NF1
17
3
7
4
Key Insights
Highlights
Success Rate
57% trial completion
Clinical Risk Assessment
Based on trial outcomes
High Risk
Score: 60/100
17.6%
3 terminated out of 17 trials
57.1%
-29.4% vs benchmark
6%
1 trials in Phase 3/4
125%
5 of 4 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 4 completed trials
Clinical Trials (17)
AZD6244 Hydrogen Sulfate for Children With Nervous System Tumors
Mirdametinib Monotherapy in Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF).
A Study of Avutometinib for People With Solid Tumor Cancers
Feasibility and Tolerability of IMLYGIC for the Treatment of Cutaneous Neurofibromas in Adults With NF1
Trial of Selumetinib and Bromodomain Inhibitor With Durvalumab for Sarcomas
Developing Biomarkers of Plexiform Tumor Burden in Patients With Neurofibromatosis-Type 1
Interventions for Reading Disabilities in NF1
Follow-up Study to Evaluate the Safety and Efficacy of FCN-159 in Pediatric Participants With Neurofibromatosis Type 1
A Phase II Trial of Poly-ICLC for Low-Grade Gliomas
FCN-159 in Adult Patients With Symptomatic, Inoperable Neurofibromatosis Type 1-Related Plexiform Neurofibromas
Study to Evaluate the Safety, Tolerability, PK Characteristics and Anti-tumor Activity of FCN-159 in Adult and Pediatric Participants With Neurofibromatosis Type 1
Cabozantinib for Plexiform Neurofibromas (PN) in Subjects With NF1 in Children and Adults
A Study of INFUSE Bone Graft (BMP-2) in the Treatment of Tibial Pseudarthrosis in Neurofibromatosis Type 1 (NF1)
Study of Plexiform Neurofibromas in Neurofibromatosis Type 1
Adaptation and Quality of Life Among Adults With Neurofibromatosis Type I
Study of Sutent®/Sunitinib (SU11248) in Subjects With NF-1 Plexiform Neurofibromas
Study of Tasigna®/Nilotinib (AMN107) in Neurofibromatosis (NF1) Patients With Plexiform Neurofibromas