Key Insights

Highlights

Success Rate

58% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 75/100

Termination Rate

31.3%

5 terminated out of 16 trials

Success Rate

58.3%

-28.2% vs benchmark

Late-Stage Pipeline

6%

1 trials in Phase 3/4

Results Transparency

71%

5 of 7 completed with results

Key Signals

5 with results58% success

Data Visualizations

Phase Distribution

12Total
Not Applicable (2)
P 1 (4)
P 2 (5)
P 3 (1)

Trial Status

Completed7
Terminated5
Unknown2
Recruiting1
Active Not Recruiting1

Trial Success Rate

58.3%

Benchmark: 86.5%

Based on 7 completed trials

Clinical Trials (16)

Showing 16 of 16 trials
NCT03333200Recruiting

Longitudinal Study of Neurodegenerative Disorders

NCT01019876Phase 2Completed

Risk-Adapted Allogeneic Stem Cell Transplantation For Mixed Donor Chimerism In Patients With Non-Malignant Diseases

NCT02666768Phase 2CompletedPrimary

ACTIMMUNE in Intermediate Osteopetrosis

NCT06521580Not ApplicableCompletedPrimary

Outcomes of Patients With Osteopetrosis Weight-bearing Bone Fractures

NCT02065869Phase 1Terminated

Safety Study of Gene Modified Donor T-cells Following TCRαβ+ Depleted Stem Cell Transplant

NCT03301168Phase 1Active Not Recruiting

Study of Gene Modified Donor T-cells Following TCR Alpha Beta Positive Depleted Stem Cell Transplant

NCT00968864Phase 2Terminated

T-cell Depleted Alternative Donor Transplantation

NCT01200017Unknown

Expanded Access Protocol (EAP) Using the CliniMACS® Device for Pediatric Haplocompatible Donor Stem Cell Transplant

NCT00638820Phase 2TerminatedPrimary

Reduced Intensity AlloTransplant For Osteopetrosis

NCT00145587Not ApplicableTerminatedPrimary

Stem Cell Transplantation for Children Affected With Osteopetrosis

NCT00730314Phase 1Completed

Unrelated Hematopoietic Stem Cell Transplantation(HSCT) for Genetic Diseases of Blood Cells

NCT00145886Phase 1TerminatedPrimary

rhPTH Therapy for Low Turnover Bone Fragility

NCT00004402Phase 3CompletedPrimary

Phase III Randomized Study of Interferon Gamma in Children With Severe, Congenital Osteopetrosis

NCT01087398Phase 2UnknownPrimary

Hematopoietic Stem Cell Transplantation for Malignant Infantile Osteopetrosis

NCT01199094CompletedPrimary

Clinical Assessment of Patients With High Bone Mass Due to Mutation in Lrp5

NCT00043329CompletedPrimary

Post Marketing Surveillance Study of Actimmune in Patients With Severe, Malignant Osteopetrosis

Showing all 16 trials

Research Network

Activity Timeline