NF1
17
2
7
4
Key Insights
Highlights
Success Rate
57% trial completion
Clinical Risk Assessment
Based on trial outcomes
High Risk
Score: 60/100
17.6%
3 terminated out of 17 trials
57.1%
-29.4% vs benchmark
6%
1 trials in Phase 3/4
125%
5 of 4 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 4 completed trials
Clinical Trials (17)
AZD6244 Hydrogen Sulfate for Children With Nervous System Tumors
Trial of Selumetinib and Bromodomain Inhibitor With Durvalumab for Sarcomas
Interventions for Reading Disabilities in NF1
A Study of Avutometinib for People With Solid Tumor Cancers
Feasibility and Tolerability of IMLYGIC for the Treatment of Cutaneous Neurofibromas in Adults With NF1
Mirdametinib Monotherapy in Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF).
Developing Biomarkers of Plexiform Tumor Burden in Patients With Neurofibromatosis-Type 1
Follow-up Study to Evaluate the Safety and Efficacy of FCN-159 in Pediatric Participants With Neurofibromatosis Type 1
A Phase II Trial of Poly-ICLC for Low-Grade Gliomas
FCN-159 in Adult Patients With Symptomatic, Inoperable Neurofibromatosis Type 1-Related Plexiform Neurofibromas
Study to Evaluate the Safety, Tolerability, PK Characteristics and Anti-tumor Activity of FCN-159 in Adult and Pediatric Participants With Neurofibromatosis Type 1
Cabozantinib for Plexiform Neurofibromas (PN) in Subjects With NF1 in Children and Adults
A Study of INFUSE Bone Graft (BMP-2) in the Treatment of Tibial Pseudarthrosis in Neurofibromatosis Type 1 (NF1)
Study of Plexiform Neurofibromas in Neurofibromatosis Type 1
Adaptation and Quality of Life Among Adults With Neurofibromatosis Type I
Study of Sutent®/Sunitinib (SU11248) in Subjects With NF-1 Plexiform Neurofibromas
Study of Tasigna®/Nilotinib (AMN107) in Neurofibromatosis (NF1) Patients With Plexiform Neurofibromas