Persistent Fetal Circulation Syndrome
9
0
0
4
Key Insights
Highlights
Success Rate
57% trial completion
Treatment Research
5 treatments under study, led by Nitric Oxide
Research Leaders
15 sponsors active, led by NICHD Neonatal Research Network
Related Conditions
Often studied with 17 related conditions
Clinical Risk Assessment
Based on trial outcomes
High Risk
Score: 80/100
33.3%
3 terminated out of 9 trials
57.1%
-29.5% vs benchmark
44%
4 trials in Phase 3/4
25%
1 of 4 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.6%
Based on 4 completed trials
Clinical Trials (9)
Antibody Secreting Cell and Cyotokine Profiles in Neonates on ECMO
Early iNO for Oxidative Stress, Vascular Tone and Inflammation in Babies With Hypoxic Respiratory Failure
Persistent Pulmonary Hypertension of the Newborn (PPHN) Observational Study
Early Inhaled Nitric Oxide for Respiratory Failure in Newborns
Inhaled Nitric Oxide Study for Respiratory Failure in Newborns
Pharmacokinetic Study of Milrinone in Babies With Persistent Pulmonary Hypertension of the Newborn
Risk Factors for Pulmonary Hypertension of the Newborn
Epidemiology of Persistent Pulmonary Hypertension of the Newborn - SCOR in Lung Biology and Diseases in Infants and Children
Sildenofil in Persistent Pulmonary Hypertension in Newborns
Research Network
Common Treatments
- Nitric Oxide3
- Diluent1
- Milrinone Lactate1
- Sildenafil1
- Standard Ino Therapy1
Active Sponsors
- NICHD Neonatal Research Network3
- National Center for Research Resources (NCRR)3
- National Heart, Lung, and Blood Institute (NHLBI)2
- Mallinckrodt2
- The University of Texas Health Science Center, Houston1
Top Investigators
University of New Mexico
Children's Hospital Medical Center, Cincinnati
Yale University
Baylor College of Medicine
University of Miami
Related Conditions
- Infant Newborn3
- Respiratory Insufficiency2
- Pneumonia Aspiration2
- Hypertension Pulmonary2
- Respiratory Distress Syndrome Newborn2