate

50% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 75/100

Termination Rate

7.1%

1 terminated out of 14 trials

Success Rate

50.0%

-36.5% vs benchmark

Late-Stage Pipeline

7%

1 trials in Phase 3/4

Results Transparency

0%

0 of 1 completed with results

Key Signals

50% success

Data Visualizations

Phase Distribution

13Total
Not Applicable (1)
P 1 (5)
P 2 (6)
P 4 (1)

Trial Status

Recruiting6
Active Not Recruiting3
Unknown2
Withdrawn1
Completed1
Terminated1

Trial Success Rate

50.0%

Benchmark: 86.5%

Based on 1 completed trials

Clinical Trials (14)

Showing 14 of 14 trials
NCT04627753Phase 2RecruitingPrimary

Study of Lenalidomide/Rituximab Maintenance for Transplantation Ineligible Patients With PCNSL.

NCT04947319Phase 2Active Not Recruiting

Study of Tirabrutinib (ONO-4059) in Patients With Primary Central Nervous System Lymphoma (PROSPECT Study)

NCT04134117Phase 1CompletedPrimary

Tisagenlecleucel In Primary CNS Lymphoma

NCT04464200Phase 1Active Not Recruiting

19(T2)28z1xx Chimeric Antigen Receptor (CAR) T Cells in People With B-Cell Cancers

NCT05036564Not ApplicableRecruitingPrimary

Diagnosis; Objective RespOnse; THErApy

NCT04443829Phase 1Active Not RecruitingPrimary

Immunotherapy Using CAR T-cells to Target CD19 for Relapsed/Refractory CD19+ Primary CNS Lymphoma

NCT04656431Phase 1RecruitingPrimary

Feasibility of Acquiring Hyperpolarized Imaging in Patients With Primary CNS Lymphoma

NCT04006561RecruitingPrimary

Prospective Neurobehavioral Functions in Newly-diagnosed Patients With Primary CNS Lymphoma Treated With Hyperfractionated Conformal Whole-brain Radiation Therapy Plus Simultaneous Integrated Boost

NCT05518383Phase 4Recruiting

B-cell Mature Non-Hodgkin's Lymphoma Treatment Protocol in Children and Adolescents 2021

NCT05425654Phase 2RecruitingPrimary

RL-MPV Followed by BBC HCT Using Autologous Stem Cells and Maintenance Therapy With Nivolumab for Newly Diagnosed PCNSL

NCT04073147Phase 1TerminatedPrimary

Venetoclax and Obinutuzumab for Relapsed/Refractory Primary CNS Lymphoma

NCT03569995Phase 2UnknownPrimary

[CREMA]Combination of R-M Followed by R-A in Elderly Patients With Primary CNS Lymphoma

NCT03212807Phase 2Withdrawn

Study Of Durvalumab and Lenalidomide In R/R EBV Associated DLBCL Subtypes, Primary CNS And Testicular DLBCL

NCT02934204Phase 2UnknownPrimary

Temozolomide in Treatment of Patients With Primary Central Nervous System Lymphoma

Showing all 14 trials

Research Network

Activity Timeline