Key Insights

Highlights

Success Rate

40% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 75/100

Termination Rate

21.8%

12 terminated out of 55 trials

Success Rate

40.0%

-46.5% vs benchmark

Late-Stage Pipeline

7%

4 trials in Phase 3/4

Results Transparency

113%

9 of 8 completed with results

Key Signals

9 with results40% success12 terminated

Data Visualizations

Phase Distribution

47Total
Not Applicable (1)
P 1 (25)
P 2 (17)
P 3 (3)
P 4 (1)

Trial Status

Unknown14
Terminated12
Recruiting12
Completed8
Active Not Recruiting5
Not Yet Recruiting3

Trial Success Rate

40.0%

Benchmark: 86.5%

Based on 8 completed trials

Clinical Trials (55)

Showing 20 of 20 trials
NCT07574541Phase 2Not Yet Recruiting

Multitargeted Recombinant Ad5 PSA/MUC-1/Brachyury-Based Immunotherapy (TriAdeno) Vaccine With IL-15 Superagonist N-803 in Participants With Clinically Localized Prostate Cancer Undergoing Active Surveillance

NCT05797246Phase 2Active Not Recruiting

Bevacizumab in Adults With Recurrent Respiratory Papillomatosis (RRP)

NCT03911388Phase 1Recruiting

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

NCT05592743Unknown

Vorasidenib Expanded Access Program

NCT07075185Phase 1Recruiting

A Study to Evaluate a Novel Gene Therapy in Patients With Relapsed and Refractory Multiple Myeloma

NCT02690545Phase 1Active Not Recruiting

Study of CD30 CAR for Relapsed/Refractory CD30+ HL and CD30+ NHL

NCT02663297Phase 1Active Not Recruiting

Administration of T Lymphocytes for Prevention of Relapse of Lymphomas

NCT02158858Phase 1Completed

A Phase 1/2 Study of CPI-0610 With and Without Ruxolitinib in Patients With Hematologic and Myeloproliferative Malignancies

NCT06001788Phase 1Recruiting

Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia

NCT04222972Phase 3Terminated

A Study of Pralsetinib Versus Standard of Care for First-Line Treatment of Advanced Non-Small Cell Lung Cancer (NSCLC)

NCT07440290Phase 2Not Yet Recruiting

DETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Young Adult Patients With BRAF V600 Mutation-Positive Cancers.

NCT04124198Not ApplicableActive Not Recruiting

Quality of Life After Primary TORS vs IMRT for Patients With Early-stage Oropharyngeal Squamous Cell Carcinoma

NCT06988475Phase 2Recruiting

DETERMINE Trial Treatment Arm 06: Capmatinib in Adult Patients With Cancers Harbouring MET Dysregulations

NCT05770544Phase 2Recruiting

DETERMINE Trial Treatment Arm 03: Entrectinib in Adult, Paediatric and Teenage/Young Adult Patients With ROS1 Gene Fusion-Positive Cancers.

NCT05770037Phase 2Recruiting

DETERMINE Trial Treatment Arm 01: Alectinib in Adult, Paediatric and Teenage/Young Adult Patients With ALK Positive Cancers

NCT05770102Phase 2Recruiting

DETERMINE Trial Treatment Arm 02: Atezolizumab in Adult, Paediatric and Teenage/Young Adult Patients With Cancers With High Tumour Mutational Burden (TMB) or Microsatellite Instability-high (MSI-high) or Proven Constitutional Mismatch Repair Deficiency (CMMRD) Disposition

NCT04572451Phase 1Recruiting

Safety of SBRT With Anti-PD1 and Anti-IL-8 for the Treatment of Multiple Metastases in Advanced Solid Tumors and Melanoma

NCT03037385Phase 1Completed

Phase 1/2 Study of the Highly-selective RET Inhibitor, Pralsetinib (BLU-667), in Participants With Thyroid Cancer, Non-Small Cell Lung Cancer, and Other Advanced Solid Tumors

NCT03744676Phase 2Completed

A Safety Trial of Lisocabtagene Maraleucel (JCAR017) for Relapsed and Refractory (R/R) B-cell Non-Hodgkin Lymphoma (NHL) in the Outpatient Setting (TRANSCEND-OUTREACH-007)

NCT04249947Phase 1Terminated

P-PSMA-101 CAR-T Cells in the Treatment of Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC) and Advanced Salivary Gland Cancers (SGC)

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