Key Insights

Highlights

Success Rate

70% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 47/100

Termination Rate

18.8%

3 terminated out of 16 trials

Success Rate

70.0%

-16.5% vs benchmark

Late-Stage Pipeline

6%

1 trials in Phase 3/4

Results Transparency

71%

5 of 7 completed with results

Key Signals

5 with results70% success

Data Visualizations

Phase Distribution

12Total
Not Applicable (5)
P 1 (2)
P 2 (4)
P 3 (1)

Trial Status

Completed7
Terminated3
Unknown2
Recruiting1
Withdrawn1
Not Yet Recruiting1

Trial Success Rate

70.0%

Benchmark: 86.5%

Based on 7 completed trials

Clinical Trials (16)

Showing 16 of 16 trials
NCT04938167Not ApplicableActive Not RecruitingPrimary

Preductal Oxygen Saturation Target in Term and Late Preterm Neonates With Hypoxemic Respiratory Failure or Pulmonary Hypertension

NCT00710177RecruitingPrimary

PTGS1 Genetic Variation and Increased Risk for Persistent Pulmonary Hypertension of the Newborn

NCT02951130Phase 2Completed

Milrinone in Congenital Diaphragmatic Hernia

NCT05741229Not ApplicableCompletedPrimary

The Effect Of Nebulizied Nitroglycerin As An Adjuvant Therapy For Persistent Pulmonary Hypertension Of Newborns

NCT06832163Not ApplicableNot Yet RecruitingPrimary

Close Loop Smart Weaning for INO With PPHN

NCT01389856Phase 3TerminatedPrimary

Persistent Pulmonary Hypertension of the Newborn

NCT06562036Not ApplicableCompletedPrimary

Efficacy of Milrinone With Sildenafil in Persistent Pulmonary Hypertension in Children

NCT02261883Phase 2TerminatedPrimary

Remodulin as Add-on Therapy for the Treatment of Persistent Pulmonary Hypertension of the Newborn

NCT04841070Not ApplicableCompletedPrimary

NEURodevelopmental Outcome After Persistent Pulmonary Hypertension Of the Newborn

NCT01360671Phase 2WithdrawnPrimary

IV Sildenafil Persistent Pulmonary Hypertension Of The Newborn

NCT01069861Phase 2Terminated

Study To Investigate Safety And Efficacy Of Sildenafil In The Newborns With Persistent Pulmonary Hypertension (PPHN)

NCT04328636Phase 1Completed

Nebulized MgSO4 in Persistent Pulmonary Hypertension of Newborn

NCT04379180UnknownPrimary

Population Pharmacokinetics and Dosage Individualization of Oral Pulmonary Vasodilators in PPHN

NCT02940327CompletedPrimary

Markers of Inflammation and Lung Recovery in ECMO Patients for PPHN

NCT01670136Phase 1CompletedPrimary

Pharmacokinetics of Sildenafil in Premature Infants

NCT02380040Unknown

Plethismographic Perfusion Index in Neonates

Showing all 16 trials

Research Network

Activity Timeline