Pharmacodynamics
53
3
3
38
Key Insights
Highlights
Success Rate
97% trial completion (above average)
Published Results
13 trials with published results (25%)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 40/100
1.9%
1 terminated out of 53 trials
97.4%
+10.9% vs benchmark
11%
6 trials in Phase 3/4
34%
13 of 38 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 38 completed trials
Clinical Trials (53)
Comparison of the Pharmacokinetics (PK) and Pharmacodynamics (PD) Biosimilarity of Proposed Biosimilar/Interchangeable Rapid-Acting Insulin Aspart (I004) and NovoLog® After Single-Dose Subcutaneous Administration to Healthy Volunteers
Comparison of the Pharmacokinetics (PK) and Pharmacodynamics (PD) Biosimilarity of Proposed Biosimilar Rapid-Acting Insulin Aspart (I004) and NovoLog After Single-Dose Subcutaneous Administration to Healthy Volunteers
Study of BB-025, Alone and After BB-031, in Healthy Volunteers
Reevaluation Prediction of the Effect Site Propofol Eleveld Model Using Slow and Fast Induction
Single Ascending Doses of Kratom in Healthy Nondependent Adults With Opioid Experience
Safety, Tolerability & Potential Anti-cancer Activity of Increasing Doses of AZD5363 in Different Treatment Schedules
Effect of Oral Water in Healthy Volunteers on Cardiac Output, Regional Flow and Microcirculation in Healthy Volunteers
Clinical Decision Support Tool for Vancomycin Dosing in Children
Single Ascending Dose and Multiple Ascending Dose Study of AVR-48
Study to Evaluate Pharmacokinetic and Pharmacodynamic Drug Interactions and Safety of IY-NS250 and IY-NT-SR
KF2023#1-Trial: Influence of Statin Intake on Cellular Readouts
Pharmacodynamic Biomarkers to Support Biosimilar Development: PCSK9 Inhibitors
Pharmacodynamic Biomarkers to Support Biosimilar Development: Interleukin-5 Antagonists
Pharmacodynamic Biomarkers to Support Biosimilar Development: Interferon Beta-1A Products
SB17170 Phase1 Trial in Healthy Volunteer
Electrophysiological Effects of Potential QT Prolonging Drugs
Imapct of bioMarkers on Pharmacodynamics and Bleeding Risk of Direct Oral AntiCoagulants and Ticagrelor Study II
Double-blind, Randomized Comparative Cross-sectional Study of Pharmacodynamics and Pharmacokinetics of Drugs GP40141
Modeling and Application of Triple Drug Response Surface Models
Study of DTRI-031 in Healthy Volunteers