Key Insights

Highlights

Success Rate

77% trial completion

Published Results

62 trials with published results (27%)

Research Maturity

96 completed trials (41% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

12.4%

29 terminated out of 233 trials

Success Rate

76.8%

-9.7% vs benchmark

Late-Stage Pipeline

8%

18 trials in Phase 3/4

Results Transparency

65%

62 of 96 completed with results

Key Signals

62 with results77% success29 terminated

Data Visualizations

Phase Distribution

200Total
Not Applicable (15)
Early P 1 (5)
P 1 (88)
P 2 (74)
P 3 (16)
P 4 (2)

Trial Status

Completed96
Recruiting50
Terminated29
Active Not Recruiting24
Unknown15
Withdrawn11

Trial Success Rate

76.8%

Benchmark: 86.5%

Based on 96 completed trials

Clinical Trials (233)

Showing 20 of 20 trials
NCT01973881RecruitingPrimary

Quantitative MRI for Myelofibrosis

NCT07734077Phase 1Not Yet RecruitingPrimary

Revumenib in Patients With Myelofibrosis

NCT02506933Phase 2Active Not Recruiting

Multi-antigen CMV-MVA Triplex Vaccine in Reducing CMV Complications in Patients Previously Infected With CMV and Undergoing Donor Hematopoietic Cell Transplant

NCT06773195Phase 1RecruitingPrimary

A Study of Ruxolitinib in Combination With Ulixertinib in People With Myelofibrosis

NCT07020533Phase 1Recruiting

A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant

NCT07608666Phase 1Active Not RecruitingPrimary

Study to Evaluate the Effect of Rabeprazole Sodium Enteric-coated Tablets on the Pharmacokinetics of TQ05105 Tablets

NCT07623161Phase 3RecruitingPrimary

A Study to Compare Elritercept to Placebo in Adults With Myelofibrosis and Anemia Who Are Taking Ruxolitinib

NCT07250646Phase 1Recruiting

A Study of Rebecsinib for Patients With Relapsed/Refractory Secondary Acute Myeloid Leukemia or High Risk Myelofibrosis

NCT05320198Phase 1Recruiting

Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia

NCT04603495Phase 3Active Not RecruitingPrimary

Phase 3 Study of Pelabresib (CPI-0610) in Myelofibrosis (MF) (MANIFEST-2)

NCT03480360Phase 3Completed

Haploidentical Allogeneic Peripheral Blood Transplantation: Examining Checkpoint Immune Regulators' Expression

NCT05233618Phase 1Active Not RecruitingPrimary

Study of Tagraxofusp for Post-Transplant Maintenance for Patients With CD 123+ AML, MDS, MF and CMML (HSCT 002)

NCT07708272Phase 1Not Yet RecruitingPrimary

QT Interval/Corrected QT Interval (QT/QTc) Clinical Study to Evaluate the Cardiac Safety of TQ05105 Tablets in Healthy Participants

NCT04717414Phase 3Active Not Recruiting

An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Subjects With Myeloproliferative Neoplasm-Associated Myelofibrosis on Concomitant JAK2 Inhibitor Therapy and Who Require Red Blood Cell Transfusions

NCT02530034Phase 1Active Not Recruiting

Hu8F4 in Treating Patients With Advanced Hematologic Malignancies

NCT07551427Phase 2RecruitingPrimary

A Clinical Trial to Evaluate the Efficacy, Safety, and Pharmacokinetics of TQ05105 Tablets in Subjects With Intermediate/High-risk Myelofibrosis

NCT06533813RecruitingPrimary

Clinical Epidemiology in Contemporary Patients With Myelofibrosis.

NCT03427866Phase 2CompletedPrimary

Ruxolitinib Pre-, During- and Post-HSCT for Patients With Primary or Secondary Myelofibrosis.

NCT04576156Phase 3Active Not RecruitingPrimary

A Study Comparing Imetelstat Versus Best Available Therapy for the Treatment of Intermediate-2 or High-risk Myelofibrosis (MF) Who Have Not Responded to Janus Kinase (JAK)-Inhibitor Treatment

NCT07521046Phase 1Not Yet RecruitingPrimary

Tolerability of Ropeginterferon Alfa-2b Add-on to Ongoing Ruxolitinib Therapy in Myelofibrosis (RopeRux in Myelofibrosis)

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