Key Insights

Highlights

Success Rate

70% trial completion

Published Results

42 trials with published results (8%)

Research Maturity

127 completed trials (23% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

10.0%

54 terminated out of 542 trials

Success Rate

70.2%

-16.4% vs benchmark

Late-Stage Pipeline

9%

49 trials in Phase 3/4

Results Transparency

33%

42 of 127 completed with results

Key Signals

42 with results70% success54 terminated

Data Visualizations

Phase Distribution

444Total
Not Applicable (52)
Early P 1 (7)
P 1 (151)
P 2 (185)
P 3 (38)
P 4 (11)

Trial Status

Recruiting135
Completed127
Unknown101
Not Yet Recruiting57
Terminated54
Active Not Recruiting49

Trial Success Rate

70.2%

Benchmark: 86.5%

Based on 127 completed trials

Clinical Trials (542)

Showing 20 of 20 trials
NCT02905591Phase 2Active Not Recruiting

A Phase 2 Study Adding Ascorbate to Chemotherapy and Radiation Therapy for NSCLC

NCT03526835Phase 1Recruiting

A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors

NCT05463224Phase 2Active Not RecruitingPrimary

Lazertinib for NSCLC Harboring Activating EGFR Mutations in TKI naïve Patients

NCT03744715Phase 2TerminatedPrimary

A Study to Allow Continued Dosing and/or Follow-up of Patients Who Have Had Previous Exposure to Poziotinib

NCT07729670Phase 2Not Yet RecruitingPrimary

Multimodal Ablation Combined With Perioperative Tislelizumab and Chemotherapy for Resectable II-IIIB NSCLC

NCT06944470Phase 2Active Not RecruitingPrimary

JS207 Combined With Chemotherapy in Subjects With Stage II-III NSCLC

NCT05378763Phase 3SuspendedPrimary

A Study of Poziotinib in Previously Treated Participants With Locally Advanced or Metastatic NSCLC Harboring HER2 Exon 20 Mutations

NCT07689812Not ApplicableNot Yet Recruiting

A Multicenter Randomized Open-Label Trial Evaluating ctDNA-Guided Interruption Versus Standard of Care Immune-Checkpoint Inhibitor (ICI) Therapy In Patients With Advanced / Metastatic Solid Tumors.

NCT06738160Phase 2RecruitingPrimary

The Efficacy and Safety of Narlumosbart in Combination With Stereotactic Body Radiation Therapy to Improve the Efficacy of First-line Chemotherapy Combined With Immunotherapy in Patients With Bone Metastases From Advanced Non-small Cell Lung Cancer

NCT05256290Phase 1Active Not Recruiting

Phase 1/2 Study of Silevertinib (BDTX-1535) in Patients With Glioblastoma or Non-Small Cell Lung Cancer With EGFR Mutations

NCT06881784Phase 3Recruiting

Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)

NCT06422143Phase 3Recruiting

Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023]

NCT07397338Phase 1Recruiting

Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Solid Tumors

NCT07671092Early Phase 1Not Yet Recruiting

Imaging Study in Metastatic UC, HR+ and HER2- Breast Cancer, TNBC, and NSCLC

NCT07697586Phase 2Not Yet RecruitingPrimary

SKB264 in Combination With SKB118 for Non-Small Cell Lung Cancer

NCT05787587Phase 1Active Not Recruiting

A Study of PARG Inhibitor IDE161 in Participants With Advanced Solid Tumors

NCT07349537Phase 1Recruiting

Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors

NCT04764188Active Not RecruitingPrimary

An Observational Study to Evaluate the Real-World Clinical Management and Outcomes of ALK-Positive Advanced NSCLC Participants Treated With Alectinib

NCT07692048Phase 1Not Yet RecruitingPrimary

A Phase Ib Study of Tislelizumab Plus SYS6010 in Immunotherapy-Pretreated Locally Advanced or Metastatic NSCLC

NCT04328844Phase 1Active Not Recruiting

A Study to Assess a PI3Kδ Inhibitor (IOA-244) in Patients With Metastatic Cancers

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