Osteogenesis Imperfecta
72
9
18
39
Key Insights
Highlights
Success Rate
89% trial completion (above average)
Published Results
12 trials with published results (17%)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 40/100
6.9%
5 terminated out of 72 trials
88.6%
+2.1% vs benchmark
21%
15 trials in Phase 3/4
31%
12 of 39 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 39 completed trials
Clinical Trials (72)
Study to Evaluate Efficacy and Safety of Romosozumab Compared With Bisphosphonates in Children and Adolescents With Osteogenesis Imperfecta
Effects of Bisphosphonates on OI-Related Hearing Loss
Evaluation and Intervention for the Effects of Osteogenesis Imperfecta
Pediatric Safety Follow-up Study of Prior Treatment With Romosozumab for Osteogenesis Imperfecta
Evaluation and Treatment of Patients With Connective Tissue Disease
Setrusumab in Pediatric Japanese Subjects With Osteogenesis Imperfecta
Cardiopulmonary Outcomes in Osteogenesis Imperfecta: BBD7708
Setrusumab vs Bisphosphonates in Pediatric Subjects With Osteogenesis Imperfecta
Setrusumab vs Placebo for Osteogenesis Imperfecta
Natural History of the Collagen-Related Disorder Osteogenesis Imperfecta and Genotype Phenotype Correlation
REMS25: Study on the Use of REMS Technology in Diseases Commonly Associated With Reduced Bone Mineral Density (BMD)
Dental Malocclusion and Craniofacial Development in OI
Post-market Observational Study on JTIN Telescopic Nail in Osteogenesis Imperfecta Pediatric Patients
Prospective Observational Cohort Study of Cardiac Structure and Function in Children and Adults With Osteogenesis Imperfecta
Clear Aligners for the Treatment of Dental Malocclusion in OI
Urinary Biomarkers of OI Pathobiology
Registry of Osteogenesis Imperfecta
Mesenchymal Cell Therapy in Osteogenesis Imperfecta (OI)
Treatment of Osteogenesis Imperfecta With Parathyroid Hormone and Zoledronic Acid
Pediatric Arthropathy Beyond Inflammation: Clinical Spectrum and Diagnostic Approach at Assiut University Children Hospital