Key Insights

Highlights

Success Rate

85% trial completion

Published Results

34 trials with published results (23%)

Research Maturity

74 completed trials (51% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 39/100

Termination Rate

8.9%

13 terminated out of 146 trials

Success Rate

85.1%

-1.5% vs benchmark

Late-Stage Pipeline

14%

20 trials in Phase 3/4

Results Transparency

46%

34 of 74 completed with results

Key Signals

34 with results85% success13 terminated

Data Visualizations

Phase Distribution

112Total
Not Applicable (12)
Early P 1 (2)
P 1 (31)
P 2 (47)
P 3 (17)
P 4 (3)

Trial Status

Completed74
Recruiting27
Terminated13
Active Not Recruiting11
Unknown10
Not Yet Recruiting6

Trial Success Rate

85.1%

Benchmark: 86.6%

Based on 74 completed trials

Clinical Trials (146)

Showing 20 of 20 trials
NCT07648030Phase 2RecruitingPrimary

A Study of Rusfertide in Japanese Adults With Polycythemia Vera

NCT06661915Phase 2Recruiting

A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs)

NCT07722611Phase 2RecruitingPrimary

A Clinical Trial of Bomedemstat in Participants With Polycythemia Vera (MK-3543-025)

NCT05548062Active Not RecruitingPrimary

Study to Identify and Describe Predictive Factors for Thromboembolic Events in Patients With High-risk Polycythemia Vera

NCT07839858CompletedPrimary

A Study of Real-world Use and Effectiveness of Cytoreductive Strategies for the Treatment of Second-line Polycythemia Vera in France

NCT04282187Phase 2Recruiting

Decitabine With Ruxolitinib, Fedratinib or Pacritinib for the Treatment of Accelerated/Blast Phase Myeloproliferative Neoplasms

NCT01831635CompletedPrimary

Myeloproliferative Neoplasms: an In-depth Case-control Study

NCT07429266Phase 3RecruitingPrimary

INTREPID: A Study of Sapablursen Evaluating the Safety and Efficacy in Participants With Polycythemia Vera (PV)

NCT07765602Phase 2Not Yet RecruitingPrimary

A Study of Rusfertide in Adults With Polycythemia Vera in China

NCT02386800Phase 4Active Not Recruiting

CINC424A2X01B Rollover Protocol

NCT07012109Phase 1RecruitingPrimary

Study of BEBT-507 Injection in Subjects With Polycythemia Vera (PV)

NCT05853458Phase 4TerminatedPrimary

Evaluation of HU-resistance in Adult Patients With Polycythemia Vera Who Meet PV-AIM Predictors

NCT06361641Not ApplicableRecruiting

Functional and Phenotypic Characterization of Monocytes in Myeloproliferative Syndromes

NCT06290765Phase 4WithdrawnPrimary

Efficacy and Safety of Ropeginterferon Alfa 2b (P1101) for Patients With Polycythemia Vera

NCT07734272Not ApplicableNot Yet RecruitingPrimary

Standardized Documentation and Assessments for Polycythemia Vera: A Quality Improvement Initiative

NCT03862157Phase 1Active Not Recruiting

Azacitidine, Venetoclax, and Pevonedistat in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

NCT06506084RecruitingPrimary

Observational Study on the Use of Ropeginterferon Alfa-2b in Polycythemia Vera (ROPEG-PV)

NCT07203768RecruitingPrimary

A ELN-Multicenter Study on Phenotypic Evolution and Clinical Outcomes

NCT06752941CompletedPrimary

LOW-PV Continuation

NCT03289910Phase 2Active Not Recruiting

Topotecan Hydrochloride and Carboplatin With or Without Veliparib in Treating Advanced Myeloproliferative Disorders and Acute Myeloid Leukemia or Chronic Myelomonocytic Leukemia

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Research Network

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