Key Insights

Highlights

Success Rate

85% trial completion

Published Results

34 trials with published results (24%)

Research Maturity

73 completed trials (51% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 39/100

Termination Rate

9.0%

13 terminated out of 144 trials

Success Rate

84.9%

-1.7% vs benchmark

Late-Stage Pipeline

14%

20 trials in Phase 3/4

Results Transparency

47%

34 of 73 completed with results

Key Signals

34 with results85% success13 terminated

Data Visualizations

Phase Distribution

111Total
Not Applicable (12)
Early P 1 (2)
P 1 (31)
P 2 (46)
P 3 (17)
P 4 (3)

Trial Status

Completed73
Recruiting24
Terminated13
Active Not Recruiting11
Unknown10
Not Yet Recruiting7

Trial Success Rate

84.9%

Benchmark: 86.5%

Based on 73 completed trials

Clinical Trials (144)

Showing 20 of 20 trials
NCT06290765Phase 4WithdrawnPrimary

Efficacy and Safety of Ropeginterferon Alfa 2b (P1101) for Patients With Polycythemia Vera

NCT07648030Phase 2RecruitingPrimary

A Study of Rusfertide in Japanese Adults With Polycythemia Vera

NCT07734272Not ApplicableNot Yet RecruitingPrimary

Standardized Documentation and Assessments for Polycythemia Vera: A Quality Improvement Initiative

NCT07722611Phase 2Not Yet RecruitingPrimary

A Clinical Trial of Bomedemstat in Participants With Polycythemia Vera (MK-3543-025)

NCT03862157Phase 1Active Not Recruiting

Azacitidine, Venetoclax, and Pevonedistat in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

NCT07203768RecruitingPrimary

A ELN-Multicenter Study on Phenotypic Evolution and Clinical Outcomes

NCT06752941CompletedPrimary

LOW-PV Continuation

NCT06506084RecruitingPrimary

Observational Study on the Use of Ropeginterferon Alfa-2b in Polycythemia Vera (ROPEG-PV)

NCT07429266Phase 3RecruitingPrimary

INTREPID: A Study of Sapablursen Evaluating the Safety and Efficacy in Participants With Polycythemia Vera (PV)

NCT02386800Phase 4Active Not Recruiting

CINC424A2X01B Rollover Protocol

NCT03289910Phase 2Active Not Recruiting

Topotecan Hydrochloride and Carboplatin With or Without Veliparib in Treating Advanced Myeloproliferative Disorders and Acute Myeloid Leukemia or Chronic Myelomonocytic Leukemia

NCT05548062Active Not RecruitingPrimary

Study to Identify and Describe Predictive Factors for Thromboembolic Events in Patients With High-risk Polycythemia Vera

NCT06661915Phase 2Suspended

A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs)

NCT02493530Phase 1Completed

TGR-1202 + Ruxolitinib PMF PPV-MF PET-MF MDS/MPN Polycythemia Vera Resistant to Hydroxyurea

NCT05558696Phase 2CompletedPrimary

A Study of Bomedemstat (IMG-7289/MK-3543) in Participants With Polycythemia Vera (IMG-7289-CTP-203/MK-3543-004)

NCT05853458Phase 4TerminatedPrimary

Evaluation of HU-resistance in Adult Patients With Polycythemia Vera Who Meet PV-AIM Predictors

NCT04116502Phase 3RecruitingPrimary

MITHRIDATE: Ruxolitinib Versus Hydroxycarbamide or Interferon as First Line Therapy in High Risk Polycythemia Vera

NCT03878199Phase 1Terminated

Testing the Effect of Taking Ruxolitinib and CPX-351 in Combination for the Treatment of Advanced Phase Myeloproliferative Neoplasms

NCT01384513Phase 2Completed

A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies

NCT07518940Not ApplicableNot Yet Recruiting

ENERGIA: Personalized Exercise Program for Fatigue in Patients With Myeloproliferative Neoplasms and Chronic Myeloid Leukemia

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