Key Insights

Highlights

Success Rate

73% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

12.1%

4 terminated out of 33 trials

Success Rate

73.3%

-13.2% vs benchmark

Late-Stage Pipeline

6%

2 trials in Phase 3/4

Results Transparency

45%

5 of 11 completed with results

Key Signals

5 with results73% success

Data Visualizations

Phase Distribution

18Total
Not Applicable (3)
P 1 (3)
P 2 (10)
P 3 (1)
P 4 (1)

Trial Status

Completed11
Recruiting7
Terminated4
Unknown4
Not Yet Recruiting4
Active Not Recruiting2

Trial Success Rate

73.3%

Benchmark: 86.5%

Based on 11 completed trials

Clinical Trials (33)

Showing 20 of 20 trials
NCT05237960Phase 2Active Not Recruiting

Metformin for the Prevention of Oral Cancer in Patients With Oral Leukoplakia or Erythroplakia

NCT02581137Phase 2Active Not Recruiting

Metformin Hydrochloride in Preventing Oral Cancer in Patients With an Oral Premalignant Lesion

NCT06876038Phase 2Not Yet Recruiting

Low-cost Screening and Image-guided Photodynamic Therapy (PDT) of Premalignant and Malignant Oral Lesions

NCT07453472Phase 3Not Yet RecruitingPrimary

Comparison of Topical Photodynamic Therapy With Topical Calcipotriol in Management of Oral Leukoplakia

NCT07416318Completed

Unveiling the Protein Expression Patterns in Oral Lichen Planus and Leukoplakia Through Comparative Salivary Proteomics

NCT07387900Phase 2RecruitingPrimary

Evaluation of the Chemo-preventive Effect of Combined Topical and Systemic Metformin on Oral Leukoplakia

NCT07331935Not ApplicableRecruitingPrimary

Efficacy of Topical Coenzyme Q10 and Curcumin for Oral Leukoplakia Treatment

NCT07318922Not Yet Recruiting

Evaluation of Artificial Intelligence in Diagnosis and Risk Assessment of Oral Potentially Malignant Disorders

NCT05727761Phase 2RecruitingPrimary

Pioglitazone-Metformin Combination Treatment for High Risk Oral Preneoplasia

NCT07149220Phase 1RecruitingPrimary

Fenretinide Mucoadhesive Patch: Evaluation of Oral Cancer Prevention Efficacy in Adults With Premalignant Oral Lesions.

NCT00341497Completed

Biomarkers for Oral Cancer

NCT06321003Recruiting

SYsteMatical Trained learnIng aLgorithms for Oral carcInogenesiS Interpretation by Optical Coherence Tomography

NCT06469892CompletedPrimary

Saliva and Plasma Exosomes for Oral Leukoplakia Malignant Transformation Diagnosis and Oral Cancer Prognosis Monitoring

NCT05942794Not ApplicableRecruitingPrimary

Identification of Oral Lesions Through an Autofluorescence System

NCT06256809Not Yet RecruitingPrimary

Analyzing Handprint Patterns to Predict Oral Cancer Risks: A Comparative Study

NCT04079491Terminated

Intra and Extra Oral Inspection of Oral Mucosa

NCT05505539Phase 1WithdrawnPrimary

Intralesional 5-fluorouracil Injection for the Treatment of Oral Leukoplakia

NCT00099021Phase 2Completed

Pioglitazone Hydrochloride in Preventing Head and Neck Cancer in Patients With Oral Leukoplakia

NCT04732741Unknown

Diagnostic Accuracy of Salivary Gamma-synuclein in Oral Malignant and Premalignant Lesions

NCT04712929CompletedPrimary

Candida Associated Cytokines in Oral Leukoplakia

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