Key Insights

Highlights

Success Rate

80% trial completion

Published Results

11 trials with published results (11%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

9.3%

9 terminated out of 97 trials

Success Rate

80.0%

-6.5% vs benchmark

Late-Stage Pipeline

8%

8 trials in Phase 3/4

Results Transparency

31%

11 of 36 completed with results

Key Signals

11 with results80% success

Data Visualizations

Phase Distribution

53Total
Not Applicable (8)
Early P 1 (3)
P 1 (11)
P 2 (23)
P 3 (5)
P 4 (3)

Trial Status

Completed36
Recruiting24
Unknown15
Terminated9
Active Not Recruiting6
Withdrawn3

Trial Success Rate

80.0%

Benchmark: 86.5%

Based on 36 completed trials

Clinical Trials (97)

Showing 20 of 20 trials
NCT06607692Phase 1Recruiting

Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed).

NCT00004847Phase 1RecruitingPrimary

Diagnosis of Pheochromocytoma

NCT00107289Phase 2Recruiting

Iodine I 131 Metaiodobenzylguanidine in Treating Patients With Recurrent, Progressive, or Refractory Neuroblastoma or Malignant Pheochromocytoma or Paraganglioma

NCT05636618Phase 1Recruiting

Targeted Alpha-Particle Therapy for Advanced Somatostatin Receptor Type 2 (SSTR2) Positive Tumors

NCT03583528Active Not Recruiting

DOTATOC PET/CT for Imaging NET Patients

NCT00669266Recruiting

Adrenal Tumors - Pathogenesis and Therapy

NCT03541720Early Phase 1Active Not Recruiting

18F-Fluorodopamine PET Studies of Neuroblastoma and Pheochromocytoma

NCT03206060Phase 2RecruitingPrimary

Lu-177-DOTATATE (Lutathera) in Therapy of Inoperable Pheochromocytoma/ Paraganglioma

NCT04119024Phase 1Recruiting

Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors

NCT06427798Phase 1Recruiting

Somatostatin-Receptors (SSTR)-Agonist [212Pb]VMT-alpha-NET in Metastatic or Inoperable SSTR+ Gastrointestinal Neuroendocrine Tumor and Pheochromocytoma/Paraganglioma Previously Treated With Systemic Targeted Radioligand Therapy

NCT03946527Phase 2Active Not Recruiting

LAnreotide in Metastatic Pheochromocytoma / PARAganglioma (LAMPARA)

NCT03839498Phase 2Active Not RecruitingPrimary

Study of Axitinib (AG-013736) With Evaluation of the VEGF-pathway in Pheochromocytoma/Paraganglioma

NCT05636540Early Phase 1RecruitingPrimary

In Vivo PARP-1 Expression With 18F-FluorThanatrace PET/CT in Patients With Pheochromocytoma and Paraganglioma

NCT03165721Phase 2Terminated

A Phase II Trial of the DNA Methyl Transferase Inhibitor, Guadecitabine (SGI-110), in Children and Adults With Wild Type GIST,Pheochromocytoma and Paraganglioma Associated With Succinate Dehydrogenase Deficiency and HLRCC-associated Kidney Cancer

NCT04711135Phase 2Active Not Recruiting

Study to Evaluate Safety and Dosimetry of Lutathera in Adolescent Patients With GEP-NETs and PPGLs

NCT01022515Not ApplicableCompletedPrimary

Specificity of Elevated Plasma EM66 Levels in Pheochromocytoma

NCT04187404Phase 1Terminated

A Novel Therapeutic Vaccine (EO2401) in Metastatic Adrenocortical Carcinoma, or Malignant Pheochromocytoma/Paraganglioma

NCT06573723Recruiting

Institutional Registry of Rare Diseases

NCT03160274RecruitingPrimary

Genetic Analysis of Pheochromocytomas, Paragangliomas and Associated Conditions

NCT07200245Not Yet RecruitingPrimary

Cardiovascular Complications After Adrenalectomy for Pheochromocytoma and Non-secreting Tumors

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