Key Insights

Highlights

Success Rate

70% trial completion

Published Results

38 trials with published results (7%)

Research Maturity

122 completed trials (23% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

9.9%

52 terminated out of 526 trials

Success Rate

70.1%

-16.4% vs benchmark

Late-Stage Pipeline

9%

49 trials in Phase 3/4

Results Transparency

31%

38 of 122 completed with results

Key Signals

38 with results70% success52 terminated

Data Visualizations

Phase Distribution

431Total
Not Applicable (49)
Early P 1 (5)
P 1 (151)
P 2 (177)
P 3 (38)
P 4 (11)

Trial Status

Recruiting135
Completed122
Unknown102
Terminated52
Not Yet Recruiting49
Active Not Recruiting47

Trial Success Rate

70.1%

Benchmark: 86.5%

Based on 122 completed trials

Clinical Trials (526)

Showing 20 of 20 trials
NCT06343402Phase 1Recruiting

Open-label Study of BBO-8520 in Adult Subjects With KRASG12C Non-small Cell Lung Cancer

NCT06685718Phase 1Active Not Recruiting

A Study Investigating BG-60366 in Adults With Epidermal Growth Factor Receptor (EGFR)-Mutant Non-Small Cell Lung Cancer

NCT05581004Phase 1Recruiting

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of Enzelkitug as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors

NCT07530744Not ApplicableNot Yet RecruitingPrimary

Post-Market Registry of Transbronchial Cryo-assisted RFA During Routine Standard Bronchoscopic Tumor Stagng and Resection

NCT07530276Active Not RecruitingPrimary

A Prospective Observational Study of Changes in Cortisol Levels After Neoadjuvant Immunotherapy and Their Prognostic Value in Patients With NSCLC

NCT00280189SuspendedPrimary

Study of Outcomes of Radiofrequency Ablation of Lung Tumors

NCT05059522Phase 3Active Not Recruiting

Continued Access Study for Participants Deriving Benefit in Pfizer-Sponsored Avelumab Parent Studies That Are Closing

NCT06362369Phase 1Recruiting

A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

NCT06865339Phase 2RecruitingPrimary

Thoracic Radiotherapy and Inhibition of PD-1 and LAG-3 for Locally Advanced Non-Small Cell Lung Cancer

NCT04764188Active Not RecruitingPrimary

An Observational Study to Evaluate the Real-World Clinical Management and Outcomes of ALK-Positive Advanced NSCLC Participants Treated With Alectinib

NCT06403436Phase 1Active Not Recruiting

A Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of TT125-802 in Subjects With Advanced Solid Tumors

NCT06248606Phase 2Recruiting

Adagrasib + SRS for Patients With Metastatic KRAS G12C-mutated NSCLC With Untreated Brain Metastases

NCT05987644Phase 1Recruiting

Delayed or Upfront Brain RAdiotherapy in Treatment naïve Lung Cancer Patients With Asymptomatic or Minimally Symptomatic Brain Metastases and ALK rEarrangements

NCT06422143Phase 3Recruiting

Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023]

NCT04665206Phase 1Recruiting

Study to Evaluate VT3989 in Patients With Metastatic Solid Tumors

NCT04245514Phase 2Active Not Recruiting

Multimodality Treatment in Stage III Non-small Cell Lung Cancer (NSCLC)

NCT04328844Phase 1Active Not Recruiting

A Study to Assess a PI3Kδ Inhibitor (IOA-244) in Patients With Metastatic Cancers

NCT07397338Phase 1Recruiting

Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Solid Tumors

NCT05837767Not ApplicableRecruiting

A Study of Radiation Therapy to Treat Solid Tumor Cancer That Has Spread to Soft Tissue

NCT05160922Phase 4Active Not RecruitingPrimary

Crizotinib Continuation Clinical Study

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