Key Insights

Highlights

Success Rate

70% trial completion

Published Results

16 trials with published results (23%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 74/100

Termination Rate

20.3%

14 terminated out of 69 trials

Success Rate

69.6%

-16.9% vs benchmark

Late-Stage Pipeline

6%

4 trials in Phase 3/4

Results Transparency

50%

16 of 32 completed with results

Key Signals

16 with results70% success14 terminated

Data Visualizations

Phase Distribution

52Total
Not Applicable (11)
P 1 (18)
P 2 (19)
P 3 (3)
P 4 (1)

Trial Status

Completed32
Terminated14
Recruiting11
Unknown4
Active Not Recruiting3
Withdrawn3

Trial Success Rate

69.6%

Benchmark: 86.5%

Based on 32 completed trials

Clinical Trials (69)

Showing 20 of 20 trials
NCT02320656Not ApplicableCompleted

Predictive Clinical and Biological Parameters in Acute Leukemia, Myelodysplastic Syndromes and Myeloproliferative Disorders-HEMATO-BIO-IPC-2013-015

NCT05088356Phase 1Recruiting

Reduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted Graft

NCT05969821Not Yet Recruiting

Clonal Hematopoiesis of Immunological Significance

NCT01366612Phase 3Terminated

PRO#1278: Fludarabine and Busulfan vs. Fludarabine, Busulfan and Total Body Irradiation

NCT07445438Not ApplicableRecruiting

Feasibility of a Multi-omics Platform for Hematological Malignancies

NCT07445984Not ApplicableRecruiting

Chemogenomic Profiling in Hematological Malignancies (HEM-Profiling 2021)

NCT07403630Not ApplicableRecruiting

INTEGRATIVE "MULTI-OMICS" AND FUNCTIONAL PLATFORM FOR THE COMPLETE DIAGNOSTIC CHARACTERIZATION OF TUMORS: THE ITALIAN TUMOR CHEMOGENOMIC PROFILER (IT-TCP)

NCT01728402Enrolling By Invitation

Pathogenesis of Hematologic Malignancies

NCT07362225Recruiting

MPN PROGRESSion Registry: Observational Study Tracking Symptoms, Treatments, and Disease Progression in People With Myeloproliferative Neoplasms (MPNs)

NCT07119970Not ApplicableRecruiting

Prognostic Value of NETosis Markers for Thrombosis During Myeloproliferative Neoplasms (AVATARE)

NCT06138587Phase 1Recruiting

Preemptive CIML NK Cell Therapy After Hematopoietic Stem Cell Transplantation

NCT03452774Recruiting

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

NCT02158858Phase 1Completed

A Phase 1/2 Study of CPI-0610 With and Without Ruxolitinib in Patients With Hematologic and Myeloproliferative Malignancies

NCT06265584Phase 2Recruiting

Trial of 2 Step ATG for Prevention of Acute GVHD Post Allogeneic Stem Cell Transplant

NCT06315309Phase 2Recruiting

Trial of 2 Step ATG for Acute GVHD Prevention Post Myeloablative Allogeneic Stem Cell Transplant

NCT05842603Not ApplicableRecruitingPrimary

I Can Move With Purpose Now! A Pilot Lifestyle Intervention Study in Myeloproliferative Neoplasm Patients

NCT05823571Phase 1Active Not Recruiting

Itacitinib With High-dose Posttransplantation Cyclophosphamide in Older Patients

NCT04717414Phase 3Active Not RecruitingPrimary

An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Subjects With Myeloproliferative Neoplasm-Associated Myelofibrosis on Concomitant JAK2 Inhibitor Therapy and Who Require Red Blood Cell Transfusions

NCT00452023Phase 2CompletedPrimary

Pegasys® in Patients With Myeloproliferative Diseases

NCT06481345Active Not RecruitingPrimary

Characterization of Myeloproliferative Neoplasia With a Mutated IDH, SRSF2 or SF3B1 Allele (CARPEDIEM)

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