Key Insights

Highlights

Success Rate

80% trial completion

Published Results

11 trials with published results (11%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

9.3%

9 terminated out of 97 trials

Success Rate

80.0%

-6.5% vs benchmark

Late-Stage Pipeline

8%

8 trials in Phase 3/4

Results Transparency

31%

11 of 36 completed with results

Key Signals

11 with results80% success

Data Visualizations

Phase Distribution

53Total
Not Applicable (8)
Early P 1 (3)
P 1 (11)
P 2 (23)
P 3 (5)
P 4 (3)

Trial Status

Completed36
Recruiting24
Unknown15
Terminated9
Active Not Recruiting6
Withdrawn3

Trial Success Rate

80.0%

Benchmark: 86.5%

Based on 36 completed trials

Clinical Trials (97)

Showing 20 of 20 trials
NCT06607692Phase 1Recruiting

Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed).

NCT00107289Phase 2Recruiting

Iodine I 131 Metaiodobenzylguanidine in Treating Patients With Recurrent, Progressive, or Refractory Neuroblastoma or Malignant Pheochromocytoma or Paraganglioma

NCT03206060Phase 2RecruitingPrimary

Lu-177-DOTATATE (Lutathera) in Therapy of Inoperable Pheochromocytoma/ Paraganglioma

NCT00004847Phase 1RecruitingPrimary

Diagnosis of Pheochromocytoma

NCT04119024Phase 1Recruiting

Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors

NCT06427798Phase 1Recruiting

Somatostatin-Receptors (SSTR)-Agonist [212Pb]VMT-alpha-NET in Metastatic or Inoperable SSTR+ Gastrointestinal Neuroendocrine Tumor and Pheochromocytoma/Paraganglioma Previously Treated With Systemic Targeted Radioligand Therapy

NCT03946527Phase 2Active Not Recruiting

LAnreotide in Metastatic Pheochromocytoma / PARAganglioma (LAMPARA)

NCT03839498Phase 2Active Not RecruitingPrimary

Study of Axitinib (AG-013736) With Evaluation of the VEGF-pathway in Pheochromocytoma/Paraganglioma

NCT05636540Early Phase 1RecruitingPrimary

In Vivo PARP-1 Expression With 18F-FluorThanatrace PET/CT in Patients With Pheochromocytoma and Paraganglioma

NCT03165721Phase 2Terminated

A Phase II Trial of the DNA Methyl Transferase Inhibitor, Guadecitabine (SGI-110), in Children and Adults With Wild Type GIST,Pheochromocytoma and Paraganglioma Associated With Succinate Dehydrogenase Deficiency and HLRCC-associated Kidney Cancer

NCT04711135Phase 2Active Not Recruiting

Study to Evaluate Safety and Dosimetry of Lutathera in Adolescent Patients With GEP-NETs and PPGLs

NCT01022515Not ApplicableCompletedPrimary

Specificity of Elevated Plasma EM66 Levels in Pheochromocytoma

NCT04187404Phase 1Terminated

A Novel Therapeutic Vaccine (EO2401) in Metastatic Adrenocortical Carcinoma, or Malignant Pheochromocytoma/Paraganglioma

NCT06573723Recruiting

Institutional Registry of Rare Diseases

NCT03541720Early Phase 1Active Not Recruiting

18F-Fluorodopamine PET Studies of Neuroblastoma and Pheochromocytoma

NCT05636618Phase 1Recruiting

Targeted Alpha-Particle Therapy for Advanced Somatostatin Receptor Type 2 (SSTR2) Positive Neuroendocrine Tumors

NCT03160274RecruitingPrimary

Genetic Analysis of Pheochromocytomas, Paragangliomas and Associated Conditions

NCT07200245Not Yet RecruitingPrimary

Cardiovascular Complications After Adrenalectomy for Pheochromocytoma and Non-secreting Tumors

NCT07195500Recruiting

Clinical Application of Somatostatin Receptor and Norepinephrine Transporter Targeted Imaging for Diagnosis and Staging of Neuroblastoma and Pheochromocytoma/Paraganglioma

NCT00669266Recruiting

Adrenal Tumors - Pathogenesis and Therapy

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