Key Insights

Highlights

Success Rate

78% trial completion

Published Results

59 trials with published results (26%)

Research Maturity

95 completed trials (41% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

11.8%

27 terminated out of 229 trials

Success Rate

77.9%

-8.6% vs benchmark

Late-Stage Pipeline

7%

17 trials in Phase 3/4

Results Transparency

62%

59 of 95 completed with results

Key Signals

59 with results78% success27 terminated

Data Visualizations

Phase Distribution

196Total
Not Applicable (15)
Early P 1 (5)
P 1 (85)
P 2 (74)
P 3 (15)
P 4 (2)

Trial Status

Completed95
Recruiting48
Terminated27
Active Not Recruiting24
Unknown15
Withdrawn11

Trial Success Rate

77.9%

Benchmark: 86.5%

Based on 95 completed trials

Clinical Trials (229)

Showing 20 of 20 trials
NCT04888741Phase 2Recruiting

Methods of T Cell Depletion Trial (MoTD)

NCT04771572Phase 1Recruiting

Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

NCT07281781Phase 1RecruitingPrimary

Treating Anemia in Myelofibrosis With Repurposed Drugs (Nelfinavir) That Restore Iron Delivery to the Bone Marrow

NCT05320198Phase 1Recruiting

Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia

NCT04176198Phase 1RecruitingPrimary

A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis

NCT07551427Phase 2Not Yet RecruitingPrimary

A Clinical Trial to Evaluate the Efficacy, Safety, and Pharmacokinetics of TQ05105 Tablets in Subjects With Intermediate/High-risk Myelofibrosis

NCT03878199Phase 1Terminated

Testing the Effect of Taking Ruxolitinib and CPX-351 in Combination for the Treatment of Advanced Phase Myeloproliferative Neoplasms

NCT06781099Not ApplicableRecruiting

Feasibility Trial of Extracorporeal Iron Purification in Patients With Myelodysplastic Syndrome or Myelofibrosis

NCT07379125Phase 1Not Yet RecruitingPrimary

Therapeutic RSK1 Targeting in Myelofibrosis

NCT07521046Phase 1Not Yet RecruitingPrimary

Tolerability of Ropeginterferon Alfa-2b Add-on to Ongoing Ruxolitinib Therapy in Myelofibrosis (RopeRux in Myelofibrosis)

NCT03069326Phase 2Active Not RecruitingPrimary

A Clinical Study to Test the Effects of Ruxolitinib And Thalidomide Combination for Patients With Myelofibrosis

NCT03289910Phase 2Active Not Recruiting

Topotecan Hydrochloride and Carboplatin With or Without Veliparib in Treating Advanced Myeloproliferative Disorders and Acute Myeloid Leukemia or Chronic Myelomonocytic Leukemia

NCT04562389Phase 3Active Not RecruitingPrimary

Study of Selinexor in Combination With Ruxolitinib in Myelofibrosis

NCT07498205Phase 4Not Yet RecruitingPrimary

Comparing Momelotinib and Ruxolitinib in People With Untreated Myelofibrosis and Low Blood Cell Counts

NCT06351631Phase 3Recruiting

A Study to Evaluate Safety and Efficacy of Bomedemstat (MK-3543-017)

NCT04279847Phase 1Active Not RecruitingPrimary

Safety and Tolerability Study of INCB057643 in Participants With Myelofibrosis and Other Advanced Myeloid Neoplasms

NCT07104799Phase 1RecruitingPrimary

Momelotinib During and After HCT in Myelofibrosis

NCT04328844Phase 1Active Not Recruiting

A Study to Assess a PI3Kδ Inhibitor (IOA-244) in Patients With Metastatic Cancers

NCT06976918Recruiting

Registry Platform Myelofibrosis and Anemia

NCT06063486Phase 2Recruiting

Curcumin to Improve Inflammation and Symptoms in Patients With Clonal Cytopenia of Undetermined Significance, Low Risk Myelodysplastic Syndrome, and Myeloproliferative Neoplasms

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