Key Insights

Highlights

Success Rate

74% trial completion

Published Results

26 trials with published results (17%)

Research Maturity

60 completed trials (40% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

14.0%

21 terminated out of 150 trials

Success Rate

74.1%

-12.4% vs benchmark

Late-Stage Pipeline

16%

24 trials in Phase 3/4

Results Transparency

43%

26 of 60 completed with results

Key Signals

26 with results74% success21 terminated

Data Visualizations

Phase Distribution

130Total
Not Applicable (11)
Early P 1 (2)
P 1 (35)
P 2 (58)
P 3 (16)
P 4 (8)

Trial Status

Completed60
Unknown36
Terminated21
Recruiting15
Active Not Recruiting7
Not Yet Recruiting5

Trial Success Rate

74.1%

Benchmark: 86.5%

Based on 60 completed trials

Clinical Trials (150)

Showing 20 of 20 trials
NCT07185997Phase 3RecruitingPrimary

Study to Evaluate Efficacy and Safety of Firmonertinib Compared With Investigator's Choice of EGFR Inhibitor as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic NSCLC With EGFR P-Loop and Alpha C-Helix Compressing (PACC) Uncommon Mutations

NCT02609776Phase 1Active Not RecruitingPrimary

Study of Amivantamab, a Human Bispecific EGFR and cMet Antibody, in Participants With Advanced Non-Small Cell Lung Cancer

NCT05355701Phase 1Recruiting

A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.

NCT04895709Phase 1Recruiting

A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors

NCT07599163Not ApplicableNot Yet RecruitingPrimary

Oral Paclitaxel as Neoadjuvant Therapy in Elderly NSCLC: A Phase II Trial

NCT04768075Phase 3CompletedPrimary

Camrelizumab Combined With SRT/WBRT and Chemotherapy in Patients With Brain Metastases of Driven Gene-negative NSCLC

NCT07094204Phase 1Recruiting

A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors

NCT07559526CompletedPrimary

Nutritional Assessment of Patients With Non-small Cell Lung Cancer Treated With Osimertinib

NCT04181788Phase 1Active Not Recruiting

Sasanlimab (PF-06801591, PD-1 Inhibitor) in Participants With Advanced Malignancies

NCT06281964Phase 3Enrolling By InvitationPrimary

Efficacy and Safety Evaluation of PLB1004 in Patients With Non-squamous NSCLC Harboring EGFR Exon 20 Insertion.

NCT04849481RecruitingPrimary

The Research Plan of Taiwan Precision Medicine

NCT03860272Phase 1Active Not Recruiting

Fc-Engineered Anti-CTLA-4 Monoclonal Antibody in Advanced Cancer

NCT07336732Phase 2RecruitingPrimary

Andamertinib With or Without Platinum-doublet Chemotherapy Versus Platinum-doublet Chemotherapy in Patients With NSCLC Harboring Atypical EGFR Mutations

NCT06245837Active Not RecruitingPrimary

Treatment and Biomarker Testing Patterns,Treatment Outcomes in a/m NSCLC With and Without Actionable Genomic Alterations

NCT06546553Phase 1Terminated

A Study to Learn About How Different Amounts of the Study Medicine PF-07826390 Act in the Body of People With Cancer When Taken Alone or With Other Anti-cancer Medicines.

NCT06813365Phase 1RecruitingPrimary

Assessing an Oral EGFR Inhibitor, DZD6008 in Patients Who Have Advanced NSCLC With EGFR Mutations (TIAN-SHAN2)

NCT05144997Phase 4Active Not RecruitingPrimary

Lorlatinib Continuation Study

NCT04681131Phase 2CompletedPrimary

CAB-AXL-ADC Safety and Efficacy Study in Adults With NSCLC

NCT06285097Phase 1Terminated

A Study of PF-07820435 as a Single Agent and in Combination in Participants With Advanced Solid Tumors

NCT04547504Phase 3Active Not RecruitingPrimary

PEmbRolizumab verSus chEmotherapy and pEmbrolizumab in Non-small-cell Lung Cancers (NSCLC) With PDL1 ≥ 50 %

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