Key Insights

Highlights

Success Rate

74% trial completion

Published Results

26 trials with published results (17%)

Research Maturity

61 completed trials (40% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

13.9%

21 terminated out of 151 trials

Success Rate

74.4%

-12.2% vs benchmark

Late-Stage Pipeline

16%

24 trials in Phase 3/4

Results Transparency

43%

26 of 61 completed with results

Key Signals

26 with results74% success21 terminated

Data Visualizations

Phase Distribution

131Total
Not Applicable (11)
Early P 1 (2)
P 1 (36)
P 2 (58)
P 3 (16)
P 4 (8)

Trial Status

Completed61
Unknown36
Terminated21
Recruiting15
Active Not Recruiting7
Not Yet Recruiting5

Trial Success Rate

74.4%

Benchmark: 86.6%

Based on 61 completed trials

Clinical Trials (151)

Showing 20 of 20 trials
NCT02609776Phase 1Active Not RecruitingPrimary

Study of Amivantamab, a Human Bispecific EGFR and cMet Antibody, in Participants With Advanced Non-Small Cell Lung Cancer

NCT05144997Phase 4Active Not RecruitingPrimary

Lorlatinib Continuation Study

NCT07185997Phase 3RecruitingPrimary

Study to Evaluate Efficacy and Safety of Firmonertinib Compared With Investigator's Choice of EGFR Inhibitor as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic NSCLC With EGFR P-Loop and Alpha C-Helix Compressing (PACC) Uncommon Mutations

NCT05355701Phase 1Active Not Recruiting

A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.

NCT06813365Phase 1RecruitingPrimary

Assessing an Oral EGFR Inhibitor, DZD6008 in Patients Who Have Advanced NSCLC With EGFR Mutations (TIAN-SHAN2)

NCT04895709Phase 1Recruiting

A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors

NCT07655622Phase 1RecruitingPrimary

Vebreltinib Plus Furmonertinib in Patients With EGFR-mutated Advanced Non-small Cell Lung Cancer and High PD-L1 Expression

NCT04181788Phase 1Completed

Sasanlimab (PF-06801591, PD-1 Inhibitor) in Participants With Advanced Malignancies

NCT06245837Active Not RecruitingPrimary

Treatment and Biomarker Testing Patterns,Treatment Outcomes in a/m NSCLC With and Without Actionable Genomic Alterations

NCT07599163Not ApplicableNot Yet RecruitingPrimary

Oral Paclitaxel as Neoadjuvant Therapy in Elderly NSCLC: A Phase II Trial

NCT04768075Phase 3CompletedPrimary

Camrelizumab Combined With SRT/WBRT and Chemotherapy in Patients With Brain Metastases of Driven Gene-negative NSCLC

NCT07094204Phase 1Recruiting

A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors

NCT07559526CompletedPrimary

Nutritional Assessment of Patients With Non-small Cell Lung Cancer Treated With Osimertinib

NCT06281964Phase 3Enrolling By InvitationPrimary

Efficacy and Safety Evaluation of PLB1004 in Patients With Non-squamous NSCLC Harboring EGFR Exon 20 Insertion.

NCT04849481RecruitingPrimary

The Research Plan of Taiwan Precision Medicine

NCT03860272Phase 1Active Not Recruiting

Fc-Engineered Anti-CTLA-4 Monoclonal Antibody in Advanced Cancer

NCT07336732Phase 2RecruitingPrimary

Andamertinib With or Without Platinum-doublet Chemotherapy Versus Platinum-doublet Chemotherapy in Patients With NSCLC Harboring Atypical EGFR Mutations

NCT06546553Phase 1Terminated

A Study to Learn About How Different Amounts of the Study Medicine PF-07826390 Act in the Body of People With Cancer When Taken Alone or With Other Anti-cancer Medicines.

NCT04681131Phase 2CompletedPrimary

CAB-AXL-ADC Safety and Efficacy Study in Adults With NSCLC

NCT04547504Phase 3Active Not RecruitingPrimary

PEmbRolizumab verSus chEmotherapy and pEmbrolizumab in Non-small-cell Lung Cancers (NSCLC) With PDL1 ≥ 50 %

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