Key Insights

Highlights

Success Rate

80% trial completion

Published Results

49 trials with published results (36%)

Research Maturity

79 completed trials (57% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

14.5%

20 terminated out of 138 trials

Success Rate

79.8%

-6.7% vs benchmark

Late-Stage Pipeline

7%

10 trials in Phase 3/4

Results Transparency

62%

49 of 79 completed with results

Key Signals

49 with results80% success20 terminated

Data Visualizations

Phase Distribution

129Total
Not Applicable (8)
Early P 1 (1)
P 1 (58)
P 2 (52)
P 3 (8)
P 4 (2)

Trial Status

Completed79
Terminated20
Recruiting16
Unknown15
Withdrawn3
Not Yet Recruiting2

Trial Success Rate

79.8%

Benchmark: 86.5%

Based on 79 completed trials

Clinical Trials (138)

Showing 20 of 20 trials
NCT06362148Active Not RecruitingPrimary

Circulating Tumor DNA in Peripheral T-cell Lymphomas

NCT07523555Phase 1Recruiting

Adaptive Dual-Target CAR-T Cells for Relapsed or Refractory Hematologic Malignancies

NCT06176690Phase 1Recruiting

Constitutive IL7R (C7R) Modified Banked Allogeneic CD30.CAR EBVSTS for CD30-Positive Lymphomas

NCT04512534Phase 2RecruitingPrimary

Sintilimab Combined With Chidamide in Treating Peripheral T Cell Lymphoma

NCT01846390Phase 1CompletedPrimary

Romidepsin, Gemcitabine, Dexamethasone and Cisplatin in the Treatment of Peripheral T-Cell and Diffuse Large B-Cell Lymphoma

NCT07270861RecruitingPrimary

Real-world Outcomes of Peripheral T-cell Lymphoma: A Multicenter Retrospective and Prospective Cohort Study

NCT07215832Unknown

Karyopharm Expanded Access Program for Selinexor

NCT07055477Phase 1Recruiting

A Phase I Trial Anti-CC Chemokine Receptor 4 Chimeric Antigen Receptor T Cells (CCR4 CAR T Cells) for CCR4 Expressing T-cell Malignancies Including Peripheral T-cell Non-Hodgkin Lymphoma (PTCL) and Cutaneous T-cell Non-Hodgkin Lymphoma (CTCL)

NCT04569032Phase 2CompletedPrimary

A Study of Brentuximab Vedotin and CHP in Frontline Treatment of PTCL With Less Than 10% CD30 Expression

NCT02362997Phase 2Completed

Pembrolizumab After ASCT for Hodgkin Lymphoma, DLBCL and T-NHL

NCT04447027Phase 1Completed

Romidepsin, CC-486 (5-azacitidine), Dexamethasone, and Lenalidomide (RAdR) for Relapsed/Refractory T-cell Malignancies

NCT02264613Phase 1Completed

ALRN-6924 in Patients With Advanced Solid Tumors or Lymphomas

NCT04425070Phase 1TerminatedPrimary

A Study of Evaluating the Safety and Efficacy of ATG-010 Combined With Chemotherapy Sequential With ATG-010 Monotherapy Maintenance in Peripheral T- and NK/T-cell Lymphoma

NCT07283822Phase 2Recruiting

Amping up With PemJAK

NCT06421948Phase 1RecruitingPrimary

Linperlisib Combined With Chidamide in Patients With PTCL

NCT07258680Phase 3Enrolling By InvitationPrimary

BrEto-TCL - Defining the Role of Brentuximab and Etoposide for Optimizing First-line Therapy of T-cell Lymphomas

NCT05083208Phase 1TerminatedPrimary

PI3Kδ Inhibitor Parsaclisib Combined With Chidamide for the Treatment of Relapsed/Refractory Peripheral T-cell Lymphoma

NCT07234162Phase 3RecruitingPrimary

A Phase 3 Multinational Study of Golidocitinib Versus Investigator's Choice in r/r PTCL (JACKPOT19)

NCT04234048Phase 1Recruiting

Phase 1 Trial of ST-001 nanoFenretinide in Relapsed/Refractory T-cell Non-Hodgkin Lymphoma

NCT02512497Phase 1Completed

Romidepsin Maintenance After Allogeneic Stem Cell Transplantation

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