Key Insights

Highlights

Success Rate

80% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 39/100

Termination Rate

4.8%

1 terminated out of 21 trials

Success Rate

80.0%

-6.5% vs benchmark

Late-Stage Pipeline

14%

3 trials in Phase 3/4

Results Transparency

50%

2 of 4 completed with results

Key Signals

2 with results80% success

Data Visualizations

Phase Distribution

18Total
Not Applicable (2)
P 1 (9)
P 2 (4)
P 3 (2)
P 4 (1)

Trial Status

Recruiting6
Not Yet Recruiting6
Completed4
Active Not Recruiting3
Suspended1
Terminated1

Trial Success Rate

80.0%

Benchmark: 86.5%

Based on 4 completed trials

Clinical Trials (21)

Showing 20 of 20 trials
NCT07469891Phase 1Recruiting

A Phase 1 Study of PRT12396 in Participants With Select Myeloproliferative Neoplasms

NCT06887803Phase 1RecruitingPrimary

A Study of Roginolisib in Combination With Ruxolitinib in Patients With Myelofibrosis (MF) Who Are Unresponsive to JAK Inhibitors

NCT07539779Phase 2Not Yet Recruiting

Luspatercept in Preventing Poor Erythroid Engraftment for Hematological Malignancies With Moderate to Severe Myelofibrosis

NCT07302776Phase 1Not Yet Recruiting

TACrolimus Targeted Immunosuppression Cessation in ALlogeneic HCT

NCT07529951Phase 1Not Yet Recruiting

Study of ZE74-0282 for Patients With JAK2 V617F Positive Blood Cancers

NCT07498205Phase 4Not Yet Recruiting

Comparing Momelotinib and Ruxolitinib in People With Untreated Myelofibrosis and Low Blood Cell Counts

NCT04472598Phase 3CompletedPrimary

Study of Oral Navitoclax Tablet In Combination With Oral Ruxolitinib Tablet When Compared With Oral Ruxolitinib Tablet To Assess Change In Spleen Volume In Adult Participants With Myelofibrosis

NCT07471503Phase 2Not Yet RecruitingPrimary

Gecacitinib Pre-, During- and Post-HSCT for Patients With Primary or Secondary Myelofibrosis

NCT07419178Not ApplicableRecruitingPrimary

A New Diagnostic Algorithm to Non-invasively Track Fibrotic Changes in Myeloproliferative Neoplasms Based on C-C Chemokine Receptor 2 Detection. From Flow Cytometry to the Development of Targeted Positron Emission Tomography Molecular Imaging. Pre-clinical Studies and First In-human Proof of Concept

NCT07362225Recruiting

MPN PROGRESSion Registry: Observational Study Tracking Symptoms, Treatments, and Disease Progression in People With Myeloproliferative Neoplasms (MPNs)

NCT03222609Phase 2CompletedPrimary

A Study Evaluating Tolerability and Efficacy of Navitoclax Alone or in Combination With Ruxolitinib in Participants With Myelofibrosis

NCT04468984Phase 3Active Not RecruitingPrimary

Study of Oral Navitoclax Tablet in Combination With Oral Ruxolitinib Tablet Versus Best Available Therapy to Assess Change in Spleen Volume in Adult Participants With Relapsed/Refractory Myelofibrosis

NCT07128381Phase 1RecruitingPrimary

Phase I/II Clinical Trial of Axatilimab, a CSF1R Monoclonal Antibody, in Combination With Ruxolitinib as Therapy for Patients With Myelofibrosis (MF) and Chronic Myelomonocytic Leukemia (CMML)

NCT06541249Phase 2Recruiting

MethoTRExATE in MyelOpRolifErative Neoplasms (TREATMORE) Trial

NCT07249606Not Yet RecruitingPrimary

Momelotinib Effectiveness in Myelofibrosis

NCT04454658Phase 1Active Not RecruitingPrimary

Safety and Tolerability Study of Oral ABBV-744 Tablet Alone or in Combination With Oral Ruxolitinib Tablet or Oral Navitoclax Tablet in Adult Participants With Myelofibrosis

NCT06798805Active Not Recruiting

Unraveling the Role of Extracellular Vesicles-driven Senescence in Myeloproliferative Neoplasms

NCT04480086Phase 1TerminatedPrimary

Safety and Tolerability Study of Mivebresib Tablet Alone or in Combination With Ruxolitinib Tablet or Navitoclax Tablet in Adult Participants With Myelofibrosis

NCT01816256Not ApplicableCompleted

Screening for Asymptomatic Portal Vein Thrombosis and Portal Hypertension in Patients With Philadelphia Negative Myeloproliferative Neoplasms

NCT01224496Phase 1Completed

Traditional Chinese Medicine in the Supportive Management of Anaemic and Cytopenic (Leukopenia, Thrombocytopenia) Haematological Disorders

Scroll to load more

Research Network

Activity Timeline