Key Insights

Highlights

Success Rate

67% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

12.2%

5 terminated out of 41 trials

Success Rate

66.7%

-19.8% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

20%

2 of 10 completed with results

Key Signals

2 with results67% success

Data Visualizations

Phase Distribution

31Total
Not Applicable (6)
Early P 1 (2)
P 1 (8)
P 2 (15)

Trial Status

Recruiting11
Completed10
Unknown7
Terminated5
Not Yet Recruiting3
Active Not Recruiting2

Trial Success Rate

66.7%

Benchmark: 86.5%

Based on 10 completed trials

Clinical Trials (41)

Showing 20 of 20 trials
NCT07058805Phase 2Recruiting

Compartmentalized Postoperative Radiotherapy in Head and Neck Cancer

NCT05681039Phase 2Recruiting

Phase 2 Trial of Neoadjuvant and Adjuvant Tiragolumab Plus Atezolizumab in Patients With Newly Diagnosed PD-L1 CPS Positive Resectable Stage 3-4 Oral Cavity Squamous Cell Carcinoma (OCSCC).

NCT06532279Phase 2Recruiting

Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

NCT04333537Phase 2Recruiting

Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer

NCT06662058Not ApplicableRecruiting

Remote Audiometry to Monitor for Treatment-Related Hearing Loss in Patients With H&N SCC Receiving Cisplatin and/or Radiation

NCT06980038Phase 2Recruiting

Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer

NCT07529769Not Yet Recruiting

Artificial Intelligence for the Diagnosis of Oral Lesions

NCT06097468Phase 1RecruitingPrimary

Nisin in Oral Cavity Squamous Cell Carcinoma (OCSCC)

NCT04858269Phase 2Recruiting

First Line Weekly Chemo/Immunotherapy for Metastatic Head/Neck Squamous Cell Carcinoma Patients

NCT07484139Phase 2Not Yet RecruitingPrimary

H&N NEO-COMBAT XL: Neoadjuvant XL-092 (Zanzalintinib) and Pembrolizumab (Keytruda) in Surgically Resectable, HPV Negative Oral Cavity Squamous Cell Carcinoma (OCSCC)

NCT06947668Recruiting

Immune Biomarker Study for Cisplatin-ineligible Patients Receiving Chemoradiotherapy With Docetaxel

NCT05316688Phase 1TerminatedPrimary

A Fluorescent Tumor Marking Agent, Tozuleristide, for Imaging Oral Cavity Squamous Cell Cancer and High-Grade Oral Cavity Dysplasia During Surgery

NCT03258554Phase 2Completed

Radiation Therapy With Durvalumab or Cetuximab in Treating Patients With Locoregionally Advanced Head and Neck Cancer Who Cannot Take Cisplatin

NCT07335380Phase 1Not Yet RecruitingPrimary

Lattice-Based Radiotherapy and Chemo-Immunotherapy for Oral Cavity Squamous Cell Carcinoma

NCT04801472Not ApplicableTerminated

Optimisation of Potential Dental Implant Sites Protection for Rehabilitation in Patients With Head and Neck Cancer: Impact of Virtual Implants Visualisation on Dosimetry (OPPIDOM)

NCT04445064Phase 2Terminated

Activity and Safety of Peptide-based Immunotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck.

NCT03381183Phase 1Completed

IRX-2 Regimen and Durvalumab, for Incurable H&N Squamous Cell Carcinoma

NCT04725396Not ApplicableCompleted

Study Comparing Fibula Free-flap MR With or Without PVP in Patients With OOPC

NCT07121595Phase 2RecruitingPrimary

Personalized Neck Radiation Therapy Directed by Sentinel Lymph Node Biopsy for the Treatment of Oral Cavity Squamous Cell Carcinoma, PRECEDENT Trial

NCT03854032Phase 2Active Not Recruiting

Nivolumab and BMS986205 in Treating Patients With Stage II-IV Squamous Cell Cancer of the Head and Neck

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