Key Insights

Highlights

Success Rate

77% trial completion

Published Results

35 trials with published results (49%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 52/100

Termination Rate

21.1%

15 terminated out of 71 trials

Success Rate

76.6%

-9.9% vs benchmark

Late-Stage Pipeline

15%

11 trials in Phase 3/4

Results Transparency

71%

35 of 49 completed with results

Key Signals

35 with results77% success15 terminated

Data Visualizations

Phase Distribution

67Total
Not Applicable (4)
P 1 (21)
P 2 (31)
P 3 (11)

Trial Status

Completed49
Terminated15
Unknown3
Withdrawn2
Active Not Recruiting1
Recruiting1

Trial Success Rate

76.6%

Benchmark: 86.5%

Based on 49 completed trials

Clinical Trials (71)

Showing 20 of 20 trials
NCT04892342Phase 1CompletedPrimary

Study of ESG401 in Adults With Solid Tumors

NCT04915755Phase 3Active Not RecruitingPrimary

Efficacy and Safety Comparison of Niraparib to Placebo in Participants With Human Epidermal Growth Factor 2 Negative (HER2-) Breast Cancer Susceptibility Gene Mutation (BRCAmut) or Triple-Negative Breast Cancer (TNBC) With Molecular Disease

NCT00490139Phase 3CompletedPrimary

ALTTO (Adjuvant Lapatinib And/Or Trastuzumab Treatment Optimisation) Study; BIG 2-06/N063D

NCT01160211Phase 3CompletedPrimary

A Study to Compare the Safety and Efficacy of an Aromatase Inhibitor in Combination With Lapatinib, Trastuzumab or Both for the Treatment of Hormone Receptor Positive, HER2+ Metastatic Breast Cancer

NCT06819215Phase 1Recruiting

Phase I/II Clinical Study to Evaluate VB15010 Tablets in Patients With Advanced Solid Tumors

NCT03329937Phase 1CompletedPrimary

Study Evaluating the Antitumor Activity and Safety of Niraparib as Neoadjuvant Treatment in Participants With Breast Cancer

NCT04777786Not ApplicableTerminatedPrimary

Early Rehabilitation for Breast Cancer - A Randomized Control Trial

NCT00272987Phase 3TerminatedPrimary

ErbB2 Over-expressing Metastatic Breast Cancer Study Using Paclitaxel, Trastuzumab, and Lapatinib

NCT05814224Not ApplicableUnknown

Monitoring luminAl Breast Cancer Through the Evaluation of Mutational and epiGeNEtic alteraTIons of Circulating ESR1 DNA

NCT00251433Phase 1TerminatedPrimary

GW572016 With Docetaxel and Trastuzumab for the Treatment Of Untreated ErbB2 Over-Expressing Metastatic Breast Cancer

NCT00281658Phase 3CompletedPrimary

Study In Women And Men With Metastatic Breast Cancer That Have Overexpression Of ErbB2

NCT01905592Phase 3TerminatedPrimary

A Phase III Trial of Niraparib Versus Physician's Choice in HER2 Negative, Germline BRCA Mutation-positive Breast Cancer Patients

NCT02913729Not ApplicableTerminated

Pre- Versus Postoperative Accelerated Partial Breast Irradiation

NCT00444535Phase 2CompletedPrimary

Lapatinib and Bevacizumab for Metastatic Breast Cancer

NCT02213042Phase 2TerminatedPrimary

Evaluation of Biomarkers Associated With Response to Subsequent Therapies in Subjects With HER2-Positive Metastatic Breast Cancer

NCT00553358Phase 3CompletedPrimary

Neo ALTTO (Neoadjuvant Lapatinib and/or Trastuzumab Treatment Optimisation) Study

NCT00508274Phase 3TerminatedPrimary

Lapatinib +Capecitabine Treatment for Advanced Metastatic Breast Cancer in Women From China

NCT01220128Phase 2TerminatedPrimary

Evaluation of an Anti-cancer Immunotherapy Combined With Standard Neoadjuvant Treatment in Patients With WT1-positive Primary Invasive Breast Cancer

NCT00367471Phase 1CompletedPrimary

Combination Of Lapatinib With Carboplatin, Paclitaxel, and With or Without Trastuzumab In Metastatic Breast Cancer.

NCT01118624Phase 2Completed

Study of Pralatrexate in Female Patients With Previously-treated Breast Cancer

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