Key Insights

Highlights

No notable highlights available yet

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 65/100

Termination Rate

4.0%

1 terminated out of 25 trials

Success Rate

0.0%

-86.5% vs benchmark

Late-Stage Pipeline

20%

5 trials in Phase 3/4

Results Transparency

0%

0 of 0 completed with results

Key Signals

0

Data Visualizations

Phase Distribution

20Total
Not Applicable (2)
Early P 1 (1)
P 1 (11)
P 2 (1)
P 3 (5)

Trial Status

Recruiting14
Active Not Recruiting3
Not Yet Recruiting3
Unknown3
Terminated1
Withdrawn1

Clinical Trials (25)

Showing 20 of 20 trials
NCT07252232Phase 3Recruiting

Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)

NCT07573215UnknownPrimary

Expanded Access Program for Daraxonrasib (RMC-6236) in Previously Treated Metastatic Pancreatic Adenocarcinoma

NCT07562152Phase 3Recruiting

Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma

NCT06445062Phase 1Recruiting

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

NCT07490301Phase 2Recruiting

A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination With Fluorouracil, Folinic Acid, and Oxaliplatin (FOLFOX) Compared to Standard of Care in Adult Participants With First-Line Metastatic Pancreatic Ductal Adenocarcinoma

NCT07491445Phase 3Recruiting

Study of Daraxonrasib and Daraxonrasib + GnP as First-line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma

NCT07349537Phase 1Recruiting

Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors

NCT05355298Phase 1Active Not Recruiting

ACCENT: AMP945 in Combination With Nab-paclitaxel and Gemcitabine for Treatment of Pancreatic Cancer

NCT07621718Phase 3Recruiting

Study of Zoldonrasib + Chemo of Investigator's Choice vs Placebo + Chemo of Investigator's Choice as First-line Treatment in Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma ( RASolute 305 )

NCT07145450Phase 1RecruitingPrimary

Master Protocol of TCR-modified T Cell Therapy Targeting HLA-restricted KRAS Antigen Administered in Adult Patients With Metastatic or Locally Advanced PDAC

NCT06625320Phase 3Active Not Recruiting

Phase 3 Study of Daraxonrasib (RMC-6236) in Patients With Previously Treated Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)

NCT06122896Early Phase 1Recruiting

Prospective Screening for Pancreatic Ductal Adenocarcinoma in High-Risk Individuals

NCT07605702Not Yet Recruiting

The Canopy Cancer Collective Clinical Registry Protocol

NCT06922591Phase 1RecruitingPrimary

Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients

NCT06151223Recruiting

A Prospective Registry for Patients at High-Risk for Pancreatic Cancer

NCT07441174Phase 1Recruiting

IN10018 in Combination With RNK08954 for the Treatment of KRASG12D Mutation-Positive Locally Advanced or Metastatic Solid Tumors

NCT05642962Phase 1Active Not Recruiting

Pancrelipase in People With Pancreatic Ductal Adenocarcinoma (PDAC)

NCT07259590Phase 1Recruiting

A Study of GFH375 Combined With Cetuximab or Chemotherapy in Participants With Solid Tumors Harboring KRAS G12D Mutation

NCT07198321Phase 1Not Yet Recruiting

A Single-Arm, Open-Label, Multicenter Phase I/II Clinical Study of GFH276 in Patients With RAS-Mutant Advanced Solid Tumors

NCT06592664Phase 1Withdrawn

Certepetide Phase 1b/2a Continuous Infusion Trial in mPDAC

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