Key Insights

Highlights

Success Rate

88% trial completion (above average)

Published Results

34 trials with published results (35%)

Research Maturity

61 completed trials (62% of total)

Clinical Risk Assessment

Based on trial outcomes

Low Risk

Score: 17/100

Termination Rate

8.2%

8 terminated out of 98 trials

Success Rate

88.4%

+1.9% vs benchmark

Late-Stage Pipeline

29%

28 trials in Phase 3/4

Results Transparency

56%

34 of 61 completed with results

Key Signals

34 with results88% success

Data Visualizations

Phase Distribution

75Total
Not Applicable (4)
P 1 (8)
P 2 (35)
P 3 (25)
P 4 (3)

Trial Status

Completed61
Unknown14
Terminated8
Recruiting7
Active Not Recruiting3
Not Yet Recruiting3

Trial Success Rate

88.4%

Benchmark: 86.5%

Based on 61 completed trials

Clinical Trials (98)

Showing 20 of 20 trials
NCT06491862RecruitingPrimary

RACE-2L: Real-World Assessment of Clinical Practice and Outcomes in Non-squamous NSCLC After Failure of Platinum-based Chemotherapy in Brazil

NCT07005102Phase 2RecruitingPrimary

A Study to Assess Adverse Events, Change in Disease Activity of Intravenous Telisotuzumab Adizutecan in Combination With Osimertinib as First-Line Treatment in Adult Participants With Locally Advanced Unresectable or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer

NCT06627647Phase 3RecruitingPrimary

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Metastatic Non-squamous NSCLC

NCT06396065Phase 3Active Not RecruitingPrimary

Phase III Study of AK112 for NSCLC Patients

NCT06173505Phase 1TerminatedPrimary

Study of Vudalimab or Pembrolizumab in Combination With Chemotherapy as First-line Treatment in Patients With Advanced NSCLC

NCT07264816Phase 2RecruitingPrimary

A Study of BL-M07D1 in Combination With Pembrolizumab in Patients With Unresectable Locally Advanced or Metastatic HER2-Overexpressing Non-Squamous NSCLC

NCT05184712Phase 3Active Not RecruitingPrimary

Phase 3 Clinical Study of AK112 for NSCLC Patients

NCT03829319Phase 3CompletedPrimary

Safety and Efficacy Study of Pemetrexed + Platinum Chemotherapy + Pembrolizumab (MK-3475) With or Without Lenvatinib (MK-7902/E7080) as First-line Intervention in Adults With Metastatic Nonsquamous Non-small Cell Lung Cancer (MK-7902-006/E7080-G000-315/LEAP-006)

NCT07178795Phase 3RecruitingPrimary

A Study of BL-M07D1 vs Pembrolizumab-platinum Chemotherapy in First-line Treatment of HER2-mutant Advanced or Metastatic Non-squamous NSCLC

NCT05317078Phase 1TerminatedPrimary

A Phase 1 Safety, Tolerability, and Pharmacokinetics Study of AMG 794 With Claudin 6-positive Non-small Cell Lung Cancer, Epithelial Ovarian Cancer, and Other Malignant Solid Tumor Indications

NCT04716933Phase 3CompletedPrimary

Safety and Efficacy Study of Pemetrexed + Platinum Chemotherapy + Pembrolizumab (MK-3475) With or Without Lenvatinib (MK-7902/E7080) as First-line Intervention in Adults With Metastatic Nonsquamous Non-small Cell Lung Cancer (MK-7902-006/E7080-G000-315/LEAP-006)-China Extension Study

NCT05245071Phase 2TerminatedPrimary

Tusamitamab Ravtansine in NSQ NSCLC Participants With Negative or Moderate CEACAM5 Expression Tumors and High Circulating CEA

NCT06417008Phase 2RecruitingPrimary

A Study of HS-20117 Combined With Aumolertinib in Participants With Advanced Non-Squamous Non-Small Cell Lung Cancer

NCT06868836Phase 2RecruitingPrimary

A Study of JS207 (PD-1/VEGF Bispecific Antibody) in Combination With Chemotherapy in Advanced Non-small Cell Lung Cancer

NCT06643117Phase 3Terminated

Similar Efficacy, Safety, and Immunogenicity of FYB206 in Comparison to Keytruda as add-on to Chemotherapy in Patients With Non-squamous Non-small Cell Lung Cancer (NSCLC)

NCT04206787CompletedPrimary

The Study Observes Afatinib as First-line Treatment in Patients With Epidermal Growth Factor Receptor (EGFR) Mutation-positive Advanced Non-small Cell Lung Cancer

NCT06847334Phase 3Not Yet RecruitingPrimary

A Study to Compare the Efficacy, Safety, Immunogenicity, and Pharmacokinetic Profile of HLX17 Vs. Keytruda® in the First-Line Treatment of Advanced Non-squamous Non-small Cell Lung Cancer

NCT05338970Phase 3Active Not RecruitingPrimary

HERTHENA-Lung02: A Study of Patritumab Deruxtecan Versus Platinum-based Chemotherapy in Metastatic or Locally Advanced EGFRm NSCLC After Failure of EGFR TKI Therapy

NCT04795245CompletedPrimary

Non-interventional Study for Real-world Data of Afatinib Treatment in First-line Setting and of Subsequent Therapies for Patients With Advanced Epidermal Growth Factor Receptor (EGFR) Mutation-positive Lung Adenocarcinoma

NCT06724263Phase 2Not Yet Recruiting

A Multicenter, Open-label Phase IIa Clinical Study to Evaluate the Efficacy and Safety of B1962 Injection in the Treatment of Advanced Malignant Solid Tumors

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