Key Insights

Highlights

Success Rate

50% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

18.8%

3 terminated out of 16 trials

Success Rate

50.0%

-36.5% vs benchmark

Late-Stage Pipeline

13%

2 trials in Phase 3/4

Results Transparency

67%

2 of 3 completed with results

Key Signals

2 with results50% success

Data Visualizations

Phase Distribution

12Total
Not Applicable (2)
P 1 (7)
P 2 (1)
P 3 (2)

Trial Status

Unknown4
Recruiting4
Completed3
Terminated3
Withdrawn2

Trial Success Rate

50.0%

Benchmark: 86.5%

Based on 3 completed trials

Clinical Trials (16)

Showing 16 of 16 trials
NCT03911388Phase 1Recruiting

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

NCT06329570Phase 1Recruiting

Safety and Efficacy of Bevacizumab in Combination With NaviFUS System for the Treatment of Recurrent Glioblastoma Multiforme (rGBM)

NCT04446416Not ApplicableCompleted

Efficacy and Safety of NaviFUS System add-on Bevacizumab (BEV) in Recurrent GBM Patients

NCT06496971Phase 3Recruiting

A Prospective Pivotal Study to Evaluate the Efficacy and Safety of Avastin® Bevacizumab (BEV) With or Without Microbubble-mediated Focused Ultrasound (FUS-MB) Using NaviFUS System in Recurrent Glioblastoma Multiforme Patients

NCT04222972Phase 3Terminated

A Study of Pralsetinib Versus Standard of Care for First-Line Treatment of Advanced Non-Small Cell Lung Cancer (NSCLC)

NCT03037385Phase 1Completed

Phase 1/2 Study of the Highly-selective RET Inhibitor, Pralsetinib (BLU-667), in Participants With Thyroid Cancer, Non-Small Cell Lung Cancer, and Other Advanced Solid Tumors

NCT04862780Phase 1Terminated

(SYMPHONY) Phase 1/2 Study Targeting EGFR Resistance Mechanisms in NSCLC

NCT05592743Unknown

Vorasidenib Expanded Access Program

NCT05153408Phase 1Terminated

(HARMONY) Study of BLU-701 in EGFR-mutant NSCLC

NCT04949282Recruiting

Spanish Series of Patients Treated With the Radionuclide Lutetium177

NCT04697446Unknown

External Control, Observational, Retrospective Study Comparing Pralsetinib to Best Available Therapy in Patients With RET-Fusion Positive NSCLC

NCT04388033Phase 1Unknown

Clinical Study of an Dendritic and Glioma Cells Fusion Vaccine With IL-12 for Treatment-naïve GBM Patients.

NCT03626896Not ApplicableCompleted

Safety of BBB Disruption Using NaviFUS System in Recurrent Glioblastoma Multiforme (GBM) Patients

NCT03109301Phase 2WithdrawnPrimary

Mitogen Activated Protein Kinase Kinase (MEK1/2) Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in People With Neurofibromatosis Type 1 (NF1) Mutated Gastrointestinal Stromal Tumors (GIST)

NCT02745756Phase 1Withdrawn

A Combined Cell Therapy Approach to the Treatment of Neuroblastoma

NCT01579253Unknown

Combined O-(2-[18F]Fluoroethyl)-L-tyrosine (FET) Positron Emission Tomography (PET) and Simultaneous Magnetic Resonance Imaging (MRI) Follow-up in Re-irradiated Recurrent Glioblastoma Patients

Showing all 16 trials

Research Network

Activity Timeline