Key Insights

Highlights

Success Rate

50% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

18.8%

3 terminated out of 16 trials

Success Rate

50.0%

-36.5% vs benchmark

Late-Stage Pipeline

13%

2 trials in Phase 3/4

Results Transparency

67%

2 of 3 completed with results

Key Signals

2 with results50% success

Data Visualizations

Phase Distribution

12Total
Not Applicable (2)
P 1 (7)
P 2 (1)
P 3 (2)

Trial Status

Recruiting4
Unknown4
Completed3
Terminated3
Withdrawn2

Trial Success Rate

50.0%

Benchmark: 86.5%

Based on 3 completed trials

Clinical Trials (16)

Showing 16 of 16 trials
NCT03911388Phase 1Recruiting

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

NCT05592743Unknown

Vorasidenib Expanded Access Program

NCT06496971Phase 3Recruiting

A Prospective Pivotal Study to Evaluate the Efficacy and Safety of Avastin® Bevacizumab (BEV) With or Without Microbubble-mediated Focused Ultrasound (FUS-MB) Using NaviFUS System in Recurrent Glioblastoma Multiforme Patients

NCT04446416Not ApplicableCompleted

Efficacy and Safety of NaviFUS System add-on Bevacizumab (BEV) in Recurrent GBM Patients

NCT06329570Phase 1Recruiting

Safety and Efficacy of Bevacizumab in Combination With NaviFUS System for the Treatment of Recurrent Glioblastoma Multiforme (rGBM)

NCT04222972Phase 3Terminated

A Study of Pralsetinib Versus Standard of Care for First-Line Treatment of Advanced Non-Small Cell Lung Cancer (NSCLC)

NCT03037385Phase 1Completed

Phase 1/2 Study of the Highly-selective RET Inhibitor, Pralsetinib (BLU-667), in Participants With Thyroid Cancer, Non-Small Cell Lung Cancer, and Other Advanced Solid Tumors

NCT04862780Phase 1Terminated

(SYMPHONY) Phase 1/2 Study Targeting EGFR Resistance Mechanisms in NSCLC

NCT05153408Phase 1Terminated

(HARMONY) Study of BLU-701 in EGFR-mutant NSCLC

NCT04949282Recruiting

Spanish Series of Patients Treated With the Radionuclide Lutetium177

NCT04697446Unknown

External Control, Observational, Retrospective Study Comparing Pralsetinib to Best Available Therapy in Patients With RET-Fusion Positive NSCLC

NCT04388033Phase 1Unknown

Clinical Study of an Dendritic and Glioma Cells Fusion Vaccine With IL-12 for Treatment-naïve GBM Patients.

NCT03626896Not ApplicableCompleted

Safety of BBB Disruption Using NaviFUS System in Recurrent Glioblastoma Multiforme (GBM) Patients

NCT03109301Phase 2WithdrawnPrimary

Mitogen Activated Protein Kinase Kinase (MEK1/2) Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in People With Neurofibromatosis Type 1 (NF1) Mutated Gastrointestinal Stromal Tumors (GIST)

NCT02745756Phase 1Withdrawn

A Combined Cell Therapy Approach to the Treatment of Neuroblastoma

NCT01579253Unknown

Combined O-(2-[18F]Fluoroethyl)-L-tyrosine (FET) Positron Emission Tomography (PET) and Simultaneous Magnetic Resonance Imaging (MRI) Follow-up in Re-irradiated Recurrent Glioblastoma Patients

Showing all 16 trials

Research Network

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