Key Insights

Highlights

Success Rate

65% trial completion

Published Results

13 trials with published results (20%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 47/100

Termination Rate

10.9%

7 terminated out of 64 trials

Success Rate

65.0%

-21.5% vs benchmark

Late-Stage Pipeline

6%

4 trials in Phase 3/4

Results Transparency

100%

13 of 13 completed with results

Key Signals

13 with results65% success

Data Visualizations

Phase Distribution

40Total
Not Applicable (5)
Early P 1 (2)
P 1 (10)
P 2 (19)
P 3 (2)
P 4 (2)

Trial Status

Recruiting17
Unknown15
Completed13
Active Not Recruiting7
Terminated7
Withdrawn4

Trial Success Rate

65.0%

Benchmark: 86.5%

Based on 13 completed trials

Clinical Trials (64)

Showing 20 of 20 trials
NCT02834013Phase 2Active Not Recruiting

Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

NCT05636618Phase 1Recruiting

Targeted Alpha-Particle Therapy for Advanced Somatostatin Receptor Type 2 (SSTR2) Positive Tumors

NCT03206060Phase 2Recruiting

Lu-177-DOTATATE (Lutathera) in Therapy of Inoperable Pheochromocytoma/ Paraganglioma

NCT06607692Phase 1Recruiting

Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed).

NCT04119024Phase 1Recruiting

Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors

NCT03946527Phase 2Active Not RecruitingPrimary

LAnreotide in Metastatic Pheochromocytoma / PARAganglioma (LAMPARA)

NCT03839498Phase 2Active Not Recruiting

Study of Axitinib (AG-013736) With Evaluation of the VEGF-pathway in Pheochromocytoma/Paraganglioma

NCT05636540Early Phase 1Recruiting

In Vivo PARP-1 Expression With 18F-FluorThanatrace PET/CT in Patients With Pheochromocytoma and Paraganglioma

NCT03165721Phase 2TerminatedPrimary

A Phase II Trial of the DNA Methyl Transferase Inhibitor, Guadecitabine (SGI-110), in Children and Adults With Wild Type GIST,Pheochromocytoma and Paraganglioma Associated With Succinate Dehydrogenase Deficiency and HLRCC-associated Kidney Cancer

NCT04711135Phase 2Active Not Recruiting

Study to Evaluate Safety and Dosimetry of Lutathera in Adolescent Patients With GEP-NETs and PPGLs

NCT01022515Not ApplicableCompleted

Specificity of Elevated Plasma EM66 Levels in Pheochromocytoma

NCT04187404Phase 1Terminated

A Novel Therapeutic Vaccine (EO2401) in Metastatic Adrenocortical Carcinoma, or Malignant Pheochromocytoma/Paraganglioma

NCT06573723Recruiting

Institutional Registry of Rare Diseases

NCT04081701Phase 4Recruiting

68-Ga DOTATATE PET/MRI in the Diagnosis and Management of Somatostatin Receptor Positive CNS Tumors.

NCT05142241Phase 2Active Not Recruiting

Testing the Combination of Anti-Cancer Drugs Talazoparib and Temozolomide in Patients With Advanced Stage Rare Cancers, RARE 2 Trial

NCT03160274Recruiting

Genetic Analysis of Pheochromocytomas, Paragangliomas and Associated Conditions

NCT07195500Recruiting

Clinical Application of Somatostatin Receptor and Norepinephrine Transporter Targeted Imaging for Diagnosis and Staging of Neuroblastoma and Pheochromocytoma/Paraganglioma

NCT06377033Not ApplicableRecruiting

Using the EHR to Advance Genomic Medicine Across a Diverse Health System

NCT05233878Active Not RecruitingPrimary

Prognostic's Factors of Head and Neck Paragangliomas Evolution

NCT04400474Phase 2Completed

Trial of Cabozantinib Plus Atezolizumab in Advanced and Progressive Neoplasms of the Endocrine System. The CABATEN Study

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