Key Insights

Highlights

Success Rate

64% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 77/100

Termination Rate

22.2%

4 terminated out of 18 trials

Success Rate

63.6%

-22.9% vs benchmark

Late-Stage Pipeline

11%

2 trials in Phase 3/4

Results Transparency

14%

1 of 7 completed with results

Key Signals

1 with results64% success

Data Visualizations

Phase Distribution

15Total
Not Applicable (2)
Early P 1 (2)
P 1 (3)
P 2 (6)
P 3 (2)

Trial Status

Completed7
Terminated4
Unknown3
Active Not Recruiting2
Withdrawn1
Recruiting1

Trial Success Rate

63.6%

Benchmark: 86.5%

Based on 7 completed trials

Clinical Trials (18)

Showing 18 of 18 trials
NCT03180502Phase 2Active Not Recruiting

Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma

NCT04623931Phase 2Recruiting

Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) Glioblastomas

NCT07031765Phase 1Active Not Recruiting

Peds CHAMP1ON - Hematopoietic Stem Cell And Monoclonal Antibody PD-1 Blockade for RecurreNt Pediatric High-Grade Glioma

NCT01849952Terminated

Evaluating the Expression Levels of MicroRNA-10b in Patients With Gliomas

NCT02530320Phase 2Completed

Safety and Efficacy of PD0332991 (Palbociclib), a Cyclin-dependent Kinase 4 and 6 Inhibitor, in Patients With Oligodendroglioma or Recurrent Oligoastrocytoma Anaplastic With the Activity of the Protein RB Preserved

NCT00303849Phase 1Completed

Carboplatin, Melphalan, Etoposide Phosphate, Mannitol, and Sodium Thiosulfate in Treating Patients With Previously Treated Brain Tumors

NCT03353896Not ApplicableWithdrawn

NovoTTF-200A Device in Treating Patients With Newly Diagnosed High Risk Oligodendroglioma

NCT02903784Not ApplicableCompletedPrimary

Neural Basis of Language Processing

NCT00795457Early Phase 1Completed

Effects of Vaccinations With HLA-A2-Restricted Glioma Antigen-Peptides in Combination With Poly-ICLC for Adults With High-Risk WHO Grade II Astrocytomas and Oligo-Astrocytomas

NCT02209428Phase 2Unknown

A Prospective Cohort to Study the Effect of Temozolomide on IDH Mutational Low Grade Gliomas

NCT01281982Terminated

(11C)dLop as a Marker of P-Glycoprotein Function in Patients With Gliomas

NCT00874861Early Phase 1Completed

HLA-A2-Restricted Glioma Antigen-Peptides Vaccinations With Poly-ICLC for Recurrent WHO Grade II Gliomas

NCT01089244Unknown

FET-PET for Diagnosis and Monitoring in Patients With Low Grade Glioma

NCT00897377Phase 3Terminated

Treatment Strategy for Low-grade Gliomas

NCT00389090Phase 2Terminated

A Phase II Study of Temozolomide and O6-Benzylguanine (O6-BG) in Patients With Temozolomide-Resistant Anaplastic Glioma

NCT00089427Phase 1Completed

IL13-PE38QQR Infusion After Tumor Resection, Followed by Radiation Therapy With or Without Temozolomide in Patients With Newly Diagnosed Malignant Glioma

NCT00114309Phase 2Unknown

131-I-TM-601 Study in Adults With Recurrent High-Grade Glioma

NCT00717210Phase 3Completed

Randomized Phase III Study of Sequential Radiochemotherapy of Anaplastic Glioma With PCV or Temozolomide

Showing all 18 trials

Research Network

Activity Timeline