Key Insights

Highlights

Success Rate

80% trial completion

Published Results

11 trials with published results (11%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

9.0%

9 terminated out of 100 trials

Success Rate

80.4%

-6.1% vs benchmark

Late-Stage Pipeline

8%

8 trials in Phase 3/4

Results Transparency

30%

11 of 37 completed with results

Key Signals

11 with results80% success

Data Visualizations

Phase Distribution

56Total
Not Applicable (8)
Early P 1 (3)
P 1 (12)
P 2 (25)
P 3 (5)
P 4 (3)

Trial Status

Completed37
Recruiting25
Unknown14
Terminated9
Active Not Recruiting6
Not Yet Recruiting5

Trial Success Rate

80.4%

Benchmark: 86.6%

Based on 37 completed trials

Clinical Trials (100)

Showing 20 of 20 trials
NCT03015844Unknown

A Compassionate Use/Expanded Access Protocol Using 131I-MIBG Therapy for Patients With Refractory Neuroblastoma and Metastatic Pheochromocytoma

NCT00004847Phase 1RecruitingPrimary

Diagnosis of Pheochromocytoma

NCT07714551Phase 2Not Yet RecruitingPrimary

Zanzalintinib in Unresectable and Progressive MPGGs

NCT04573816CompletedPrimary

Development of a Tele-monitoring Program for Patients Undergoing Surgery for Pheochromocytoma and / or Paraganglioma

NCT06427798Phase 1Recruiting

Somatostatin-Receptors (SSTR)-Agonist [212Pb]VMT-alpha-NET in Metastatic or Inoperable SSTR+ Gastrointestinal Neuroendocrine Tumor and Pheochromocytoma/Paraganglioma Previously Treated With Systemic Targeted Radioligand Therapy

NCT07680205Phase 2Recruiting

An Experimental Study of Belzutifan Impact on Catecholamine Metabolism

NCT07661420Phase 1Not Yet RecruitingPrimary

211At-MABG in Adults With Advanced Neuroendocrine Cancers

NCT03541720Early Phase 1Active Not Recruiting

18F-Fluorodopamine PET Studies of Neuroblastoma and Pheochromocytoma

NCT06607692Phase 1Recruiting

Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed).

NCT00107289Phase 2Recruiting

Iodine I 131 Metaiodobenzylguanidine in Treating Patients With Recurrent, Progressive, or Refractory Neuroblastoma or Malignant Pheochromocytoma or Paraganglioma

NCT05636618Phase 1Recruiting

Targeted Alpha-Particle Therapy for Advanced Somatostatin Receptor Type 2 (SSTR2) Positive Tumors

NCT03583528Active Not Recruiting

DOTATOC PET/CT for Imaging NET Patients

NCT00669266Recruiting

Adrenal Tumors - Pathogenesis and Therapy

NCT03206060Phase 2RecruitingPrimary

Lu-177-DOTATATE (Lutathera) in Therapy of Inoperable Pheochromocytoma/ Paraganglioma

NCT04119024Phase 1Recruiting

Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors

NCT03839498Phase 2Active Not RecruitingPrimary

Study of Axitinib (AG-013736) With Evaluation of the VEGF-pathway in Pheochromocytoma/Paraganglioma

NCT03946527Phase 2Active Not Recruiting

LAnreotide in Metastatic Pheochromocytoma / PARAganglioma (LAMPARA)

NCT05636540Early Phase 1RecruitingPrimary

In Vivo PARP-1 Expression With 18F-FluorThanatrace PET/CT in Patients With Pheochromocytoma and Paraganglioma

NCT03165721Phase 2Terminated

A Phase II Trial of the DNA Methyl Transferase Inhibitor, Guadecitabine (SGI-110), in Children and Adults With Wild Type GIST,Pheochromocytoma and Paraganglioma Associated With Succinate Dehydrogenase Deficiency and HLRCC-associated Kidney Cancer

NCT04711135Phase 2Active Not Recruiting

Study to Evaluate Safety and Dosimetry of Lutathera in Adolescent Patients With GEP-NETs and PPGLs

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